Best chemical risk assessment professionals for maximum Ecosystem Services benefit

Informazioni relative al progetto

PRORISK

ID dell’accordo di sovvenzione: 859891

DOI

10.3030/859891

Progetto chiuso

Data della firma CE 27 Marzo 2020

Data di avvio 1 Aprile 2020

Data di completamento 31 Marzo 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 024 982,52

Contributo UE

€ 4 024 982,52

Coordinato da

Masarykova univerzita
Czechia

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (24)

Outreach activities report 2

Outreach activities report

Tools for evaluating chemical effects on interactions between multiple ecosystem functions driving ecosystem service delivery
Tools for assessing ecosystem service delivery effects at different temporal and spatial scales
Integration of multiple stressor impacts and translation of AOPs to population level
Scientific Newsletter 4

Scientific Newsletter

Outreach activities report 1

Outreach activities report

Guidance document on chemical analysis of selected contaminants
Conceptual AOPs proposed and submitted to AOP-Wiki

Conceptual AOPs proposed and submitted to AOPWiki

Status report on results from experimental and modelling studies on population-level outcomes

Status report on results from experimental and modelling studies on populationlevel outcomes

Paper on linkage of chemical-biological interaction and molecular initiating event

Paper on linkage of chemicalbiological interaction and molecular initiating event

Article in CORDIS magazine
Review on integration of AOP approaches in risk assessment of chemicals at individual and population levels
Tools/protocols for characterization of relevant MIE, KEs and AOs

Toolsprotocols for characterization of relevant MIE KEs and AOs

Tools for assessing chemical impact on service providing units and ecosystem functions providing ecosystem services
Current ecotoxicological methods for assessing risk of chemicals and other stressors for ecosystem service delivery
Scientific Newsletter 3

Scientific Newsletter

Scientific Newsletter 1

Scientific Newsletter

Scientific Newsletter 2

Scientific Newsletter

Developed qAOPs and refined AOPs submitted to OECD-EAMST expert evaluation
Outreach activities report 3

Outreach activities report

Review paper on toxicokinetics and biotransformation of selected contaminants including employment of imaging techniques
Paper on effects of natural stressors on toxicokinetics of selected model chemicals in PRORISK test organisms
Guidance for combining socio-economic, ecosystem services, and risk assessment information to inform risk management
Tools for facilitating translation of conventional ecotoxicological measurement to ecosystem service-relevant assessment endpoints

Websites, patent fillings, videos etc. (1)

Project website: project website (intra and internet) up and running

Other (1)

Workshop with stakeholders to promote implementation of PRORISK developed tools

Pubblicazioni

Peer reviewed articles (23)

Endocrine disrupting potential of replacement flame retardants-Review of current knowledge for nuclear receptors associated with reproductive outcomes

Autori: Lola Bajard, Chander K. Negi, Vicente Mustieles, Lisa Melymuk, Stéphane Jomini, Johanna Barthelemy-Berneron, Mariana F. Fernandez, Ludek Blaha
Pubblicato in: Environment International, Numero 153, 2021, Pagina/e 1-12, ISSN 0160-4120
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106550

Age and Synchronization of Daphnia magna Affect Sensitivityto Teflubenzuron in Acute Standardized Toxicity Tests

Autori: Simon Schmid, Jan T. Rundberget, You Song, Knut Erik Tollefsen
Pubblicato in: Environmental Toxicology and Chemistry, Numero 42/8, 2023, Pagina/e 1806-1815, ISSN 0730-7268
Editore: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5688

To Split or Not to Split: Characterizing Chemical Pollution Impacts in Aquatic Ecosystems with Species Sensitivity Distributions for Specific Taxonomic Groups

Autori: Susan A. Oginah, Leo Posthuma, Jaap Slootweg, Michael Hauschild, Peter Fantke
Pubblicato in: Environmental Science & Technology, Numero 57/39, 2023, Pagina/e 14526-14538, ISSN 1520-5851
Editore: American Chemical Society
DOI: 10.1021/acs.est.3c04968

Soil dwelling springtails are resilient to extreme drought in soil, but their reproduction is highly sensitive to small decreases in soil water potential

Autori: Yang Wang, Stine Slotsbo and Martin Holmstrup
Pubblicato in: Geoderma, Numero Volume 421, 2022, Pagina/e 115913, ISSN 0016-7061
Editore: Elsevier BV
DOI: 10.1016/j.geoderma.2022.115913

