Deliverables Websites, patent fillings, videos etc. (1) CORVOS homepage (D6.4) Established homepage with constant announcements Documents, reports (2) Press releases and interviews (D6.3) Press releases interviews and overview articles in local newspapers and new social media also M10M22M35M46 Presentation at Complement congress (D6.9) Poster or Oral presentation at C congress also M34 Publications Peer reviewed articles (19) Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs. Author(s): Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Sinkovits G, Cervenak L, Würzner R, Prohászka Z Published in: Frontiers in Immunology, 2022, ISSN 1664-3224 Publisher: Frontiers Media S.A. DOI: 10.3389/fimmu.2022.1039765 Colistin resistance mutations in phoQ can sensitize Klebsiella pneumoniae to IgM-mediated complement killing Author(s): van der Lans SPA, Janet-Maitre M, Masson FM, Walker KA, Doorduijn DJ, Janssen AB, van Schaik W, Attrée I, Rooijakkers SHM, Bardoel BW Published in: Scientific Report, 2023, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-023-39613-5 Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children Author(s): Sinkovits G, Schnur J, Hurler L, Kiszel P, Prohászka ZZ, Sík P, Kajdácsi E, Cervenak L, Maráczi V, Dávid M, Zsigmond B, Rimanóczy É, Bereczki C, Willems L, Toonen EJM, Prohászka Z Published in: Scientific Reports, 2022, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-022-23806-5 Systemic Inflammation and Complement Activation Parameters Predict Clinical Outcome of Severe SARS-CoV-2 Infections Author(s): Silke Huber - Mariam Massri - Marco Grasse -Verena Fleischer - Sára Kellnerová - Verena Harpf - Ludwig Knabl - Ludwig Knabl, Sr. - Tatjana Heiner - Moritz Kummann - Magdalena Neurauter - Günter Rambach - Cornelia Speth - Reinhard Würzner Published in: Viruses, 2021, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13122376 Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups Author(s): Hurler L, Szilágyi Á, Mescia F, Bergamaschi L, Mező B, Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Würzner R; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITII Published in: Frontiers in Immunology, 2023, ISSN 1664-3224 Publisher: Frontiers Media S.A. DOI: 10.3389/fimmu.2023.1162171 Clinical Isolates of Acinetobacter spp. Are Highly Serum Resistant Despite Efficient Recognition by the Complement System Author(s): Magda M, Bettoni S, Laabei M, Fairley D, Russo TA, Riesbeck K, Blom AM Published in: Frontiers in Immunology, Issue 16643224, 2022, ISSN 1664-3224 Publisher: Frontiers Media SA DOI: 10.3389/fimmu.2022.814193 Differentiating Between Activation via the Lectin or the Classical Complement Pathway in Patients with Systemic Lupus Erythematosus Author(s): Larsen ML, Troldborg A, Toonen EJM, Hurler L, Prohaszka Z, Cervenak L, Hansen AG, Thiel S Published in: Clinical and Experimental Immunology, 2023, ISSN 1365-2249 Publisher: Oxford University Press DOI: 10.1093/cei/uxad070 Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release Author(s): de Boer E, Sokolova M, Quach HQ, McAdam KE, Götz MP, Chaban V, Vaage J, Fageräng B, Woodruff TM, Garred P, Nilsson PH, Mollnes TE, Pischke SE Published in: Journal of Immunology, Issue 00221767, 2022, ISSN 0022-1767 Publisher: American Association of Immunologists DOI: 10.4049/jimmunol.2101191 Genome-wide screen in human plasma identifies multifaceted complement evasion of Pseudomonas aeruginosa Author(s): Manon Janet-Maitre 1, Stéphane Pont 1, Frerich M Masson 2, Serena Sleiman 1, Julian Trouillon 1, Mylène Robert-Genthon 1, Benoît Gallet 3, Chantal Dumestre-Perard 4 5, Sylvie Elsen 1, Christine Moriscot 3, Bart W Bardoel 2, Suzan H M Rooijakkers 2, François Cretin 1, Ina Attrée 1 Published in: Plos Pathogens, 2023, ISSN 1553-7366 Publisher: Public Library of Science DOI: 10.1371/journal.ppat.1011023 Associations between the von Willebrand Factor-ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality Author(s): Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Mező