Gut-brain-axis: Targets for improvement of cognition in the elderly

Resultado final

Data management plan

A data management plan will be drawn up.

Project website and press release SmartAge opening

The project website will be opened and there will be a press release with respect to SmartAge opening

Kick-off Meeting, Consortium agreement

The Kick off meeting with all participants will take place and the CA will be signed

Publicaciones

BrainAGE: Revisited and reframed machine learning workflow

Autores: Polona Kalc; Robert Dahnke; Felix Hoffstaedter; Christian Gaser
Publicado en: Crossref, Edición 1, 2024, ISSN 2073-4409
Editor: MDPI
DOI: 10.1101/2022.11.21.517386

Beyond the Individual-A Scoping Review and Bibliometric Mapping of Ecological Determinants of Eating Behavior in Older Adults.

Autores: Montez De Sousa ÍR, Bergheim I and Brombach C
Publicado en: Public Health Reviews, Edición 21076952, 2022, ISSN 2107-6952
Editor: Frontiers
DOI: 10.3389/phrs.2022.1604967

Brain Macro-Structural Alterations in Aging Rats: A Longitudinal Lifetime Approach

Autores: Sidra Gull; Christian Gaser; Karl-Heinz Herrmann; Anja Urbach; Marcus Boehme; Samia Afzal; Jürgen R. Reichenbach; Otto W. Witte; Silvio Schmidt
Publicado en: Cells, Edición 12(3), 2023, Página(s) 432, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells12030432

Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions

Autores: Annette Brandt, Franziska Kromm, Angélica Hernández-Arriaga, Inés Martínez Sánchez, Haktan Övül Bozkir, Raphaela Staltner, Anja Baumann, Amélia Camarinha-Silva, Rochellys Diaz Heijtz, Ina Bergheim
Publicado en: Cells, 2023, ISSN 2073-4409
Editor: mdpi
DOI: 10.3390/cells12172153

Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments.

Autores: Nele Demeyere; Marleen Haupt; Sam S Webb; Lea Strobel; Elise Milosevich; Margaret Jane Moore; Hayley Wright; Kathrin Finke; Mihaela Duta
Publicado en: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021), Edición 2, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.31234/osf.io/b2vgc

A hypoarousal model of neurological post-COVID syndrome: the relation between mental fatigue, the level of central nervous activation and cognitive processing speed

Autores: Eva Maria Martin, Sven Rupprecht, Simon Schrenk, Fabian Kattlun, Isabelle Utech, Monique Radscheidt, Stefan Brodoehl, Matthias Schwab, Philipp A. Reuken, Andreas Stallmach, Thomas Habekost & Kathrin Finke
Publicado en: Journal of Neurology, 2023, ISSN 1432-1459
Editor: SPRINGER HEIDELBERG
DOI: 10.1007/s00415-023-11819-7

Visual processing speed is linked to functional connectivity between right frontoparietal and visual networks

Autores: Svenja Küchenhoff, Christian Sorg, Sebastian C. Schneider, Oliver Kohl, Hermann J. Müller, Natan Napiórkowski, Aurore Menegaux, Kathrin Finke, Adriana L. Ruiz-Rizzo
Publicado en: European Journal of Neuroscience, Edición 53, 2021, Página(s) 3362–3377, ISSN 1460-9568
Editor: Wiley
DOI: 10.1111/ejn.15206

Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain.

Autores: Ederer ML, Günther M, Best L, Lindner J, Kaleta C, Witte OW, Simon R, Frahm C
Publicado en: Cells, Edición 20734409, 2021, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells11030566

Parkinson’s Disease and the Metal–Microbiome–Gut–Brain Axis: A Systems Toxicology Approach

Autores: Forero-Rodríguez, Josephs-Spaulding, Flor, Pinzón, Kaleta
Publicado en: Antioxidants, Edición 11(1), 2022, ISSN 2076-3921
Editor: MDPI
DOI: 10.3390/antiox11010071

Restoring Age-Related Cognitive Decline through Environmental Enrichment: A Transcriptomic Approach

