Best chemical risk assessment professionals for maximum Ecosystem Services benefit

Project Information

PRORISK

Grant agreement ID: 859891

DOI

10.3030/859891

Project closed

EC signature date 27 March 2020

Start date 1 April 2020

End date 31 March 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 4 024 982,52

EU contribution

€ 4 024 982,52

Coordinated by

Masarykova univerzita
Czechia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (24)

Outreach activities report 2

Outreach activities report

Tools for evaluating chemical effects on interactions between multiple ecosystem functions driving ecosystem service delivery
Tools for assessing ecosystem service delivery effects at different temporal and spatial scales
Integration of multiple stressor impacts and translation of AOPs to population level
Scientific Newsletter 4

Scientific Newsletter

Outreach activities report 1

Outreach activities report

Guidance document on chemical analysis of selected contaminants
Conceptual AOPs proposed and submitted to AOP-Wiki

Conceptual AOPs proposed and submitted to AOPWiki

Status report on results from experimental and modelling studies on population-level outcomes

Status report on results from experimental and modelling studies on populationlevel outcomes

Paper on linkage of chemical-biological interaction and molecular initiating event

Paper on linkage of chemicalbiological interaction and molecular initiating event

Article in CORDIS magazine
Review on integration of AOP approaches in risk assessment of chemicals at individual and population levels
Tools/protocols for characterization of relevant MIE, KEs and AOs

Toolsprotocols for characterization of relevant MIE KEs and AOs

Tools for assessing chemical impact on service providing units and ecosystem functions providing ecosystem services
Current ecotoxicological methods for assessing risk of chemicals and other stressors for ecosystem service delivery
Scientific Newsletter 3

Scientific Newsletter

Scientific Newsletter 1

Scientific Newsletter

Scientific Newsletter 2

Scientific Newsletter

Developed qAOPs and refined AOPs submitted to OECD-EAMST expert evaluation
Outreach activities report 3

Outreach activities report

Review paper on toxicokinetics and biotransformation of selected contaminants including employment of imaging techniques
Paper on effects of natural stressors on toxicokinetics of selected model chemicals in PRORISK test organisms
Guidance for combining socio-economic, ecosystem services, and risk assessment information to inform risk management
Tools for facilitating translation of conventional ecotoxicological measurement to ecosystem service-relevant assessment endpoints

Websites, patent fillings, videos etc. (1)

Project website: project website (intra and internet) up and running

Other (1)

Workshop with stakeholders to promote implementation of PRORISK developed tools

Publications

Peer reviewed articles (23)

Endocrine disrupting potential of replacement flame retardants-Review of current knowledge for nuclear receptors associated with reproductive outcomes

Author(s): Lola Bajard, Chander K. Negi, Vicente Mustieles, Lisa Melymuk, Stéphane Jomini, Johanna Barthelemy-Berneron, Mariana F. Fernandez, Ludek Blaha
Published in: Environment International, Issue 153, 2021, Page(s) 1-12, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106550

Age and Synchronization of Daphnia magna Affect Sensitivityto Teflubenzuron in Acute Standardized Toxicity Tests

Author(s): Simon Schmid, Jan T. Rundberget, You Song, Knut Erik Tollefsen
Published in: Environmental Toxicology and Chemistry, Issue 42/8, 2023, Page(s) 1806-1815, ISSN 0730-7268
Publisher: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5688

To Split or Not to Split: Characterizing Chemical Pollution Impacts in Aquatic Ecosystems with Species Sensitivity Distributions for Specific Taxonomic Groups

Author(s): Susan A. Oginah, Leo Posthuma, Jaap Slootweg, Michael Hauschild, Peter Fantke
Published in: Environmental Science & Technology, Issue 57/39, 2023, Page(s) 14526-14538, ISSN 1520-5851
Publisher: American Chemical Society
DOI: 10.1021/acs.est.3c04968

Soil dwelling springtails are resilient to extreme drought in soil, but their reproduction is highly sensitive to small decreases in soil water potential

Author(s): Yang Wang, Stine Slotsbo and Martin Holmstrup
Published in: Geoderma, Issue Volume 421, 2022, Page(s) 115913, ISSN 0016-7061
Publisher: Elsevier BV
DOI: 10.1016/j.geoderma.2022.115913

