Gut-brain-axis: Targets for improvement of cognition in the elderly

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data management plan

A data management plan will be drawn up.

Project website and press release SmartAge opening

The project website will be opened and there will be a press release with respect to SmartAge opening

Kick-off Meeting, Consortium agreement

The Kick off meeting with all participants will take place and the CA will be signed

Publications

To Smooth or not to Smooth: Enhancing Specificity While Maintaining Sensitivity

Author(s): Eileen Luders, Robert Dahnke, Christian Gaser, null null
Published in: BioRxiv, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.06.11.495739

Approximation of bone mineral density and subcutaneous adiposity using T1-weighted images of the human head

Author(s): Polona Kalc, Felix Hoffstaedter, Eileen Luders, Christian Gaser, Robert Dahnke
Published in: BioXriv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.05.22.595163

APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites

Author(s): Almut Heinken, Timothy Otto Hulshof, Bram Nap, Filippo Martinelli, Arianna Basile, Amy O’Brolchain, Neil Francis O’Sullivan, Celine Gallagher, Eimer Magee, Francesca McDonagh, Ian Lalor, Maeve Bergin, Phoebe Evans, Rachel Daly, Ronan Farrell, Rose Marie Delaney, Saoirse Hill, Saoirse Roisin McAuliffe, Trevor Kilgannon, Ronan M.T. Fleming, Cyrille C. Thinnes, Ines Thiele
Published in: 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.10.02.560573

The MicroMap is a network visualisation resource for microbiome metabolism

Author(s): Cyrille C Thinnes, Renee Waschkowitz, Eoghan Courtney, Eoghan Culligan, Katie Fahy, Ruby A M Ferrazza, Ciara Ferris, Angeline Lagali, Rebecca Lane, Colm Maye, Olivia Murphy, David Noone, Saoirse Ryan, Mihaela Bet, Maria C Corr, Hannah Cummins, David Hackett, Ellen Healy, Nina Kulczycka, Niall Lang, Luke Madden, Lynne McHugh, Ivana Pyne, Ciara Varley, Niamh Harkin, Ronan Meade, Grace O'Donnell, Bra
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.02.13.637616

BrainAGE: Revisited and reframed machine learning workflow

Author(s): Polona Kalc; Robert Dahnke; Felix Hoffstaedter; Christian Gaser
Published in: Crossref, Issue 1, 2024, ISSN 2073-4409
Publisher: MDPI
DOI: 10.1101/2022.11.21.517386

Membrane-based microfluidic systems for medical and biological applications.

Author(s): Calzuola, S.T., Newman, G., Feaugas, T., Perrault, C.M., Blondé, J.-B., Roy, E., et al.
Published in: Lab on a Chip, Issue 24, 2024, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4lc00251b

Bacterial peptidoglycans as novel signaling molecules from microbiota to brain

Author(s): Giorgia Tosoni, Mirko Conti, Rochellys Diaz Heijtz
Published in: Current Opinion in Pharmacology, Issue 48, 2022, Page(s) 107-113, ISSN 1471-4892
Publisher: Elsevier BV
DOI: 10.1016/j.coph.2019.08.003

Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson’s Disease

Author(s): Caroline Ran, Karin Wirdefeldt, Olof Sydow, Per Svenningsson, Rochellys Diaz Heijtz
Published in: Parkinson's Disease, Issue 2023, 2023, Page(s) 1-7, ISSN 2042-0080
Publisher: Hindawi Publishing Corporation
DOI: 10.1155/2023/6502727

Development of Polymer-Encapsulated, Amine-Functionalized Zinc Ferrite Nanoparticles as MRI Contrast Agents

Author(s): Ágnes M. Ilosvai, László Forgách, Noémi Kovács, Fatemeh Heydari, Krisztián Szigeti, Domokos Máthé, Ferenc Kristály, Lajos Daróczi, Zoltán Kaleta, Béla Viskolcz, Miklós Nagy, László Vanyorek
Published in: International Journal of Molecular Sciences, Issue 24, 2025, Page(s) 16203, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216203

Beyond the Individual-A Scoping Review and Bibliometric Mapping of Ecological Determinants of Eating Behavior in Older Adults.