Autores: Silvio Schmidt, Madlen Haase, Lena Best, Marco Groth, Julia Lindner, Otto W Witte, Christoph Kaleta, Christiane Frahm
Publicado en: Cells, 2022, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells11233864

Microbiota profiling in aging-associated inflammation and liver degeneration

Autores: Anja Baumann, Angélica Hernández-Arriaga, Annette Brandt, Victor Sánchez, Anika Nier, Finn Jung, Richard Kehm, Annika Höhn, Tilman Grune, Christiane Frahm, Otto Wilhelm Witte, Amélia Camarinha-Silva, Ina Bergheim
Publicado en: International Journal of Medical Microbiology, Edición 311/4, 2021, Página(s) 151500, ISSN 1438-4221
Editor: Elsevier BV
DOI: 10.1016/j.ijmm.2021.151500

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Autores: Dávid Szöllősi; Polett Hajdrik; Hedvig Tordai; Ildikó Horváth; Dániel S. Veres; Bernadett Gillich; Kanni Das Shailaja; László Smeller; Ralf Bergmann; Michael Bachmann; Judith Mihály; Anikó Gaál; Bálint Jezsó; Balázs Barátki; Dorottya Kövesdi; Szilvia Bősze; Ildikó Szabó; Tamás Felföldi; Erzsébet Oszwald; Parasuraman Padmanabhan; Balázs Zoltán Gulyás; Nazha Hamdani; Domokos
Publicado en: Nature: Scientific Reports, Edición 2, 2023, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Metformin, Cognitive Function, and Changes in the Gut Microbiome

Autores: Marisel Rosell-Díaz, José Manuel Fernández-Real
Publicado en: Endocrine reviews, 2023, ISSN 0163-769X
Editor: The Endocrine Society
DOI: 10.1210/endrev/bnad029

Impact of an Online Guided Physical Activity Training on Cognition and Gut-Brain Axis Interactions in Older Adults: Protocol of a Randomized Controlled Trial

Autores: Schrenk, S., Brodoehl, S., Flor, S., Frahm, C., Gaser, C., Abou-Hamdan, R., Herbsleb, M., Kaleta, C., Kattlun, F., Müller, H.J., Puta, C., Radscheidt, M., Ruiz-Rizzo, A.L., Saraei, T., Scherag, A., Steidten, T., Witte, O.W. and Finke, K.
Publicado en: Frontiers in Aging Neuroscience, 2023, ISSN 1663-4365
Editor: Frontiers Research Foundation

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

Autores: Annette Brandt; Anja Baumann; Angélica Hernández-Arriaga; Finn Jung; Anika Nier; Raphaela Staltner; Dragana Rajcic; Christian Schmeer; Otto W. Witte; Barbara Wessner; Bernhard Franzke; Karl-Heinz Wagner; Amélia Camarinha-Silva; Ina Bergheim
Publicado en: Redox Biology, 2022, ISSN 2213-2317
Editor: Elsevier BV
DOI: 10.1016/j.redox.2022.102528

DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection

Autores: Ángela del Castillo-Izquierdo; José María Moreno-Navarrete; Jessica Latorre; María Arnoriaga-Rodríguez; Marta Ballanti; Giovanni Monteleone; Omero Alessandro Paoluzi; Geltrude Mingrone; Josep Puig; Rafael Ramos; Josep Garre-Olmo; Mariona Jové; Reinald Pamplona; Manuel Portero-Otín; Joaquim Sol; Philippe Lefebvre; Bart Staels; Massimo Federici; José Manuel Fernández-Real; Jordi Mayneris-Pe
Publicado en: Antioxidants, Edición 12, 2022, Página(s) 11(11):2177, ISSN 2076-3921
Editor: MDPI
DOI: 10.3390/antiox11112177

Bidirectional relationships between the gut microbiome and sexual traits

Autores: Del Castillo-Izquierdo A, Mayneris-Perxachs J, Fernández-Real JM.
Publicado en: American Journal of Physiology-Cell Physiology, Edición Vol. 322, No 6, 1 June 2022, 2022, Página(s) C1223-C1229, ISSN 1522-1563
Editor: American Physiological Society
DOI: 10.1152/ajpcell.00116.2022

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