Project description
Innovative synthetic bone biomaterials
In bone transplantation procedures, grafts are obtained from the patients themselves, from bone banks or even animals. However, all these sources present with various disadvantages associated with immune compatibility, availability and disease transmission. The scope of the EU-funded Bone3Dmatch project is to revolutionise the industry of synthetic bone grafts by introducing novel biomaterials. These biomaterials have a high water consistency and mimic natural bone properties, supporting bone regeneration and patient recovery. Importantly, they can be 3D printed to produce scaffolds tailor-made to individual patient needs, which will allow the treatment of complex bone defects.
Objective
Over 2 million bone grafting procedures are performed annually worldwide nearly half of them in the EU, being the 2nd most transplanted tissue after blood. Bone defects pose a great clinical and socio-economic problem, only worsening with the ageing population. Even if bone harvested from the patient, bone banks or animals are common standard, they present serious disadvantages (limited availability, immune responses, disease transmission, ethical issues). Various synthetic bone grafts have been developed to minimize complications, yet with low success and failing to accelerate natural bone growth.
Bone3Dmatch revolutionizes the market of bone grafting (3.2bn€ globally) with a new generation of synthetic biomaterials. Two main disruptions are brought forward:
1) Biomimicry: The biomaterial, its aqueous composition and low-temperature processing is capable of mimicking the bone creation conditions. Thus, it is recognised as natural bone by bone cells, accelerating the bone regeneration and the patient’s recovery.
2) Patient customisation: Through advanced 3D printing technologies, it manufactures patient-specific scaffolds in less than 72h. This enables the treatment of complex bone defects, changing the current paradigm to a patient specific treatment.
The company behind Bone3Dmatch is MIMETIS, a young SME built on the back of 25 years of research and business acumen in biomaterials for bone regeneration. Currently, MIMETIS offers biomimetic granules for the dental market. With an investment of 1.1M€, Bone3Dmatch will accelerate the market introduction of the 4th generation biomaterial in a completely new form (3D-printed scaffolds). Targeting orthopaedics and cranio-maxillofacial, we expect to reach the market in 2020 achieving 4,9M€ in revenues in only 3 years. Moreover, our ambition is to deploy a decentralised model where hospitals around the world are able to print their own patient-specific implants using our biomimetic biomaterial.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine immunology
- medical and health sciences clinical medicine orthopaedics
- engineering and technology mechanical engineering manufacturing engineering additive manufacturing
- engineering and technology industrial biotechnology biomaterials
- medical and health sciences medical biotechnology implants artificial bone
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-2 - SME instrument phase 2
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
08290 Cerdanyola Del Valles Barcelona
Spain
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.