Author(s): Montez De Sousa ÍR, Bergheim I and Brombach C
Published in: Public Health Reviews, Issue 21076952, 2022, ISSN 2107-6952
Publisher: Frontiers
DOI: 10.3389/phrs.2022.1604967

Brain Macro-Structural Alterations in Aging Rats: A Longitudinal Lifetime Approach

Author(s): Sidra Gull; Christian Gaser; Karl-Heinz Herrmann; Anja Urbach; Marcus Boehme; Samia Afzal; Jürgen R. Reichenbach; Otto W. Witte; Silvio Schmidt
Published in: Cells, Issue 12(3), 2023, Page(s) 432, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells12030432

Nonlinear DNA methylation trajectories in aging male mice

Author(s): Maja Olecka; Alena van Bömmel; Lena Best; Madlen Haase; Silke Foerste; Konstantin Riege; Thomas Dost; Stefano Flor; Otto W. Witte; Sören Franzenburg; Marco Groth; Björn von Eyss; Christoph Kaleta; Christiane Frahm; Steve Hoffmann
Published in: "http://lobid.org/resources/99370674014306441#!, 15(1):3074", Issue 15, 2024, Page(s) 3074, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-47316-2

Radiolabeling of Platelets with 99mTc-HYNIC-Duramycin for In Vivo Imaging Studies

Author(s): Keresztély Merkel; Dávid Szöllősi; Ildikó Horváth; Bálint Jezsó; Zsolt Baranyai; Krisztián Szigeti; Zoltán Varga; Imre Hegedüs; Parasuraman Padmanabhan; Balázs Gulyás; Ralf Bergmann; Domokos Máthé
Published in: International Journal of Molecular Sciences, Issue 24(23), 2023, Page(s) 17119, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317119

Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project.

Author(s): Garo-Pascual, M., Gaser, C., Zhang, L., Tohka, J., Medina, M., & Strange, B. A.
Published in: The Lancet Healthy Longevity, Issue 4(8), 2023, Page(s) e374–e385, ISSN 2666-7568
Publisher: Elsevier BV
DOI: 10.1016/s2666-7568(23)00079-x

Characterization of neurocognitive deficits in patients with post-COVID-19 syndrome: persistence, patients' complaints, and clinical predictors.

Author(s): Kozik, V., Reuken, P., Utech, I., Gramlich, J., Stallmach, Z., Demeyere, N., Rakers, F., Schwab, M., Stallmach, A., & Finke, K.
Published in: Frontiers in Psychology, Issue 14, 2023, Page(s) 1233144, ISSN 1664-1078
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyg.2023.1233144

Solvothermal synthesis of polyvinyl pyrrolidone encapsulated, amine-functionalized copper ferrite and its use as a magnetic resonance imaging contrast agent

Author(s): Fatemeh Heydari, Ágnes M. Ilosvai, Noémi Kovács, Domokos Máthé, Ferenc Kristály, Lajos Daróczi, Zoltán Kaleta, Béla Viskolcz, Miklós Nagy, László Vanyorek, László Forgách, Krisztián Szigeti
Published in: PLOS ONE, Issue 20, 2025, Page(s) e0316221, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0316221

Microbial Abundances Retrieved from Sequencing data - Automated NCBI Taxonomy (MARS): A pipeline to create relative microbial abundance data for the Microbiome Modelling Toolbox and utilising homosynonyms for efficient mapping to resources.

Author(s): Hulshof T, Nap B, Martinelli F, Thiele I
Published in: Bioinformatics Advances, Issue 4(1), 2024, Page(s) vbae068, ISSN 2635-0041
Publisher: Oxford University Press
DOI: 10.1093/bioadv/vbae068

Metformin-induced changes in the gut microbiome and plasma metabolome are associated with cognition in men

Author(s): Marisel Rosell-Díaz, Anna Petit-Gay, Clàudia Molas-Prat, Laura Gallardo-Nuell, Lluís Ramió-Torrentà, Josep Garre-Olmo, Vicente Pérez-Brocal, Andrés Moya, Mariona Jové, Reinald Pamplona, Josep Puig 8, Rafael Ramos, Fredrik Bäckhed, Jordi Mayneris-Perxachs, José Manuel Fernández-Real
Published in: Metabolism, 2024, ISSN 0026-0495
Publisher: Elsevier BV
DOI: 10.1016/j.metabol.2024.155941

Evaluation of inter- and intra-variability in gut health markers in healthy adults using an optimised faecal sampling and processing method

