Active Monitoring of Cancer As An Alternative To Surgery

Información del proyecto

CAST

Identificador del acuerdo de subvención: 857894

DOI

10.3030/857894

Proyecto cerrado

Fecha de la firma de la CE 11 Septiembre 2019

Fecha de inicio 1 Noviembre 2019

Fecha de finalización 31 Octubre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 057 658,68

Aportación de la UE

€ 4 057 658,68

Coordinado por

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

website

Publicaciones

Peer reviewed articles (33)

In Vivo Imaging Evaluation of Fluorescence Intensity at Tail Emission of Near-Infrared-I (NIR-I) Fluorophores in a Porcine Model

Autores: Rodríguez-Luna MR, Okamoto N, Al-Taher M, Keller DS, Cinelli L, Hoskere Ashoka A, Klymchenko AS, Marescaux J, Diana M.
Publicado en: Life, 2022, ISSN 2075-1729
Editor: MDPI
DOI: 10.3390/life12081123

Submucosal Regrowths after Watch and Wait in Rectal Cancer: A Case Series

Autores: Ilaria Prata; Sofieke J. D. Temmink; Shirin Shahbazi Feshtali; Alexander L. Vahrmeijer; Stijn Crobach; Elke E. M. Peters; Jurjen J. Boonstra; Fabian A. Holman; Koen C. M. J. Peeters
Publicado en: Annals of Case Reports, Edición 4, 2023, ISSN 2474-1655
Editor: Annals of Clinical Case Reports
DOI: 10.29011/2574-7754.101180

Design of Nanoparticles in Cancer Therapy Based on Tumor Microenvironment Properties

Autores: Mahdavi Firouzabadi, Bita; Maria Joseph, Joice; Censi, Roberta; Di Martino, Piera
Publicado en: Pharmaceutics, Edición 9, 2022, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122708

Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer - Multi-centre study

Autores: Wah Than N, Mark Pritchard D, Hughes DM, Shing Yu K, Minnaar HS, Dhadda A, Mills J, Folkesson J, Radu C, Duckworth CA, Wong H, Ul Haq M, Sripadam R, Halling-Brown MD, Stewart AJ, Sun Myint A.
Publicado en: Clinical and Translational Radiation Oncology, 2024, ISSN 2405-6308
Editor: Elsevier
DOI: 10.1016/j.ctro.2024.100851

Nanotechnology as a Versatile Tool for 19F-MRI Agent's Formulation: A Glimpse into the Use of Perfluorinated and Fluorinated Compounds in Nanoparticles

Autores: Joice Maria Joseph; Maria Rosa Gigliobianco; Bita Mahdavi Firouzabadi; Roberta Censi; Piera Di Martino
Publicado en: Pharmaceutics, Edición 14, 2022, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020382

Contact X-ray brachytherapy (CXB) as a salvage treatment for rectal cancer patients who developed local tumor re-growth after watch-and-wait approach

Autores: Than NW, Pritchard DM, Duckworth CA, Hughes DM, Wong H, Sripadam R, Myint AS
Publicado en: Journal of Contemporary Brachytherapy, 2024, ISSN 1689-832X
Editor: Termedia
DOI: 10.5114/jcb.2024.139049

Simultaneous, Multi-Channel, Near-Infrared Fluorescence Visualization of Mesenteric Lymph Nodes Using Indocyanine Green and Methylene Blue: A Demonstration in a Porcine Model.

Autores: Okamoto N, Al-Difaie Z, Scheepers MHMC, Heuvelings DJI, Rodríguez-Luna MR, Marescaux J, Diana M, Stassen LPS, Bouvy ND, Al-Taher M.
Publicado en: Diagnostics (Basel), 2023, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/diagnostics13081469

Computer-Assisted Differentiation between Colon-Mesocolon and Retroperitoneum Using Hyperspectral Imaging (HSI) Technology

Autores: Okamoto N, Rodríguez-Luna MR, Bencteux V, Al-Taher M, Cinelli L, Felli E, Urade T, Nkusi R, Mutter D, Marescaux J, Hostettler A, Collins T, Diana M.
Publicado en: Diagnostics (Basel), 2022, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/diagnostics12092225

MALDI imaging combined with two-photon microscopy reveals local differences in the heterogeneity of colorectal cancer

