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Active Monitoring of Cancer As An Alternative To Surgery

Deliverables

Publications

In Vivo Imaging Evaluation of Fluorescence Intensity at Tail Emission of Near-Infrared-I (NIR-I) Fluorophores in a Porcine Model

Author(s): Rodríguez-Luna MR, Okamoto N, Al-Taher M, Keller DS, Cinelli L, Hoskere Ashoka A, Klymchenko AS, Marescaux J, Diana M.
Published in: Life, 2022, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life12081123

Submucosal Regrowths after Watch and Wait in Rectal Cancer: A Case Series

Author(s): Ilaria Prata; Sofieke J. D. Temmink; Shirin Shahbazi Feshtali; Alexander L. Vahrmeijer; Stijn Crobach; Elke E. M. Peters; Jurjen J. Boonstra; Fabian A. Holman; Koen C. M. J. Peeters
Published in: Annals of Case Reports, Issue 4, 2023, ISSN 2474-1655
Publisher: Annals of Clinical Case Reports
DOI: 10.29011/2574-7754.101180

Design of Nanoparticles in Cancer Therapy Based on Tumor Microenvironment Properties

Author(s): Mahdavi Firouzabadi, Bita; Maria Joseph, Joice; Censi, Roberta; Di Martino, Piera
Published in: Pharmaceutics, Issue 9, 2022, ISSN 2078-2489
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122708

Nanotechnology as a Versatile Tool for 19F-MRI Agent's Formulation: A Glimpse into the Use of Perfluorinated and Fluorinated Compounds in Nanoparticles

Author(s): Joice Maria Joseph; Maria Rosa Gigliobianco; Bita Mahdavi Firouzabadi; Roberta Censi; Piera Di Martino
Published in: Pharmaceutics, Issue 14, 2022, ISSN 1424-8247
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020382

Simultaneous, Multi-Channel, Near-Infrared Fluorescence Visualization of Mesenteric Lymph Nodes Using Indocyanine Green and Methylene Blue: A Demonstration in a Porcine Model.

Author(s): Okamoto N, Al-Difaie Z, Scheepers MHMC, Heuvelings DJI, Rodríguez-Luna MR, Marescaux J, Diana M, Stassen LPS, Bouvy ND, Al-Taher M.
Published in: Diagnostics (Basel), 2023, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics13081469

Computer-Assisted Differentiation between Colon-Mesocolon and Retroperitoneum Using Hyperspectral Imaging (HSI) Technology

Author(s): Okamoto N, Rodríguez-Luna MR, Bencteux V, Al-Taher M, Cinelli L, Felli E, Urade T, Nkusi R, Mutter D, Marescaux J, Hostettler A, Collins T, Diana M.
Published in: Diagnostics (Basel), 2022, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics12092225

Hyperspectral Imaging in Major Hepatectomies: Preliminary Results from the Ex-Machyna Trial

Author(s): Felli E, Cinelli L, Bannone E, Giannone F, Muttillo EM, Barberio M, Keller DS, Rodríguez-Luna MR, Okamoto N, Collins T, Hostettler A, Schuster C, Mutter D, Pessaux P, Marescaux J, Gioux S, Felli E, Diana M.
Published in: Cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14225591

An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study

Author(s): Cai L, Lambregts DMJ, Beets GL, Mass M, Pooch EHP, Guérendel C, Beets-Tan RGH, Benson S.
Published in: npj Precision Oncology, 2024, ISSN 2397-768X
Publisher: Springer Nature
DOI: 10.1038/s41698-024-00516-x

Nanoparticles targeting hematopoietic stem and progenitor cells: Multimodal carriers for the treatment of hematological diseases

Author(s): Cruz LJ, Rezaei S, Grosveld F, Philipsen S, Eich C.
Published in: Frontiers in Genome Editing, 2022, ISSN 2673-3439
Publisher: Frontiers media
DOI: 10.3389/fgeed.2022.1030285

Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD)