Author(s): Kirsten Kruger, Yoou Myeonghyun, Nicky van der Wielen, Dieuwertje E. Kok, Guido J. Hooiveld, Shohreh Keshtkar, Marlies Diepeveen-de Bruin, Michiel G. J. Balvers, Mechteld Grootte-Bromhaar, Karin Mudde, Nhien T. H. N. Ly, Yannick Vermeiren, Lisette C. P. G. M. de Groot, Ric C. H. de Vos, Gerard Bryan Gonzales, Wilma T. Steegenga, Mara P. H. van Trijp
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-75477-z

Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions

Author(s): Annette Brandt, Franziska Kromm, Angélica Hernández-Arriaga, Inés Martínez Sánchez, Haktan Övül Bozkir, Raphaela Staltner, Anja Baumann, Amélia Camarinha-Silva, Rochellys Diaz Heijtz, Ina Bergheim
Published in: Cells, 2023, ISSN 2073-4409
Publisher: mdpi
DOI: 10.3390/cells12172153

A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites

Author(s): Almut Heinken, Timothy Otto Hulshof, Bram Nap, Filippo Martinelli, Arianna Basile, Amy O’Brolchain, Neil Francis O’Sullivan, Celine Gallagher, Eimer Magee, Francesca McDonagh, Ian Lalor, Maeve Bergin, Phoebe Evans, Rachel Daly, Ronan Farrell, Rose Mary Delaney, Saoirse Hill, Saoirse Roisin McAuliffe, Trevor Kilgannon, Ronan M.T. Fleming, Cyrille C. Thinnes, Ines Thiele
Published in: Cell Systems, Issue 16, 2025, Page(s) 101196, ISSN 2405-4712
Publisher: Cell Press
DOI: 10.1016/j.cels.2025.101196

Maternal peptidoglycan overexposure during late pregnancy alters neurodevelopment and behavior in juvenile offspring

Author(s): Inés Martínez Sánchez, Julia Spielbauer, Rochellys Diaz Heijtz
Published in: Brain, Behavior, and Immunity, Issue 127, 2025, Page(s) 96-102, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2025.03.014

A perspective on brain-age estimation and its clinical promise

Author(s): Christian Gaser, Polona Kalc, James H. Cole
Published in: Nature Computational Science, Issue 4, 2024, Page(s) 744-751, ISSN 2662-8457
Publisher: nature
DOI: 10.1038/s43588-024-00659-8

Cross-National Survey About Nutrition and Nutrition Communication Among Older Adults Aged 60 Years and Above

Author(s): Julia Juber, Íris Rafaela Montez De Sousa, Johanna Kreher, Christel Rademacher, Christine Brombach
Published in: Nutrients, Issue 17, 2025, Page(s) 315, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu17020315

Abstracts

Author(s): Rosell-Díaz M
Published in: European Journal of Clinical Investigation, Issue 54, 2024, Page(s) """Vol. 54, Supplement 1, June 2024""", ISSN 0014-2972
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/eci.14220

Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments.

Author(s): Nele Demeyere; Marleen Haupt; Sam S Webb; Lea Strobel; Elise Milosevich; Margaret Jane Moore; Hayley Wright; Kathrin Finke; Mihaela Duta
Published in: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021), Issue 2, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.31234/osf.io/b2vgc

Quantitative Biodistribution of OMVs Using SPECT/CT Imaging with HYNIC-Duramycin Radiolabeling

Author(s): Dávid Szöllősi, Polett Hajdrik, Hedvig Tordai, Ralf Bergmann, Ildikó Horváth, Judith Mihály, Anikó Gaál, Bálint Jezsó, Kanni Das Shailaja, Tamás Felföldi, Parasuraman Padmanabhan, Balázs Zoltán Gulyás, Domokos Máthé, Zoltán Varga, Krisztián Szigeti
Published in: ACS Omega, Issue 9, 2024, Page(s) 42808-42813, ISSN 2470-1343
Publisher: ACS Publications
DOI: 10.1021/acsomega.4c04632

Low bone mineral density is associated with gray matter volume decrease in UK Biobank.