Replacement Flame-Retardant 2-Ethylhexyldiphenyl Phosphate (EHDPP) Disrupts Hepatic Lipidome: Evidence from Human 3D Hepatospheroid Cell Culture

Author(s): Chander K. Negi; Darshak Gadara; Jiri Kohoutek; Lola Bajard; Zdeněk Spáčil; Ludek Blaha
Published in: Environmental Science and Technology, Issue 57, 2023, Page(s) 2006-2018, ISSN 1520-5851
Publisher: ACS PUBLICATIONS
DOI: 10.1021/acs.est.2c03998

An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis

Author(s): Chander K. Negi, Lola Bajard, Jiri Kohoutek, Ludek Blaha
Published in: Environmental Pollution, Issue 289, 2021, Page(s) 1-11, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2021.117855

Toward harmonizing global pesticide regulations for surface freshwaters in support of protecting human health

Author(s): Zijian Li, Peter Fantke
Published in: Journal of Environmental Management, Issue 301, 2022, Page(s) 113909, ISSN 0301-4797
Publisher: Academic Press
DOI: 10.1016/j.jenvman.2021.113909

Battery of In Vitro Bioassays: A Case Study for the Cost-Effective and Effect-Based Evaluation of Wastewater Effluent Quality

Author(s): Nikiforos Alygizakis, Kelsey Ng, Niki Maragou, Sylvana Alirai, Peter Behnisch, Harrie Besselink, Peter Oswald, Lubos Cirka, Nikolaos S. Thomaidis, Jaroslav Slobodnik
Published in: Water, Issue Volume 19, 2023, Page(s) 619, ISSN 2073-4441
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/w15040619

A trait-based approach to determine the risks of Zn to the overall health status of native fish species Barbus meridionalis

Author(s): Amina Khalid, Cristina Galobart, Francesc Rubio-Gracia, Guluzar Atli, Helena Guasch, Anna Vila-Gispert
Published in: Aquatic Toxicology, Issue 262, 2023, Page(s) 106661, ISSN 0166-445X
Publisher: Elsevier BV
DOI: 10.1016/j.aquatox.2023.106661

Low soil Moisture Slows Uptake and Elimination Rates of Phenanthrene in Springtails

Author(s): Yang Wang, Stine Slotsbo, Peter B Sørensen, Martin Holmstrup
Published in: Bulletin of Environmental Contamination and Toxicology, Issue 112/25, 2024, ISSN 0007-4861
Publisher: Springer Verlag
DOI: 10.1007/s00128-024-03854-5

Increased daily temperature fluctuations exacerbate the toxicity of phenanthrene in Enchytraeus albidus (Enchytraeidae)

Author(s): Wencai Dai, Stine Slotsbo, Liyan Xie, Yang Wang, Christian Damgaard, Martin Holmstrup
Published in: Science of The Total Environment, Issue 873, 2023, Page(s) 162403, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162403

Wide-Scope Target and Suspect Screening of Antibiotics in Effluent Wastewater from Wastewater Treatment Plants in Europe

Author(s): Kelsey Ng ,Nikiforos A. Alygizakis, Nikolaos S. Thomaidis, Jaroslav Slobodnik
Published in: Antibiotics, Issue 12, 2023, Page(s) 100, ISSN 2079-6382
Publisher: MDPI
DOI: 10.3390/antibiotics12010100

Antiandrogenic activity of novel flame retardants inmixtures: newly identified contribution from tris(2,3-dibromopropyl) isocyanurate (TDBP-TAZTO).

Author(s): Lola Bajard, Hana Vespalcová, Chander K. Negi, Jiří Kohoutek, Luděk Bláha, Iva Sovadinová
Published in: Chemosphere, Issue volume 341, 2023, Page(s) 1-11, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.140004

Linking freshwater ecotoxicity to damage on ecosystem services in life cycle assessment

Author(s): Susan A. Oginah , Leo Posthuma, Lorraine Maltby, Michael Hauschild Peter Fantke
Published in: Environment International, Issue Volume 171, 2023, Page(s) 107705, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107705

Influence of Soil Moisture on Bioaccumulation, Growth, and Recruitment of Folsomia candida Exposed to Phenanthrene-Polluted Soil

Author(s): Yang Wang, Stine Slotsbo, Christian Frølund Damgaard, and Martin Holmstrup
Published in: Environmental Science and Technology, Issue 57/8, 2023, Page(s) 3085–3094, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.2c07497