Replacement Flame-Retardant 2-Ethylhexyldiphenyl Phosphate (EHDPP) Disrupts Hepatic Lipidome: Evidence from Human 3D Hepatospheroid Cell Culture

Autori: Chander K. Negi; Darshak Gadara; Jiri Kohoutek; Lola Bajard; Zdeněk Spáčil; Ludek Blaha
Pubblicato in: Environmental Science and Technology, Numero 57, 2023, Pagina/e 2006-2018, ISSN 1520-5851
Editore: ACS PUBLICATIONS
DOI: 10.1021/acs.est.2c03998

An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis

Autori: Chander K. Negi, Lola Bajard, Jiri Kohoutek, Ludek Blaha
Pubblicato in: Environmental Pollution, Numero 289, 2021, Pagina/e 1-11, ISSN 0269-7491
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2021.117855

Toward harmonizing global pesticide regulations for surface freshwaters in support of protecting human health

Autori: Zijian Li, Peter Fantke
Pubblicato in: Journal of Environmental Management, Numero 301, 2022, Pagina/e 113909, ISSN 0301-4797
Editore: Academic Press
DOI: 10.1016/j.jenvman.2021.113909

Battery of In Vitro Bioassays: A Case Study for the Cost-Effective and Effect-Based Evaluation of Wastewater Effluent Quality

Autori: Nikiforos Alygizakis, Kelsey Ng, Niki Maragou, Sylvana Alirai, Peter Behnisch, Harrie Besselink, Peter Oswald, Lubos Cirka, Nikolaos S. Thomaidis, Jaroslav Slobodnik
Pubblicato in: Water, Numero Volume 19, 2023, Pagina/e 619, ISSN 2073-4441
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/w15040619

A trait-based approach to determine the risks of Zn to the overall health status of native fish species Barbus meridionalis

Autori: Amina Khalid, Cristina Galobart, Francesc Rubio-Gracia, Guluzar Atli, Helena Guasch, Anna Vila-Gispert
Pubblicato in: Aquatic Toxicology, Numero 262, 2023, Pagina/e 106661, ISSN 0166-445X
Editore: Elsevier BV
DOI: 10.1016/j.aquatox.2023.106661

Low soil Moisture Slows Uptake and Elimination Rates of Phenanthrene in Springtails

Autori: Yang Wang, Stine Slotsbo, Peter B Sørensen, Martin Holmstrup
Pubblicato in: Bulletin of Environmental Contamination and Toxicology, Numero 112/25, 2024, ISSN 0007-4861
Editore: Springer Verlag
DOI: 10.1007/s00128-024-03854-5

Increased daily temperature fluctuations exacerbate the toxicity of phenanthrene in Enchytraeus albidus (Enchytraeidae)

Autori: Wencai Dai, Stine Slotsbo, Liyan Xie, Yang Wang, Christian Damgaard, Martin Holmstrup
Pubblicato in: Science of The Total Environment, Numero 873, 2023, Pagina/e 162403, ISSN 0048-9697
Editore: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162403

Wide-Scope Target and Suspect Screening of Antibiotics in Effluent Wastewater from Wastewater Treatment Plants in Europe

Autori: Kelsey Ng ,Nikiforos A. Alygizakis, Nikolaos S. Thomaidis, Jaroslav Slobodnik
Pubblicato in: Antibiotics, Numero 12, 2023, Pagina/e 100, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics12010100

Antiandrogenic activity of novel flame retardants inmixtures: newly identified contribution from tris(2,3-dibromopropyl) isocyanurate (TDBP-TAZTO).

Autori: Lola Bajard, Hana Vespalcová, Chander K. Negi, Jiří Kohoutek, Luděk Bláha, Iva Sovadinová
Pubblicato in: Chemosphere, Numero volume 341, 2023, Pagina/e 1-11, ISSN 0045-6535
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.140004

Linking freshwater ecotoxicity to damage on ecosystem services in life cycle assessment

Autori: Susan A. Oginah , Leo Posthuma, Lorraine Maltby, Michael Hauschild Peter Fantke
Pubblicato in: Environment International, Numero Volume 171, 2023, Pagina/e 107705, ISSN 0160-4120
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107705

Influence of Soil Moisture on Bioaccumulation, Growth, and Recruitment of Folsomia candida Exposed to Phenanthrene-Polluted Soil

Autori: Yang Wang, Stine Slotsbo, Christian Frølund Damgaard, and Martin Holmstrup
Pubblicato in: Environmental Science and Technology, Numero 57/8, 2023, Pagina/e 3085–3094, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.2c07497