Author(s): Kalc, P., Dahnke, R., Hoffstaedter, F., & Gaser, C.
Published in: Frontiers in aging neuroscience, Issue 15, 2023, Page(s) 287304, ISSN 1663-4365
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnagi.2023.1287304

Soluble receptors for advanced glycation endproducts are predictors of insulin sensitivity and affected by weight loss

Author(s): José María Moreno-Navarrete, Yenny Leal, Marisel Rosell-Díaz, José Manuel Fernández-Real
Published in: Nutrition & Diabetes, Issue 14, 2024, Page(s) 88, ISSN 2044-4052
Publisher: Nature Publishing Group
DOI: 10.1038/s41387-024-00345-8

A hypoarousal model of neurological post-COVID syndrome: the relation between mental fatigue, the level of central nervous activation and cognitive processing speed

Author(s): Eva Maria Martin, Sven Rupprecht, Simon Schrenk, Fabian Kattlun, Isabelle Utech, Monique Radscheidt, Stefan Brodoehl, Matthias Schwab, Philipp A. Reuken, Andreas Stallmach, Thomas Habekost & Kathrin Finke
Published in: Journal of Neurology, 2023, ISSN 1432-1459
Publisher: SPRINGER HEIDELBERG
DOI: 10.1007/s00415-023-11819-7

Visual processing speed is linked to functional connectivity between right frontoparietal and visual networks

Author(s): Svenja Küchenhoff, Christian Sorg, Sebastian C. Schneider, Oliver Kohl, Hermann J. Müller, Natan Napiórkowski, Aurore Menegaux, Kathrin Finke, Adriana L. Ruiz-Rizzo
Published in: European Journal of Neuroscience, Issue 53, 2021, Page(s) 3362–3377, ISSN 1460-9568
Publisher: Wiley
DOI: 10.1111/ejn.15206

Young microbiota rejuvenates the aging brain

Author(s): Rochellys Diaz Heijtz, Ayoze Gonzalez-Santana, Jon D. Laman
Published in: Nature Aging, Issue 1, 2022, Page(s) 625-627, ISSN 2662-8465
Publisher: Springer Nature
DOI: 10.1038/s43587-021-00100-z

Lower serum ferritin levels are associated with worse cognitive performance in aging

Author(s): Marisel Rosell-Díaz, Elena Santos-González, Anna Motger-Albertí, Laura Gallardo-Nuell, María Arnoriaga-Rodríguez, Clàudia Coll-Martínez, Lluís Ramió-Torrentà, Josep Garre-Olmo, Josep Puig, Rafael Ramos, Jordi Mayneris-Perxachs, José Manuel Fernández-Real
Published in: The Journal of nutrition, health and aging, 2024, ISSN 1279-7707
Publisher: SERDI Publisher
DOI: 10.1016/j.jnha.2024.100190

Long COVID is associated with severe cognitive slowing: a multicentre cross-sectional study

Author(s): Sijia Zhao, Eva Maria Martin, Philipp A. Reuken, Anna Scholcz, Akke Ganse-Dumrath, Annie Srowig, Isabelle Utech, Valeska Kozik, Monique Radscheidt, Stefan Brodoehl, Andreas Stallmach, Matthias Schwab, Emily Fraser, Kathrin Finke, Masud Husain
Published in: eClinicalMedicine, Issue 68, 2024, Page(s) 102434, ISSN 2589-5370
Publisher: The Lancet
DOI: 10.1016/j.eclinm.2024.102434

Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain.

Author(s): Ederer ML, Günther M, Best L, Lindner J, Kaleta C, Witte OW, Simon R, Frahm C
Published in: Cells, Issue 20734409, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11030566

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine.

Author(s): Heinken, A., Hertel, J., Acharya, G., Ravcheev, D. A., Nyga, M., Okpala, O. E., Hogan, M., Magnúsdóttir, S., Martinelli, F., Nap, B., Preciat, G., Edirisinghe, J. N., Henry, C. S., Fleming, R. M. T., & Thiele, I.
Published in: Nature biotechnology, Issue 41(9), 2023, Page(s) 1320–1331, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/s41587-022-01628-0

Parkinson’s Disease and the Metal–Microbiome–Gut–Brain Axis: A Systems Toxicology Approach

Author(s): Forero-Rodríguez, Josephs-Spaulding, Flor, Pinzón, Kaleta
Published in: Antioxidants, Issue 11(1), 2022, ISSN 2076-3921
Publisher: MDPI
DOI: 10.3390/antiox11010071

Targeting microbial metabolites to treat autism

Author(s): Rochellys Diaz Heijtz, Pierre Gressens, Jonathan R. Swann
Published in: Nature Medicine, Issue 28, 2022, Page(s) 448-450, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-022-01711-8

Effect of methanol fixation on single-cell RNA sequencing of the murine dentate gyrus

