Project description DEENESFRITPL Identifying digital endpoints for fatigue and sleep Patients with neurodegenerative disorders (NDD) and immune-mediated inflammatory diseases (IMID) are often affected by fatigue and sleep disturbances. These two disabling symptoms lead to poor quality of life and high healthcare costs. However, existing approaches to evaluate them are based on questionnaire methodology and have significant limitations. As a consequence, they are not reliable and do not take the impact of therapies into consideration. The EU-funded IDEA-FAST project will identify new digital endpoints for fatigue and sleep disturbances and offer a more objective and reliable evaluation of the seriousness and the effects of the symptoms. The purpose of the project is to understand the key mechanisms of these two disturbances and improve clinical trials envisaging new therapies with lower costs. Show the project objective Hide the project objective Objective Fatigue and sleep disturbances are two common and disabling symptoms that affect patients with neurodegenerative disorders (NDD) and immune-mediated inflammatory diseases (IMID). These symptoms are major predictors of poor quality of life and increased healthcare cost. Current questionnaire-based approaches to measure these symptoms have key limitations preventing them from being used as reliable endpoints in clinical trials to evaluate the effect of therapies. IDEA-FAST aims to address these issues by identifying novel digital endpoints for fatigue and sleep disturbances that will provide more objective, sensitive and reliable measures of the severity and impact of these symptoms in ecological settings. Such digital endpoints will not only help to gain insight into the underpinning mechanisms of fatigue and sleep disturbances, but will also vastly improve the efficiency of clinical trials, ultimately reducing the time and cost to bring new therapies to patients.To identify these digital endpoints, we will follow the recommendations of the Clinical Trials Transformation Initiative (CTTI). We will identify the characteristics that fatigue and sleep disturbances will have impact, then select the digital measures (endpoints) to quantify them, followed by choosing the appropriate digital device/technology accordingly. We will then perform a pilot study to prioritise a few of these candidate digital endpoints for validation. We will test the performance of these digital endpoints in two NDD and four IMID in a large longitudinal study during which extensive relevant clinical data will be collected. If these digital endpoints were validated, we will seek support from EMA/FDA for their qualification. Patient users’ perspective, ethical, data privacy, legal and other regulatory issues will be taken into consideration in all aspects of our proposal. The resultant digital biobank from the longitudinal study will become an invaluable resource for future exploitation. Fields of science medical and health sciencesclinical medicinepsychiatrysleep disordersmedical and health scienceshealth sciencesinflammatory diseases Keywords Immune-mediated inflammatory disorders Digital endpoints Fatigue Sleep disturbances Activity Daily Living Health-related Quality of Life Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.7. - Innovative Medicines Initiative 2 (IMI2) Topic(s) IMI2-2018-15-06 - Digital endpoints in neurodegenerative and immune-mediated diseases Call for proposal H2020-JTI-IMI2-2018-15-two-stage See other projects for this call Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSITY OF NEWCASTLE UPON TYNE Net EU contribution € 4 960 260,05 Address Kings gate NE1 7RU Newcastle upon tyne United Kingdom See on map Region North East (England) Northumberland and Tyne and Wear Tyneside Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 27 575,00 Participants (57) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN Germany Net EU contribution € 2 990 639,20 Address Ratzeburger allee 160 23562 Lübeck See on map Region Schleswig-Holstein Schleswig-Holstein Lübeck, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Germany Net EU contribution € 0,00 Address Olshausenstrasse 40 24118 Kiel See on map Region Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. UNIVERSITAET zu LUEBECK Germany Net EU contribution € 240 000,00 Address Ratzeburger allee 160 23562 Lubeck See on map Region Schleswig-Holstein Schleswig-Holstein Lübeck, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA DEGLI STUDI DI BRESCIA Italy Net EU contribution € 524 000,00 Address Piazza mercato 15 25121 Brescia See on map Region Nord-Ovest Lombardia Brescia Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Netherlands Net EU contribution € 439 500,00 Address Dr molewaterplein 40 3015 GD Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF GLASGOW United Kingdom Net EU contribution € 251 921,25 Address University avenue G12 8QQ Glasgow See on map Region Scotland West Central Scotland Glasgow City Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. GREATER GLASGOW HEALTH BOARD United Kingdom Net EU contribution € 62 078,75 Address Great western road 1055 j b russell G12 0XH Glasgow See on map Region Scotland West Central Scotland Glasgow City Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF