anti-Bacterial Innovative Vaccine Training Network.

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Social media campaign & Podcast BactiVax Web-site

Social media campaign Podcast BactiVax Website The campaign will run throughout the project from M4 to M48 The podcasts will be due on M20 and M47

Patent application: Protective antibodies against P. aeruginosa

Patent applications will be filed on successful protective therapeutic antibodies against P. aeruginosa by month 38.

Patents applications on TLR directed adjuvants

Patent applications on TLR4-directed or other TLR-directed adjuvants (M38)

BactiVax LinkedIn group

BactiVax LinkedIn Group established and all members of the consortium following the group LMU will lead this and will be supported by CNRIBB

Patent application: Effective bicyclic peptide vaccine

EPFL will file patents on the most effective bicyclic peptide vaccines

Protocols: novel NMR methods to explore molecu-lar recognition processes to target

Protocols novel NMR methods to explore molecular recognition processes to target mechanism of action of TLR agonists There will be two drafts of the protocols at month 24 and 36

Publications submitted on effective vaccine antigens

Publications submitted on effective vaccine antigens (M40, M46). UCD, QUB, LMU and Lio will submit papers on their own antigens with co-authors from the consortium as appropriate

Publication submitted: Immune responses to vaccine formulations

Publication: Innate and acquired (T-cell and B cell) responses to adjuvanted vaccine formulations. It is antcipated that Imperial and CIC-BioGune will be co-authors on this publication with other authors as relevant.

Report on Vaccine advocacy activities

Reports on Vaccine advocacy activities will be prepared annually at 9 21 33 and 45 months

Communication and Public engagement Plan

Communication and Public Engagement strategy developed and circulated to BactiVax network

Publication submitted on the effect of novel pep-tide-based therapeutic vaccine candidates

Publication submitted on the effect of novel peptide-based therapeutic vaccine candidates will be co-authored by SGUL and ELTE with additional authors from the consortium as appropriate.

Publication submitted: Effective vaccine antigen and adjuvant combinations

Publication: Effective prophylactic and/or therapeutic vaccine-adjuvant combinations against P. aeruginosa and Burkholderia

Potential inputs for policy feedback

We will review the overall outputs from the BactiVax project and will collate relevant outputs that may inform Vaccine policymakers within the Commission and in relevant stakeholders such as WHO and GAVI

Publication on the preparation of multi-epitope peptide conjugates ( formulation of peptide-drug conjugates and adjuvant

Publication on the preparation of multi-epitope peptide conjugates which will describe the formulation of peptide-drug conjugates and adjuvant will be submitted by month 40

Consortium quarterly newsletter (every 4 months)

Consortium quarterly newsletter will be prepared and circulated across the consortium every quarter. It will also be posted on the BactiVax website for maximal public dissemination.

Plan for the Exploitation and Dissemination of results (PEDR) plan

Plan for the Exploitation and Dissemination of results PEDR in place

Publications

The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes

Auteurs: Keren Turton, Hannah J. Parks, Paulina Zarodkiewicz, Mohamad A. Hamad, Rachel Dwane, Georgiana Parau, Rebecca J. Ingram, Rebecca C. Coll, Clare E. Bryant, Miguel A. Valvano
Publié dans: Cell Reports, Numéro 42, 2024, Page(s) 113012, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2023.113012

Immunogenicity of PE18, PE31, and PPE26 proteins from Mycobacterium tuberculosis in humans and mice

Auteurs: María García-Bengoa, Emil Joseph Vergara, Andy C. Tran, Lorenzo Bossi, Andrea M. Cooper, John E. Pearl, Tufária Mussá, Maren von Köckritz-Blickwede, Mahavir Singh, Rajko Reljic
Publié dans: Frontiers in Immunology, Numéro 14, 2023, ISSN 1664-3224
Éditeur: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1307429

Structural Basis of PE_PGRS Polymorphism, a Tool for Functional Modulation

Auteurs: Eliza Kramarska, Flavio De Maio, Giovanni Delogu, Rita Berisio
Publié dans: Biomolecules, Numéro 13, 2023, Page(s) 812, ISSN 2218-273X
Éditeur: MDPI
DOI: 10.3390/biom13050812

Mammalian Neuropeptides as Modulators of Microbial Infections: Their Dual Role in Defense versus Virulence and Pathogenesis

Auteurs: Daria Augustyniak, Eliza Kramarska, Paweł Mackiewicz, Magdalena Orczyk-Pawiłowicz, Fionnuala T. Lundy
Publié dans: International Journal of Molecular Sciences, Numéro 22(7), 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22073658

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells

Auteurs: Flavio De Maio, Alessandro Salustri, Basem Battah, Ivana Palucci, Federica Marchionni, Silvia Bellesi, Valentina Palmieri, Massimiliano Papi, Eliza Kramarska, Maurizio Sanguinetti, Michela Sali, Rita Berisio, and Giovanni Delogu.
Publié dans: Virulence, Numéro Volume 13, Numéro 1, 2022, Page(s) 868-884, ISSN 2150-5608
Éditeur: Taylor & Francis
DOI: 10.1080/21505594.2021.1897247