ELIXIR and Toxicology: a community in development

Autori: Marvin Martens; Rob Stierum; Emma L. Schymanski; Chris T. Evelo; Reza Aalizadeh; Hristo Aladjov; Kasia Arturi; Karine Audouze; Pavel Babica; Karel Berka; Jos Bessems; Ludek Blaha; Evan E Bolton; Montserrat Cases; Dimitrios Damalas; Kirtan Dave; Marco Dilger; Thomas Exner; Daan P. Geerke; Roland C. Grafström; Alasdair J. G. Gray; John M. Hancock; Henner Hollert; Nina Jeliazkova; Danyel Jennen; Fab
Pubblicato in: F1000Research 2021, Numero 10(ELIXIR):1129, 2021, Pagina/e 1-20, ISSN 2046-1402
Editore: F1000 Research Ltd.
DOI: 10.12688/f1000research.74502.1

Tolerance of high temperature and associated effects on reproduction in euedaphic Collembola

Autori: Liyan Xie, Stine Slotsbo, Martin Holmstrup
Pubblicato in: Journal of Thermal Biology, Numero Volume 113, 2023, Pagina/e 103439, ISSN 0306-4565
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.jtherbio.2022.103439

AOP report: Chitin Synthase 1 Inhibition leading to Mortality in Arthropods

Autori: Simon Schmid, You Song, Knut Erik Tollefsen
Pubblicato in: Environmental Toxicology and Chemistry, Numero 40, 2021, Pagina/e 2112-2120, ISSN 0730-7268
Editore: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5058

Effects of Life Stage on the Sensitivity of Folsomia candida to Four Pesticides

Autori: Saúl Fernandes, Kees Buskermolen, Diana Ilyaskina, Ruben Bakker, Cornelis A. M. van Gestel
Pubblicato in: Environmental Toxicology and Chemistry, Numero Volume 00, Number 00, 2023, Pagina/e 1-9, ISSN 2309-8031
Editore: Wiley
DOI: 10.1002/etc.5682

The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry

Autori: Taha, Hiba Mohammed; Aalizadeh, Reza; Alygizakis, Nikiforos; Antignac, Jean-Philippe; Arp, Hans Peter H.; Bade, Richard; Baker, Nancy; Belova, Lidia; Bijlsma, Lubertus; Bolton, Evan E.; Brack, Werner; Celma Tirado, Alberto; Chen, Wen-Ling; Cheng, Tiejun; Chirsir, Parviel; Cirka, L'ubos; D'Agostino, Lisa A.; Feunang, Yannick Djoumbou; Dulio, Valeria; Fischer, Stellan; Gago-Ferrero, Pablo; Galani, A
Pubblicato in: Environmental Sciences Europe, Numero Volume 34, 2022, Pagina/e 104, ISSN 2190-4715
Editore: SpringerOpen
DOI: 10.1186/s12302-022-00680-6

Chronic Effects of an Insect Growth Regulator (teflubenzuron) on the Life Cycle and Population Growth Rate of Folsomia candida

Autori: Liyan Xie, Stine Slotsbo, Diana Ilyaskina, Valery Forbes, Martin Holmstrup
Pubblicato in: Environmental Toxicology and Chemistry, Numero 43/5, 2024, Pagina/e 1173-1183, ISSN 0730-7268
Editore: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5850

Flame Retardants-Mediated Interferon Signaling in the Pathogenesis of Nonalcoholic Fatty Liver Disease

Autori: Chander K. Negi, Sabbir Khan, Hubert Dirven, Lola Bajard, Luděk Bláha
Pubblicato in: International Journal of Molecular Sciences, Numero 22/8, 2021, Pagina/e 1-29, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084282

Exploring the Relationship Among Lipid Profile Changes, Growth, and Reproduction in Folsomia candida Exposed to Teflubenzuron Over Time

Autori: Diana Ilyaskina, Saúl Fernandes,Matty P. Berg, Marja H. Lamoree, Cornelis A. M. van Gestel, Pim E. G. Leonards
Pubblicato in: Environmental Toxicology and Chemistry, Numero 43/5, 2024, Pagina/e 1149-1160, ISSN 1552-8618
Editore: Wiley
DOI: 10.1002/etc.5851

Other (1)

Chitin synthase 1 inhibition leading to mortality

Autori: Simon Schmid, You Song, Knut Erik Tollefsen
Pubblicato in: OECD Series on Adverse Outcome Pathways, Numero 27, 2022
Editore: OECD Publishing
DOI: 10.1787/35cd5862-en