LIMERICK Ireland Net EU contribution € 112 225,00 Address National technological park, plassey - Limerick See on map Region Ireland Northern and Western Border Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK France Net EU contribution € 362 774,50 Address 30 bd saint-jacques batiment b 75014 Paris See on map Region Ile-de-France Ile-de-France Paris Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO CLINICO SAN CARLOS Spain Net EU contribution € 49 032,50 Address Calle profesor martin lagos 28040 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Ireland Net EU contribution € 205 375,00 Address Western road T12 YN60 Cork See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. KKS-NETZWERK EV -NETZWERK DER KOORDINIERUNGSZENTREN FUR KLINISCHE STUDIEN Germany Net EU contribution € 90 000,00 Address Alt-moabit 96 a 10559 Berlin See on map Region Berlin Berlin Berlin Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 QUEEN MARY UNIVERSITY OF LONDON United Kingdom Net EU contribution € 304 000,00 Address 327 mile end road E1 4NS London See on map Region London Inner London — East Tower Hamlets Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom Net EU contribution € 2 345 530,00 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BYTEFLIES Belgium Net EU contribution € 199 915,00 Address Borsbeeksebrug 22-6th fl. 2600 Antwerpen See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Vlaams Gewest Prov. Antwerpen Arr. Antwerpen Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 DREEM France Net EU contribution € 195 250,00 Address 34 boulevard des italiens 75009 Paris See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Paris Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom Net EU contribution € 595 165,00 Address Trinity lane the old schools CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LIXOFT SAS Participation ended France Net EU contribution € 242 776,45 Address 8 rue de la renaissance batiment d 92160 Antony See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Hauts-de-Seine Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ASOCIACION PARKINSON MADRID Spain Net EU contribution € 250 000,00 Address Andres torrejon 18 28014 Madrid See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STICHTING MLC FOUNDATION Participation ended Netherlands Net EU contribution € 200 000,00 Address Jaarbeursplein 6 3521 AL Utrecht See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Utrecht Utrecht Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TMF - TECHNOLOGIE UND METHODENPLATTFORM FUR DIE VERNETZTE MEDIZINISCHE FORSCHUNG EV Germany Net EU contribution € 460 000,00 Address Charlottenstrasse 42 ecke dorotheenstrasse 10117 Berlin See on map Region Berlin Berlin Berlin Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MEDIBIOSENSE LTD United Kingdom Net EU contribution € 654 702,50 Address 34 weir road westwoodside DN9 2PG Doncaster See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Yorkshire and the Humber East Yorkshire and Northern Lincolnshire North and North East Lincolnshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EMPIRICA GESELLSCHAFT FUR KOMMUNIKATIONS UND TECHNOLOGIEFORSCHUNG MBH Germany Net EU contribution € 473 750,00 Address Oxfordstrasse 2 53111 Bonn See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS Portugal Net EU contribution € 285 000,00 Address Campo grande, edificio c1, piso 3 1749 016 Lisbon See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA Portugal Net EU contribution € 65 000,00 Address Campo grande c5 piso 3 1749-016 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 PLURIBUS ONE SRL Italy Net EU contribution € 287 500,00 Address Via vincenzo bellini 9 09128 Cagliari See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Isole Sardegna Cagliari Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES Portugal Net EU contribution € 289 500,00 Address Avenida prof egas moniz 1649 028 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEKNOLOGIAN TUTKIMUSKESKUS VTT OY Finland Net EU contribution € 685 141,25 Address Tekniikantie 21 02150 Espoo See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CAMBRIDGE COGNITION LIMITED United Kingdom Net EU contribution € 150 000,00 Address Tunbridge court tunbridge lane, bottisham cambs CB25 9TU Cambridge See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region East of England East Anglia Cambridgeshire CC Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDAD AUTONOMA DE MADRID Spain Net EU contribution € 120 000,00 Address Calle einstein 3 ciudad univ cantoblanco rectorado 28049 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT MINES-TELECOM France Net EU contribution € 356 750,00 Address 19 place marguerite perey 91120 Palaiseau See on map Region Ile-de-France Ile-de-France Essonne Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MCROBERTS BV Netherlands Net EU contribution € 159 125,00 Address Raamweg 43 2596HN 's-gravenhage (den haag) See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 GEORGE-HUNTINGTON-INSTITUT GMBH Germany Net EU contribution € 328 075,00 Address Johann krane weg 27 48149 Munster See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTYTUT PSYCHIATRII I NEUROLOGII Poland Net EU contribution € 170 000,00 