Autores: Arora B, Ajinkya K, Markus MA, Ramos-Gomes F, Bohnenberger H, Ströbel P, Alves F & Klein O.
Publicado en: NPJ Imagiing, 2024, ISSN 2948-197X
Editor: Nature Portfolio (subsidiary of Springer Nature)
DOI: 10.1038/s44303-024-00041-3

Results of a diagnostic imaging audit in a randomised clinical trial in rectal cancer highlight the importance of careful planning and quality control

Autores: Prata I, Eriksson M, Krdzalic J, Kranenbarg EM, Roodvoets AGH, Beets-Tan R, van de Velde CJH, van Etten B, Hospers GAP, Glimelius B, Nilsson PJ, Marijnen CAM, Peeters KCMJ, Blomqvist LK
Publicado en: Insights into Imaging, 2024, ISSN 1869-4101
Editor: Springer Science and Business Media Deutschland GmbH
DOI: 10.1186/s13244-023-01552-0

Hyperspectral Imaging in Major Hepatectomies: Preliminary Results from the Ex-Machyna Trial

Autores: Felli E, Cinelli L, Bannone E, Giannone F, Muttillo EM, Barberio M, Keller DS, Rodríguez-Luna MR, Okamoto N, Collins T, Hostettler A, Schuster C, Mutter D, Pessaux P, Marescaux J, Gioux S, Felli E, Diana M.
Publicado en: Cancers, 2022, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14225591

An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study

Autores: Cai L, Lambregts DMJ, Beets GL, Mass M, Pooch EHP, Guérendel C, Beets-Tan RGH, Benson S.
Publicado en: npj Precision Oncology, 2024, ISSN 2397-768X
Editor: Springer Nature
DOI: 10.1038/s41698-024-00516-x

Nanoparticles targeting hematopoietic stem and progenitor cells: Multimodal carriers for the treatment of hematological diseases

Autores: Cruz LJ, Rezaei S, Grosveld F, Philipsen S, Eich C.
Publicado en: Frontiers in Genome Editing, 2022, ISSN 2673-3439
Editor: Frontiers media
DOI: 10.3389/fgeed.2022.1030285

Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues

Autores: Arora B, Kulkarni A, Markus MA, Ströbel P, Bohnenberger H, Alves F, Ramos-Gomes F.
Publicado en: Scientific Reports, 2024, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-024-58231-3

Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD)

Autores: Temmink SJD, Peeters KCMJ, Bahadoer RR, Kranenbarg EM, Roodvoets AGH, Melenhorst J, Burger JWA, Wolthuis A, Renehan AG, Figueiredo NL, Pares O, Martling A, Perez RO, Beets GL, van de Velde CJH, Nilsson PJ; International Watch & Wait Database (IWWD) Consortium.
Publicado en: British Journal of Surgery, 2023, ISSN 1365-2168
Editor: Wiley
DOI: 10.1093/bjs/znad051

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Autores: Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle
Publicado en: Cancer Gene Therapy, 2020, ISSN 0929-1903
Editor: Nature Publishing Group
DOI: 10.1038/s41417-020-00224-1

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

Autores: Vincent Q. Sier, Joost R. van der Vorst, Paul H. A. Quax, Margreet R. de Vries, Elham Zonoobi, Alexander L. Vahrmeijer, Ilona A. Dekkers, Lioe-Fee de Geus-Oei, Anke M. Smits, Weibo Cai, Cornelis F. M. Sier, Marie José T. H. Goumans, Lukas J. A. C. Hawinkels
Publicado en: International Journal of Molecular Sciences, Edición 22/9, 2021, Página(s) 4804, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094804

Modulating the Crosstalk between the Tumor and the Microenvironment Using SiRNA: A Flexible Strategy for Breast Cancer Treatment

Autores: Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Rosario Vincenzo Chianese, Francesco Palma, Alan Chan, Gerolama Condorelli
Publicado en: Cancers, Edición 12/12, 2020, Página(s) 3744, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123744

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review

Autores: Elham zonoobi
Publicado en: Molecular Sciences, Edición 3, 2021, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.5281/zenodo.6594333

Clinical prediction models assessing response to radiotherapy for rectal cancer: protocol for a systematic review