ELIXIR and Toxicology: a community in development

Author(s): Marvin Martens; Rob Stierum; Emma L. Schymanski; Chris T. Evelo; Reza Aalizadeh; Hristo Aladjov; Kasia Arturi; Karine Audouze; Pavel Babica; Karel Berka; Jos Bessems; Ludek Blaha; Evan E Bolton; Montserrat Cases; Dimitrios Damalas; Kirtan Dave; Marco Dilger; Thomas Exner; Daan P. Geerke; Roland C. Grafström; Alasdair J. G. Gray; John M. Hancock; Henner Hollert; Nina Jeliazkova; Danyel Jennen; Fab
Published in: F1000Research 2021, Issue 10(ELIXIR):1129, 2021, Page(s) 1-20, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.74502.1

Tolerance of high temperature and associated effects on reproduction in euedaphic Collembola

Author(s): Liyan Xie, Stine Slotsbo, Martin Holmstrup
Published in: Journal of Thermal Biology, Issue Volume 113, 2023, Page(s) 103439, ISSN 0306-4565
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.jtherbio.2022.103439

AOP report: Chitin Synthase 1 Inhibition leading to Mortality in Arthropods

Author(s): Simon Schmid, You Song, Knut Erik Tollefsen
Published in: Environmental Toxicology and Chemistry, Issue 40, 2021, Page(s) 2112-2120, ISSN 0730-7268
Publisher: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5058

Effects of Life Stage on the Sensitivity of Folsomia candida to Four Pesticides

Author(s): Saúl Fernandes, Kees Buskermolen, Diana Ilyaskina, Ruben Bakker, Cornelis A. M. van Gestel
Published in: Environmental Toxicology and Chemistry, Issue Volume 00, Number 00, 2023, Page(s) 1-9, ISSN 2309-8031
Publisher: Wiley
DOI: 10.1002/etc.5682

The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry

Author(s): Taha, Hiba Mohammed; Aalizadeh, Reza; Alygizakis, Nikiforos; Antignac, Jean-Philippe; Arp, Hans Peter H.; Bade, Richard; Baker, Nancy; Belova, Lidia; Bijlsma, Lubertus; Bolton, Evan E.; Brack, Werner; Celma Tirado, Alberto; Chen, Wen-Ling; Cheng, Tiejun; Chirsir, Parviel; Cirka, L'ubos; D'Agostino, Lisa A.; Feunang, Yannick Djoumbou; Dulio, Valeria; Fischer, Stellan; Gago-Ferrero, Pablo; Galani, A
Published in: Environmental Sciences Europe, Issue Volume 34, 2022, Page(s) 104, ISSN 2190-4715
Publisher: SpringerOpen
DOI: 10.1186/s12302-022-00680-6

Chronic Effects of an Insect Growth Regulator (teflubenzuron) on the Life Cycle and Population Growth Rate of Folsomia candida

Author(s): Liyan Xie, Stine Slotsbo, Diana Ilyaskina, Valery Forbes, Martin Holmstrup
Published in: Environmental Toxicology and Chemistry, Issue 43/5, 2024, Page(s) 1173-1183, ISSN 0730-7268
Publisher: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5850

Flame Retardants-Mediated Interferon Signaling in the Pathogenesis of Nonalcoholic Fatty Liver Disease

Author(s): Chander K. Negi, Sabbir Khan, Hubert Dirven, Lola Bajard, Luděk Bláha
Published in: International Journal of Molecular Sciences, Issue 22/8, 2021, Page(s) 1-29, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084282

Exploring the Relationship Among Lipid Profile Changes, Growth, and Reproduction in Folsomia candida Exposed to Teflubenzuron Over Time

Author(s): Diana Ilyaskina, Saúl Fernandes,Matty P. Berg, Marja H. Lamoree, Cornelis A. M. van Gestel, Pim E. G. Leonards
Published in: Environmental Toxicology and Chemistry, Issue 43/5, 2024, Page(s) 1149-1160, ISSN 1552-8618
Publisher: Wiley
DOI: 10.1002/etc.5851

Other (1)

Chitin synthase 1 inhibition leading to mortality

Author(s): Simon Schmid, You Song, Knut Erik Tollefsen
Published in: OECD Series on Adverse Outcome Pathways, Issue 27, 2022
Publisher: OECD Publishing
DOI: 10.1787/35cd5862-en