Ubiquitin Chains in Viral Infections

Project Information

CHUbVi

Grant agreement ID: 856581

DOI 10.3030/856581

EC signature date 9 December 2019

Start date 1 March 2020

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 7 649 848,00

EU contribution € 7 649 848,00

Coordinated by

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
Switzerland

Publications

Peer reviewed articles (10)

Site-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9

Author(s): Akimoto, G.; Fernandes, A. P.; Bode, J. W
Published in: ACS central science, 2022, Page(s) 275–281, ISSN 2374-7951
Publisher: ACS Publications
DOI: 10.1021/acscentsci.1c01490

Chemoproteomik-basierende Zielprotein-Dekonvolution und Erstellung der Selektivitätsprofile von Histone Deacetylase Inhibitoren

Author(s): Lechner, Severin
Published in: Nature Communications, Issue 3, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39151-8

Atomic Tailoring of Ubiquitin Side Chains Influences E2-Mediated Ubiquitin Chain Formation

Author(s): Haewon Song; Toshiki Mikami; Sohei Majima; Jeffrey Bode
Published in: Crossref, Issue 5, 2024, ISSN 0018-019X
Publisher: Verlag Helvetica Chimica Acta
DOI: 10.26434/chemrxiv-2023-26rl0

Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives

Author(s): Etibor TA, Yamauchi Y, Amorim MJ
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030366

How Influenza Virus Uses Host Cell Pathways during Uncoating

Author(s): Etori Aguiar Moreira, Yohei Yamauchi, Patrick Matthias
Published in: Cells, Issue 10/7, 2021, Page(s) 1722, ISSN 2073-4409
Publisher: Cells
DOI: 10.3390/cells10071722

The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses

Author(s): Maria Giulia Bigotti; Katja Klein; Esther S. Gan; Maria Anastasina; Simon Andersson; Olli Vapalahti; Pekka Katajisto; Maximilian Erdmann; Andrew D. Davidson; Sarah J. Butcher; Ian Collinson; Eng Eong Ooi; Giuseppe Balistreri; Andrea Brancaccio; Yohei Yamauchi
Published in: Bigotti , M G , Klein , K , Gan , E S , Anastasina , M , Andersson , S , Vapalahti , O , Katajisto , P , Erdmann , M , Davidson , A D , Butcher , S J , Collinson , I , Ooi , E E , Balistreri , G , Brancaccio , A & Yamauchi , Y 2024 , ' The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses ' , Antiviral Research , vol. 224 , 105837 . https://doi, Issue 2, 2024, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1101/2023.11.06.565781

Neuropilin-1 is a host factor for SARS-CoV-2 infection.

Author(s): James L. Daly; Boris Simonetti; Katja Klein; Kai-En Chen; Maia Kavanagh Williamson; Carlos Antón-Plágaro; Deborah K. Shoemark; Lorena Simón-Gracia; Michael Bauer; Reka Hollandi; Urs F. Greber; Peter Horvath; Peter Horvath; Richard B. Sessions; Ari Helenius; Julian A. Hiscox; Julian A. Hiscox; Tambet Teesalu; David A. Matthews; Andrew D. Davidson; Brett M. Collins; Peter J. Cullen; Yohei Yamauch
Published in: Science, Issue 2, 2020, Page(s) 861-865, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abd3072

A widespread viral entry mechanism: The C-end Rule motif–neuropilin receptor interaction

Author(s): Balistreri G, Yamauchi Y, Teesalu T. A widespread viral entry mechanism: The C-end Rule motif-neuropilin receptor interaction.
Published in: Proceedings of the National Academy of Sciences (PNAS), 2021, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2112457118

ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1

Author(s): Simonetti B, Daly JL, Simón-Gracia L, Klein K, Weeratunga S, Antón-Plágaro C, Tobi A, Hodgson L, Lewis P, Heesom KJ, Shoemark DK, Davidson AD, Collins BM, Teesalu T, Yamauchi Y, Cullen PJ
Published in: Proceedings of the National Academy of Sciences (PNAS), 2022, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1101/2022.01.20.477115

Biocompatible lysine protecting groups for the chemoenzymatic synthesis of K48/K63 heterotypic and branched ubiquitin chains

Author(s): Toshiki Mikami; Sohei Majima; Haewon Song; Jeffrey W. Bode
Published in: ACS Central Science, Vol 9, Iss 8, Pp 1633-1641 (2023), Issue 3, 2023, ISSN 2374-7943
Publisher: ACS Publication
DOI: 10.26434/chemrxiv-2023-hlk3f

Other (1)

Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways

Author(s): Wang L, Moreira EA, Kempf G, Miyake Y, Oliveira Esteves BI, Fahmi A, Schaefer JV, Dreier B, Yamauchi Y, Alves MP, Plückthun A and Matthias P
Published in: 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.110736