Author(s): Marta Sánchez-Carbonell, Patricia Jiménez Peinado, Cathrin Bayer-Kaufmann, Jean-Christopher Hennings, Yvonne Hofmann, Silvio Schmidt, Otto W. Witte, Anja Urbach
Published in: Frontiers in Molecular Neuroscience, Issue 16, 2023, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2023.1223798

Gut microbiota links to serum ferritin and cognition

Author(s): Marisel Rosell-Díaza,Elena Santos-González,Anna Motger-Albertí,Lluís Ramió-Torrentà,Josep Garre-Olmo,Vicente Pérez-Brocal,Andrés Moya,Mariona Jové,Reinald Pamplona,Josep Puig,Rafael Ramos,José Manuel Fernández-Real
Published in: Gut microbes, 2023, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2023.2290318

Restoring Age-Related Cognitive Decline through Environmental Enrichment: A Transcriptomic Approach

Author(s): Silvio Schmidt, Madlen Haase, Lena Best, Marco Groth, Julia Lindner, Otto W Witte, Christoph Kaleta, Christiane Frahm
Published in: Cells, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11233864

Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia.

Author(s): Ruiz-Rizzo, A. L., Finke, K., Damoiseaux, J. S., Bartels, C., Buerger, K., Cosma, N. C., Dechent, P., Dobisch, L., Ewers, M., Fliessbach, K., Frommann, I., Glanz, W., Goerss, D., Hetzer, S., Incesoy, E. I., Janowitz, D., Kilimann, I., Laske, C., van Lent, D. M., Munk, M. H. J., … Rauchmann, B. S.
Published in: Neurobiology of Aging, Issue 136, 2024, Page(s) 99-110, ISSN 0197-4580
Publisher: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2024.01.012

Microbiota profiling in aging-associated inflammation and liver degeneration

Author(s): Anja Baumann, Angélica Hernández-Arriaga, Annette Brandt, Victor Sánchez, Anika Nier, Finn Jung, Richard Kehm, Annika Höhn, Tilman Grune, Christiane Frahm, Otto Wilhelm Witte, Amélia Camarinha-Silva, Ina Bergheim
Published in: International Journal of Medical Microbiology, Issue 311/4, 2021, Page(s) 151500, ISSN 1438-4221
Publisher: Elsevier BV
DOI: 10.1016/j.ijmm.2021.151500

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Author(s): Dávid Szöllősi; Polett Hajdrik; Hedvig Tordai; Ildikó Horváth; Dániel S. Veres; Bernadett Gillich; Kanni Das Shailaja; László Smeller; Ralf Bergmann; Michael Bachmann; Judith Mihály; Anikó Gaál; Bálint Jezsó; Balázs Barátki; Dorottya Kövesdi; Szilvia Bősze; Ildikó Szabó; Tamás Felföldi; Erzsébet Oszwald; Parasuraman Padmanabhan; Balázs Zoltán Gulyás; Nazha Hamdani; Domokos
Published in: Nature: Scientific Reports, Issue 2, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Metformin, Cognitive Function, and Changes in the Gut Microbiome

Author(s): Marisel Rosell-Díaz, José Manuel Fernández-Real
Published in: Endocrine reviews, 2023, ISSN 0163-769X
Publisher: The Endocrine Society
DOI: 10.1210/endrev/bnad029

CAT: a computational anatomy toolbox for the analysis of structural MRI data

Author(s): Christian Gaser, Robert Dahnke, Paul M Thompson, Florian Kurth, Eileen Luders, null the Alzheimer's Disease Neuroimaging Initiative
Published in: GigaScience, Issue 13, 2024, ISSN 2047-217X
Publisher: Oxford Academics
DOI: 10.1093/gigascience/giae049

Impact of an Online Guided Physical Activity Training on Cognition and Gut-Brain Axis Interactions in Older Adults: Protocol of a Randomized Controlled Trial

Author(s): Schrenk, S., Brodoehl, S., Flor, S., Frahm, C., Gaser, C., Abou-Hamdan, R., Herbsleb, M., Kaleta, C., Kattlun, F., Müller, H.J., Puta, C., Radscheidt, M., Ruiz-Rizzo, A.L., Saraei, T., Scherag, A., Steidten, T., Witte, O.W. and Finke, K.
Published in: Frontiers in Aging Neuroscience, 2023, ISSN 1663-4365
Publisher: Frontiers Research Foundation

Bacterial peptidoglycan signalling in microglia: Activation by MDP via the NF-κB/MAPK pathway

Author(s): Julia Spielbauer, Elliot J. Glotfelty, Heela Sarlus, Robert A. Harris, Rochellys Diaz Heijtz, Tobias E. Karlsson
Published in: Brain, Behavior, and Immunity, Issue 121, 2024, Page(s) 43-55, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2024.06.027

Persistent cognitive slowing in post-COVID patients: longitudinal study over 6 months.