Autores: Margarita Karageorgou; David M. Hughes; Arthur Sun Myint; D. Mark Pritchard; Laura J. Bonnett
Publicado en: Diagnostic and prognostic research, Edición 2, 2022, ISSN 1471-2458
Editor: BioMed Central
DOI: 10.1186/s41512-022-00132-y

Complete response rates in rectal cancer: Temporal changes over a decade in a population-based nationwide cohort

Autores: Temmink SJD, Martling A, Angenete E, Nilsson PJ.
Publicado en: European journal of surgical oncology, 2023, ISSN 0748-7983
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ejso.2023.106991

Contact X-ray Brachytherapy (CXB) as a boost therapy after neoadjuvant (chemo)radiation in high-risk locally advanced rectal cancer

Autores: Ngu Wah Than, D. Mark Pritchard, David M. Hughes, Carrie. A. Duckworth, Helen Wong, Muneeb Ul Haq, Rajaram Sripadam, Arthur Sun Myint
Publicado en: International Journal of Radiation Oncology*Biology*Physics, 2024, ISSN 0360-3016
Editor: Elsevier BV
DOI: 10.1016/j.ijrobp.2024.11.113

CEA, EpCAM, αvβ6 and uPAR Expression in Rectal Cancer Patients with a Pathological Complete Response after Neoadjuvant Therapy

Autores: Daan Linders , Marion Deken , Maxime van der Valk , Willemieke Tummers , Shadhvi Bhairosingh , Dennis Schaap , Gesina van Lijnschoten , Elham Zonoobi , Peter Kuppen , Cornelis van de Velde , Alexander Vahrmeijer , Arantza Farina Sarasqueta , Cornelis Sier , Denise Hilling
Publicado en: Diagnostics (Basel), 2021, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/diagnostics11030516

miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment

Autores: Giuseppina Roscigno, Assunta Cirella, Alessandra Affinito, Cristina Quintavalle, Iolanda Scognamiglio, Francesco Palma, Francesco Ingenito, Silvia Nuzzo, Francesca De Micco, Antonio Cuccuru, Renato Thomas, Gerolama Condorelli
Publicado en: International Journal of Molecular Sciences, Edición 21/7, 2020, Página(s) 2313, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072313

Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Autores: Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Publicado en: Molecules, Edición 25/5, 2020, Página(s) 1181, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25051181

Trident: A dual oxygenation and fluorescence imaging platform for realtime and quantitative surgical guidance.

Autores: Ségaud S, Baratelli L, Felli E, Bannone E, Cinelli L, Rodríguez-Luna MR, Okamoto N, Keller DS, de Mathelin M, Lecler S, Diana M and Gioux S
Publicado en: Front. Photonics, 2022, ISSN 2673-6853
Editor: Frontiers Media
DOI: 10.3389/fphot.2022.1032776

Colorectal polyps: Targets for fluorescence-guided endoscopy to detect high-grade dysplasia and T1 colorectal cancer

Autores: Dekkers N, Zonoobi E, Dang H, Warmerdam MI, Crobach S, Langers AMJ, van der Kraan J, Hilling DE, Peeters KCMJ, Holman FA, Vahrmeijer AL, Sier CFM, Hardwick JCH, Boonstra JJ.
Publicado en: United European Gastroenterol J, 2022, ISSN 2050-6414
Editor: Wiley
DOI: 10.1002/ueg2.12375

Erythrocyte-cancer hybrid membrane-coated reduction-sensitive nanoparticles for enhancing chemotherapy efficacy in breast cancer

Autores: Rezaei S, de Araújo Júnior RF, da Silva ILG, Schomann T, Eich C, Cruz LJ.
Publicado en: Biomaterials Advances, 2023, ISSN 2772-9508
Editor: Elsevier
DOI: 10.1016/j.bioadv.2023.213456

Multifunctional Role of Lipids in Modulating the Tumorigenic Properties of 4T1 Breast Cancer Cells

Autores: Yuanyuan He; Somayeh Rezaei; Raimundo Fernandes de Araújo Júnior; Luis J. Cruz; Christina Eich
Publicado en: International Journal of Molecular Sciences; Volume 23; Edición 8; Pages: 4240, Edición 22, 2022, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23084240

Quantification of bowel ischaemia using real-time multispectral Single Snapshot Imaging of Optical Properties (SSOP)