Author(s): Temmink SJD, Peeters KCMJ, Bahadoer RR, Kranenbarg EM, Roodvoets AGH, Melenhorst J, Burger JWA, Wolthuis A, Renehan AG, Figueiredo NL, Pares O, Martling A, Perez RO, Beets GL, van de Velde CJH, Nilsson PJ; International Watch & Wait Database (IWWD) Consortium.
Published in: British Journal of Surgery, 2023, ISSN 1365-2168
Publisher: Wiley
DOI: 10.1093/bjs/znad051

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Author(s): Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle
Published in: Cancer Gene Therapy, 2020, ISSN 0929-1903
Publisher: Nature Publishing Group
DOI: 10.1038/s41417-020-00224-1

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

Author(s): Vincent Q. Sier, Joost R. van der Vorst, Paul H. A. Quax, Margreet R. de Vries, Elham Zonoobi, Alexander L. Vahrmeijer, Ilona A. Dekkers, Lioe-Fee de Geus-Oei, Anke M. Smits, Weibo Cai, Cornelis F. M. Sier, Marie José T. H. Goumans, Lukas J. A. C. Hawinkels
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4804, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094804

Modulating the Crosstalk between the Tumor and the Microenvironment Using SiRNA: A Flexible Strategy for Breast Cancer Treatment

Author(s): Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Rosario Vincenzo Chianese, Francesco Palma, Alan Chan, Gerolama Condorelli
Published in: Cancers, Issue 12/12, 2020, Page(s) 3744, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123744

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

Author(s): Elham zonoobi
Published in: Molecular Sciences, Issue 3, 2021, ISSN 1424-8247
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.5281/zenodo.6594333

Clinical prediction models assessing response to radiotherapy for rectal cancer: protocol for a systematic review

Author(s): Margarita Karageorgou; David M. Hughes; Arthur Sun Myint; D. Mark Pritchard; Laura J. Bonnett
Published in: Diagnostic and prognostic research, Issue 2, 2022, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/s41512-022-00132-y

Complete response rates in rectal cancer: Temporal changes over a decade in a population-based nationwide cohort

Author(s): Temmink SJD, Martling A, Angenete E, Nilsson PJ.
Published in: European journal of surgical oncology, 2023, ISSN 0748-7983
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ejso.2023.106991

CEA, EpCAM, αvβ6 and uPAR Expression in Rectal Cancer Patients with a Pathological Complete Response after Neoadjuvant Therapy

Author(s): Daan Linders , Marion Deken , Maxime van der Valk , Willemieke Tummers , Shadhvi Bhairosingh , Dennis Schaap , Gesina van Lijnschoten , Elham Zonoobi , Peter Kuppen , Cornelis van de Velde , Alexander Vahrmeijer , Arantza Farina Sarasqueta , Cornelis Sier , Denise Hilling
Published in: Diagnostics (Basel), 2021, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics11030516

miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment

Author(s): Giuseppina Roscigno, Assunta Cirella, Alessandra Affinito, Cristina Quintavalle, Iolanda Scognamiglio, Francesco Palma, Francesco Ingenito, Silvia Nuzzo, Francesca De Micco, Antonio Cuccuru, Renato Thomas, Gerolama Condorelli
Published in: International Journal of Molecular Sciences, Issue 21/7, 2020, Page(s) 2313, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072313

Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Author(s): Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Published in: Molecules, Issue 25/5, 2020, Page(s) 1181, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25051181

Trident: A dual oxygenation and fluorescence imaging platform for realtime and quantitative surgical guidance.

Author(s): Ségaud S, Baratelli L, Felli E, Bannone E, Cinelli L, Rodríguez-Luna MR, Okamoto N, Keller DS, de Mathelin M, Lecler S, Diana M and Gioux S
Published in: Front. Photonics, 2022, ISSN 2673-6853
Publisher: Frontiers Media
DOI: 10.3389/fphot.2022.1032776

Colorectal polyps: Targets for fluorescence-guided endoscopy to detect high-grade dysplasia and T1 colorectal cancer

Author(s): Dekkers N, Zonoobi E, Dang H, Warmerdam MI, Crobach S, Langers AMJ, van der Kraan J, Hilling DE, Peeters KCMJ, Holman FA, Vahrmeijer AL, Sier CFM, Hardwick JCH, Boonstra JJ.
Published in: United European Gastroenterol J, 2022, ISSN 2050-6414
Publisher: Wiley
DOI: 10.1002/ueg2.12375

