Project description
Innovative synthetic bone biomaterials
In bone transplantation procedures, grafts are obtained from the patients themselves, from bone banks or even animals. However, all these sources present with various disadvantages associated with immune compatibility, availability and disease transmission. The scope of the EU-funded Bone3Dmatch project is to revolutionise the industry of synthetic bone grafts by introducing novel biomaterials. These biomaterials have a high water consistency and mimic natural bone properties, supporting bone regeneration and patient recovery. Importantly, they can be 3D printed to produce scaffolds tailor-made to individual patient needs, which will allow the treatment of complex bone defects.
Objective
Over 2 million bone grafting procedures are performed annually worldwide nearly half of them in the EU, being the 2nd most transplanted tissue after blood. Bone defects pose a great clinical and socio-economic problem, only worsening with the ageing population. Even if bone harvested from the patient, bone banks or animals are common standard, they present serious disadvantages (limited availability, immune responses, disease transmission, ethical issues). Various synthetic bone grafts have been developed to minimize complications, yet with low success and failing to accelerate natural bone growth.
Bone3Dmatch revolutionizes the market of bone grafting (3.2bn€ globally) with a new generation of synthetic biomaterials. Two main disruptions are brought forward:
1) Biomimicry: The biomaterial, its aqueous composition and low-temperature processing is capable of mimicking the bone creation conditions. Thus, it is recognised as natural bone by bone cells, accelerating the bone regeneration and the patient’s recovery.
2) Patient customisation: Through advanced 3D printing technologies, it manufactures patient-specific scaffolds in less than 72h. This enables the treatment of complex bone defects, changing the current paradigm to a patient specific treatment.
The company behind Bone3Dmatch is MIMETIS, a young SME built on the back of 25 years of research and business acumen in biomaterials for bone regeneration. Currently, MIMETIS offers biomimetic granules for the dental market. With an investment of 1.1M€, Bone3Dmatch will accelerate the market introduction of the 4th generation biomaterial in a completely new form (3D-printed scaffolds). Targeting orthopaedics and cranio-maxillofacial, we expect to reach the market in 2020 achieving 4,9M€ in revenues in only 3 years. Moreover, our ambition is to deploy a decentralised model where hospitals around the world are able to print their own patient-specific implants using our biomimetic biomaterial.
Fields of science
- medical and health sciencesbasic medicineimmunology
- medical and health sciencesclinical medicineorthopaedics
- engineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturing
- engineering and technologyindustrial biotechnologybiomaterials
- medical and health sciencesmedical biotechnologyimplantsartificial bone
Programme(s)
Funding Scheme
SME-2 - SME instrument phase 2Coordinator
08290 Cerdanyola Del Valles Barcelona
Spain
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.