Address Ulica sobieskiego 9 02 957 Warszawa See on map Region Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MEDIZINISCHE UNIVERSITAT INNSBRUCK Austria Net EU contribution € 353 125,00 Address Christoph probst platz 1 6020 Innsbruck See on map Region Westösterreich Tirol Innsbruck Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HELSE STAVANGER HF Norway Net EU contribution € 244 500,00 Address Gerd ragna bloch thorsens gate 8 4011 Stavanger See on map Region Norge Vestlandet Rogaland Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 IXSCIENT LIMITED United Kingdom Net EU contribution € 400 750,00 Address Popes grove 76 TW1 4JX Twickenham middlesex See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region London Outer London — West and North West Hounslow and Richmond upon Thames Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROPEAN FEDERATION OF CROHN'S AND ULCERATIVE COLITIS ASSOCIATIONS Belgium Net EU contribution € 35 000,00 Address Rue des chartreux 33 1000 Bruxelles / brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ACADEMISCH ZIEKENHUIS LEIDEN Netherlands Net EU contribution € 134 500,00 Address Albinusdreef 2 2333 ZA Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE UNIVERSITY OF MANCHESTER United Kingdom Net EU contribution € 167 500,00 Address Oxford road M13 9PL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. MANCHESTER UNIVERSITY NHS FOUNDATION TRUST Participation ended United Kingdom Net EU contribution € 0,00 Address Oxford road M13 9WL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 JANSSEN PHARMACEUTICA NV Belgium Net EU contribution € 0,00 Address Turnhoutseweg 30 2340 Beerse See on map Region Vlaams Gewest Prov. Antwerpen Arr. Turnhout Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 6 500 600,00 International partner Legal entity established in a non-associated third country that is not eligible for funding under Article 10 of the Regulation (EU) No 1290/2013 laying down the rules for participation and dissemination in Horizon 2020. CHDI Foundation, Inc. Not active in the Specific Grant Agreement of the project United States Address 350 7th avenue, suite 200 10001 New york See on map Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window TAKEDA DEVELOPMENT CENTRE EUROPE LTD Participation ended United Kingdom Net EU contribution € 0,00 Address Aldwych 61 WC2B 4AE London See on map Region London Inner London — West Westminster Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 242 855,24 ABBVIE INC United States Net EU contribution € 0,00 Address North waukegan road 1 60064 North chicago il See on map Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 995 906,00 ASTRAZENECA AB Sweden Net EU contribution € 0,00 Address Vastra maelarhamnen 151 85 Sodertaelje See on map Region Östra Sverige Stockholm Stockholms län Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 300 800,00 ELI LILLY AND COMPANY LTD United Kingdom Net EU contribution € 0,00 Address Lilly house basingview RG21 4FA Basingstoke See on map Region South East (England) Hampshire and Isle of Wight North Hampshire Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 300 000,00 PARKINSON'S DISEASE SOCIETY OF THEUNITED KINGDOM LBG United Kingdom Net EU contribution € 0,00 Address Vauxhall bridge raod 215 SW1V 1EJ London See on map Region London Inner London — West Westminster Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 197 250,00 PFIZER LIMITED United Kingdom Net EU contribution € 0,00 Address Ramsgate road CT13 9NJ Sandwich See on map Region South East (England) Kent East Kent Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 500 000,00 F. HOFFMANN-LA ROCHE AG Switzerland Net EU contribution € 0,00 Address Grenzacherstrasse 124 4070 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 1 000 000,00 SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT France Net EU contribution € 0,00 Address Pierre brossolette 1 91380 Chilly mazarin See on map Region Ile-de-France Ile-de-France Essonne Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 3 995 000,00 UCB BIOPHARMA Belgium Net EU contribution € 0,00 Address Allee de la recherche 60 1070 Bruxelles / brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 500 000,00 BIOGEN IDEC LIMITED United Kingdom Net EU contribution € 0,00 Address Innovation house 70 norden road SL6 3AY Maidenhead See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Berkshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 2 000 000,00 ORION OYJ Finland Net EU contribution € 0,00 Address Orionintie 1 02200 Espoo See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 170 000,00 TAKEDA PHARMACEUTICALS INTERNATIONAL AG Switzerland Net EU contribution € 0,00 Address Thurgauerstrasse 130 8152 Glattpark See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 2 757 124,76 LET IT CARE France Net EU contribution € 257 161,05 Address 11 av de la marquise du deffand 92160 Antony See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Hauts-de-Seine Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STICHTING LYGATURE Netherlands Net EU contribution € 300 000,00 Address Jaarbeursplein 6 3521 AL Utrecht See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Utrecht Utrecht Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