Erythrocyte-cancer hybrid membrane-coated reduction-sensitive nanoparticles for enhancing chemotherapy efficacy in breast cancer

Author(s): Rezaei S, de Araújo Júnior RF, da Silva ILG, Schomann T, Eich C, Cruz LJ.
Published in: Biomaterials Advances, 2023, ISSN 2772-9508
Publisher: Elsevier
DOI: 10.1016/j.bioadv.2023.213456

Multifunctional Role of Lipids in Modulating the Tumorigenic Properties of 4T1 Breast Cancer Cells

Author(s): Yuanyuan He; Somayeh Rezaei; Raimundo Fernandes de Araújo Júnior; Luis J. Cruz; Christina Eich
Published in: International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4240, Issue 22, 2022, ISSN 1424-8247
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23084240

Quantification of bowel ischaemia using real-time multispectral Single Snapshot Imaging of Optical Properties (SSOP)

Author(s): María Rita Rodríguez-Luna; Nariaki Okamoto; Lorenzo Cinelli; Luca Baratelli; Silvère Ségaud; Adriana Rodríguez-Gómez; Deborah S. Keller; Elham Zonoobi; Elisa Bannone; Jacques Marescaux; Michele Diana; Sylvain Gioux
Published in: Crossref, Issue 11, 2022, ISSN 0930-2794
Publisher: Springer Verlag
DOI: 10.1007/s00464-022-09764-z

Single Snapshot Imaging of Optical Properties (SSOP) for Perfusion Assessment during Gastric Conduit Creation for Esophagectomy: An Experimental Study on Pigs

Author(s): inelli L, Felli E, Baratelli L, Ségaud S, Baiocchini A, Okamoto N, Rodríguez-Luna MR, Elmore U, Rosati R, Partelli S, Marescaux J, Gioux S, Diana M
Published in: Cancers, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13236079

Watch and wait after a clinical complete response in rectal cancer patients younger than 50 years

Author(s): Renu R. Bahadoer, Koen C. M. J. Peeters, Geerard L. Beets, Nuno L. Figueiredo, Esther Bastiaannet, Alexander Vahrmeijer, Sofieke J. D. Temmink, W. M. Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Angelita Habr-Gama, Rodrigo O. Perez, Cornelis J. H van de Velde, Denise E. Hilling
Published in: British Journal of Surgery, Issue 00071323, 2021, ISSN 0007-1323
Publisher: John Wiley & Sons Inc.
DOI: 10.5281/zenodo.6550575

Critical appraisal of the economic evidence for a watch-and-wait strategy in people with clinical complete response following neoadjuvant chemoradiotherapy for rectal cancer: a systematic review

Author(s): Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Published in: Issue 10, 2022
Publisher: NIHR
DOI: 10.5281/zenodo.7550214

Protein interaction with biocompatible and biodegradable novel nanohydrogels

Author(s): Gigliobianco, Maria rosa; Mahdavi Firouzabadi, Bita; Censi, Roberta; Di Martino, Piera
Published in: Issue 7, 2022
Publisher: Biopharmaceutics And Pharmaceutical Technology
DOI: 10.5281/zenodo.6641669

Economic evidence for a watch-and-wait strategy in patients with clinical complete response following neoadjuvant chemoradiotherapy for rectal cancer: a systematic review and critical appraisal

Author(s): Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Published in: Issue 3, 2022
Publisher: The university of Manchester
DOI: 10.5281/zenodo.7510197

An improved automatic system for aiding the detection of colon polyps using deep learning

Author(s): Lishan Cai; Regina Beets-Tan; Sean Benson
Published in: 2021, ISBN 978-1-6654-0358-0
Publisher: IEEE
DOI: 10.1109/bhi50953.2021.9508557

Value Based Assessment Frameworks for Oncology: implications for valuing the outcomes for watch-and-wait after clinical complete response in rectal cancer (ValCoRe)

Author(s): Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Published in: Issue 9, 2022
Publisher: The university of Manchester
DOI: 10.5281/zenodo.7510315

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