Author(s): Martin, E. M., Srowig, A., Utech, I., Schrenk, S., Kattlun, F., Radscheidt, M., Brodoehl, S., Bublak, P., Schwab, M., Geis, C., Besteher, B., Reuken, P. A., Stallmach, A., & Finke, K.
Published in: Journal of Neurology, Issue 271, 2023, Page(s) 45-58, ISSN 1432-1459
Publisher: Springer
DOI: 10.1007/s00415-023-12069-3

Long COVID is associated with severe cognitive slowing: a multicentre cross-sectional study.

Author(s): Zhao, S., Martin, E. M., Reuken, P. A., Scholcz, A., Ganse-Dumrath, A., Srowig, A., Utech, I., Kozik, V., Radscheidt, M., Brodoehl, S., Stallmach, A., Schwab, M., Fraser, E., Finke, K., & Husain, M.
Published in: eClinicalMedicine, Issue 68, 2024, Page(s) 102434, ISSN 2589-5370
Publisher: Elsevier BV
DOI: 10.1016/j.eclinm.2024.102434

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

Author(s): Annette Brandt; Anja Baumann; Angélica Hernández-Arriaga; Finn Jung; Anika Nier; Raphaela Staltner; Dragana Rajcic; Christian Schmeer; Otto W. Witte; Barbara Wessner; Bernhard Franzke; Karl-Heinz Wagner; Amélia Camarinha-Silva; Ina Bergheim
Published in: Redox Biology, 2022, ISSN 2213-2317
Publisher: Elsevier BV
DOI: 10.1016/j.redox.2022.102528

DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection

Author(s): Ángela del Castillo-Izquierdo; José María Moreno-Navarrete; Jessica Latorre; María Arnoriaga-Rodríguez; Marta Ballanti; Giovanni Monteleone; Omero Alessandro Paoluzi; Geltrude Mingrone; Josep Puig; Rafael Ramos; Josep Garre-Olmo; Mariona Jové; Reinald Pamplona; Manuel Portero-Otín; Joaquim Sol; Philippe Lefebvre; Bart Staels; Massimo Federici; José Manuel Fernández-Real; Jordi Mayneris-Pe
Published in: Antioxidants, Issue 12, 2022, Page(s) 11(11):2177, ISSN 2076-3921
Publisher: MDPI
DOI: 10.3390/antiox11112177

Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism

Author(s): Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs
Published in: Gut Microbes, Issue 17, 2025, Page(s) 2455506, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2025.2455506

Bidirectional relationships between the gut microbiome and sexual traits

Author(s): Del Castillo-Izquierdo A, Mayneris-Perxachs J, Fernández-Real JM.
Published in: American Journal of Physiology-Cell Physiology, Issue Vol. 322, No 6, 1 June 2022, 2022, Page(s) C1223-C1229, ISSN 1522-1563
Publisher: American Physiological Society
DOI: 10.1152/ajpcell.00116.2022

Metabolic modeling reveals the aging-associated decline of host-microbiome metabolic interactions in mice

Author(s): Lena Best, Thomas Dost, Daniela Esser, Stefano Flor, Madlen Haase, A. Samer Kadibalban, Georgios Marinos, Alesia Walker, Johannes Zimmermann, Rowena Simon, Silvio Schmidt, Jan Taubenheim, Sven Kunzel, Robert Hasler, Marco Groth, Silvio Waschina, Otto W. Witte, Phillipe Schmitt-Kopplin, John F. Baines, Christiane Frahm, Christoph Kaleta
Published in: BiorXiv preprint, 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.03.28.587009

Microbial Regulation Of 3-hydroxyanthranilic Acid Impacts Attention

Author(s): Andrea Fumagalli
Published in: European Journal of Clinical Investigation, Issue Vol. 54, Supplement 1, June 2024, 2024
Publisher: Blackwell Publishing Inc.

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