Autores: María Rita Rodríguez-Luna; Nariaki Okamoto; Lorenzo Cinelli; Luca Baratelli; Silvère Ségaud; Adriana Rodríguez-Gómez; Deborah S. Keller; Elham Zonoobi; Elisa Bannone; Jacques Marescaux; Michele Diana; Sylvain Gioux
Publicado en: Crossref, Edición 11, 2022, ISSN 0930-2794
Editor: Springer Verlag
DOI: 10.1007/s00464-022-09764-z

Single Snapshot Imaging of Optical Properties (SSOP) for Perfusion Assessment during Gastric Conduit Creation for Esophagectomy: An Experimental Study on Pigs

Autores: inelli L, Felli E, Baratelli L, Ségaud S, Baiocchini A, Okamoto N, Rodríguez-Luna MR, Elmore U, Rosati R, Partelli S, Marescaux J, Gioux S, Diana M
Publicado en: Cancers, 2021, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13236079

Watch and wait after a clinical complete response in rectal cancer patients younger than 50 years

Autores: Renu R. Bahadoer, Koen C. M. J. Peeters, Geerard L. Beets, Nuno L. Figueiredo, Esther Bastiaannet, Alexander Vahrmeijer, Sofieke J. D. Temmink, W. M. Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Angelita Habr-Gama, Rodrigo O. Perez, Cornelis J. H van de Velde, Denise E. Hilling
Publicado en: British Journal of Surgery, Edición 00071323, 2021, ISSN 0007-1323
Editor: John Wiley & Sons Inc.
DOI: 10.5281/zenodo.6550575

Sequence of Contact X-ray Brachytherapy (CXB) and External BeamRadiation (EBRT) in organ-preserving treatment for small rectal cancer

Autores: Than NW, Pritchard DM, Hughes DM, Duckworth CA, Wong H, Haq MU, Sripadam R, Myint AS.
Publicado en: Radiotherapy and Oncology, 2024, ISSN 0167-8140
Editor: Elsevier BV
DOI: 10.1016/j.radonc.2024.110465

Other (2)

Critical appraisal of the economic evidence for a watch-and-wait strategy in people with clinical complete response following neoadjuvant chemoradiotherapy for rectal cancer: a systematic review

Autores: Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Publicado en: Edición 10, 2022
Editor: NIHR
DOI: 10.5281/zenodo.7550214

Improving Rectal Tumor Segmentation with Anomaly Fusion Derived from Anatomical Inpainting: A Multicenter Study

Autores: Lishan Cai, Mohamed A. Abdelatty, Luyi Han, Doenja M. J. Lambregts, Joost van Griethuysen, Eduardo Pooch, Regina G.H. Beets-Tan, Sean Benson, Joren Brunekreef, Jonas Teuwen
Publicado en: medRxiv, 2024
Editor: CSHL
DOI: 10.1101/2024.10.15.24315517

Conference proceedings (4)

Protein interaction with biocompatible and biodegradable novel nanohydrogels

Autores: Gigliobianco, Maria rosa; Mahdavi Firouzabadi, Bita; Censi, Roberta; Di Martino, Piera
Publicado en: Edición 7, 2022
Editor: Biopharmaceutics And Pharmaceutical Technology
DOI: 10.5281/zenodo.6641669

Economic evidence for a watch-and-wait strategy in patients with clinical complete response following neoadjuvant chemoradiotherapy for rectal cancer: a systematic review and critical appraisal

Autores: Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Publicado en: Edición 3, 2022
Editor: The university of Manchester
DOI: 10.5281/zenodo.7510197

An improved automatic system for aiding the detection of colon polyps using deep learning

Autores: Lishan Cai; Regina Beets-Tan; Sean Benson
Publicado en: 2021, ISBN 978-1-6654-0358-0
Editor: IEEE
DOI: 10.1109/bhi50953.2021.9508557

Value Based Assessment Frameworks for Oncology: implications for valuing the outcomes for watch-and-wait after clinical complete response in rectal cancer (ValCoRe)

Autores: Thapa, Shabnam; Payne, Katherine; Thokala, Praveen; Malcomson, Lee; Renehan, Andrew G
Publicado en: Edición 9, 2022
Editor: The university of Manchester
DOI: 10.5281/zenodo.7510315