B, Csuka D, Hurler L, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Prohászka Z Published in: Thrombosis and Haemostasis, Issue 03406245, 2022, ISSN 0340-6245 Publisher: Schattauer DOI: 10.1055/s-0041-1740182 Complement Genetic Variants and FH Desialylation in S. pneumoniae-Haemolytic Uraemic Syndrome. Author(s): Irene Gómez Delgado; Fernando Corvillo; Fernando Corvillo; Pilar Nozal; Pilar Nozal; Emilia Arjona; Emilia Arjona; Álvaro Madrid; Marta Melgosa; Juan Bravo; Ágnes Szilágyi; Dorottya Csuka; Nóra Veszeli; Zoltán Prohászka; Pilar Sánchez-Corral; Pilar Sánchez-Corral Published in: Frontiers in Immunology, 2021, ISSN 1664-3224 Publisher: Frontiers Media S.A. DOI: 10.3389/fimmu.2021.641656 Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus – When Incubated in Human Whole Blood Author(s): Medeiros, Pedro Miguel Coelho - Schjalm, Camilla - Christiansen, Dorte - Sokolova, Marina - Pischke, Soeren Erik - Würzner, Reinhard - Mollnes, Tom Eirik - Barratt-Due, Andreas Published in: Shock, 2021, ISSN 1540-0514 Publisher: Lippincott Williams & Wilkins DOI: 10.1097/shk.0000000000001834 HIV-1 Trans Infection via TNTs Is Impeded by Targeting C5aR Author(s): Bertacchi G, Posch W, Wilflingseder D Published in: Biomolecules, Issue 2218273X, 2022, ISSN 2218-273X Publisher: MDPI DOI: 10.3390/biom12020313 Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection Author(s): György Sinkovits - Blanka Mező - Marienn Réti - Veronika Müller - Zsolt Iványi - János Gál - László Gopcsa - Péter Reményi - Beáta Szathmáry - Botond Lakatos - János Szlávik - Ilona Bobek - Zita Z Prohászka - Zsolt Förhécz - Dorottya Csuka - Lisa Hurler - Erika Kajdácsi - László Cervenak - Petra Kiszel - Tamás Masszi - István Vályi-Nagy - Zoltán Prohászka Published in: Frontiers in Immunology, 2021, ISSN 1664-3224 Publisher: Frontiers Media SA DOI: 10.3389/fimmu.2021.663187 Hijacking the human complement inhibitor C4b-binding protein by the sporozoite stage of the Plasmodium falciparum parasite Author(s): Khattab A, Rezola M, Barroso M, Kyrklund M, Pihlajamaa T, Freitag TL, van Gemert G-J, Bousema T, Permi P, Turunen O, Sauerwein R, Luty AJF and Meri S Published in: Frontiers in Immunology, 2022, ISSN 1664-3224 Publisher: Frontiers Media S.A. DOI: 10.3389/fimmu.2022.1051161 C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2-infected primary human airway epithelia Author(s): Posch W, Vosper J, Noureen A, Zaderer V, Witting C, Bertacchi G, Gstir R, Filipek PA, Bonn GK, Huber LA, Bellmann-Weiler R, Lass-Flörl C, Wilflingseder D Published in: Journal of Allergy and Clinical Immunology, Issue 00916749, 2021, ISSN 0091-6749 Publisher: Mosby Inc. DOI: 10.1016/j.jaci.2021.03.038 Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19 Author(s): Götz MP, Skjoedt MO, Bayarri-Olmos R, Hansen CB, Pérez-Alós L, Jarlhelt I, Benfield T, Rosbjerg A, Garred P Published in: Journal of Innate Immunity, Issue 16628128, 2022, ISSN 1662-8128 Publisher: Karger DOI: 10.1159/000525508 Comprehensive Update and Revision of Nomenclature on Complement C6 and C7 Variants Author(s): Massri M, Foco L, Würzner R Published in: Journal of Immunology, Issue 00221767, 2022, ISSN 0022-1767 Publisher: American Association of Immunologists DOI: 10.4049/jimmunol.2200045 Complement Levels at Admission Reflecting Progression to Severe Acute Kidney Injury (AKI) in Coronavirus Disease 2019 (COVID-19): A Multicenter Prospective Cohort Study Author(s): Henry BM, Sinkovits G, Szergyuk I, de Oliveira MHS, Lippi G, Benoit JL, Favaloro EJ, Pode-Shakked N, Benoit SW, Cooper DS, Müller V, Iványi Z, Gál J, Réti M, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Hurler L, Kajdácsi E, Cervenak L, Mező B, Kiszel P, Masszi T, Vályi-Nagy I, Prohászka Z Published in: Frontiers in Medicine, Issue 2296858X, 2022, ISSN 2296-858X Publisher: Frontiers Media SA DOI: 10.3389/fmed.2022.796109 Searching for OpenAIRE data... 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