A Global Picture of Molecular Changes Associated to LPS Treatment in THP-1 Derived Human Macrophages by Fourier Transform Infrared Microspectroscopy

Auteurs: Diletta Ami, Ana Rita Franco, Valentina Artusa, Paolo Mereghetti, Francesco Peri, Antonino Natalello
Publié dans: International Journal of Molecular Sciences, Numéro 23, 2024, Page(s) 13447, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232113447

An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria

Auteurs: Marwa Naguib, Nicolás Feldman, Paulina Zarodkiewicz, Holly Shropshire, Christina Biamis, Omar M. El-Halfawy, Julia McCain, Clément Dezanet, Jean-Luc Décout, Yin Chen, Gonzalo Cosa, Miguel A. Valvano
Publié dans: PLOS Biology, Numéro 20, 2022, Page(s) e3001610, ISSN 1545-7885
Éditeur: PLOS
DOI: 10.1371/journal.pbio.3001610

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

Auteurs: Andrew O'Connor, Irene Jurado‐Martín, Margaritha M. Mysior, Anotidaishe L. Manzira, Joanna Drabinska, Jeremy C. Simpson, Mary Lucey, Kirsten Schaffer, Rita Berisio, Siobhán McClean
Publié dans: MicrobiologyOpen, Numéro 12, 2023, ISSN 2045-8827
Éditeur: John Wiley and Sons Inc.
DOI: 10.1002/mbo3.1311

BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis

Auteurs: Julen Tomás-Cortázar, Lorenzo Bossi, Conor Quinn, Catherine J. Reynolds, David K. Butler, Niamh Corcoran, Maitiú Ó Murchú, Eve McMahon, Mahavir Singh, Patpong Rongkard, Juan Anguita, Alfonso Blanco, Susanna J. Dunachie, Daniel Altmann, Rosemary J. Boyton, Johan Arnold, Severine Giltaire, Siobhán McClean
Publié dans: Frontiers in Immunology, Numéro 12, 2021, ISSN 1664-3224
Éditeur: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.767359

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Auteurs: Bognar, Zsolt ; Mothukuri, Ganesh K. ; Nielsen, Alexander L. ; Merz, Manuel L. ; Panzar, Peter M. F. ; Heinis, Christian
Publié dans: Organic & Biomolecular Chemistry, 2022, Page(s) 5699-5703, ISSN 1477-0520
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2ob00910b

A Structural View at Vaccine Development against M. tuberculosis

Auteurs: Maria Romano, Flavia Squeglia, Eliza Kramarska, Giovanni Barra, Han-Gyu Choi, Hwa-Jung Kim, Alessia Ruggiero, Rita Berisio
Publié dans: Cells, Numéro 12, 2023, Page(s) 317, ISSN 2073-4409
Éditeur: Cells
DOI: 10.3390/cells12020317

Marked enhancement of the immunogenicity of plant‐expressed <scp>IgG‐Fc</scp> fusion proteins by inclusion of cholera toxin non‐toxic B subunit within the single polypeptide

Auteurs: Mi‐Young Kim, Emil Vergara, Andy Tran, Matthew John Paul, Tae‐Ho Kwon, Julian K.C. Ma, Yong‐Suk Jang, Rajko Reljic
Publié dans: Plant Biotechnology Journal, Numéro 22, 2024, Page(s) 1402-1416, ISSN 1467-7644
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/pbi.14275

Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development

Auteurs: Samuel T Pasco and Juan Anguita
Publié dans: Cells, Numéro 9, 2020, Page(s) E2109, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9092109

Exploring multivalent carbohydrate–protein interactions by NMR

Auteurs: Jon I. Quintana, Unai Atxabal, Luca Unione, Ana Ardá, Jesús Jiménez-Barbero
Publié dans: Chemical Society Reviews, Numéro 52, 2024, Page(s) 1591-1613, ISSN 0306-0012
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2cs00983h

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

Auteurs: Sevan Habeshian, Manuel Leonardo Merz, Gontran Sangouard, Ganesh Kumar Mothukuri, Mischa Schüttel, Zsolt Bognár, Cristina Díaz-Perlas, Jonathan Vesin, Julien Bortoli Chapalay, Gerardo Turcatti, Laura Cendron, Alessandro Angelini, Christian Heinis
Publié dans: Nature Communications, Numéro 13, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-31428-8

Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection

Auteurs: Chiara Bellini, Emil Vergara, Fruzsina Bencs, Kinga Fodor, Szilvia Bősze, Denis Krivić, Bernadett Bacsa, Sára Eszter Surguta, József Tóvári, Rajko Reljic, Kata Horváti
Publié dans: Bioconjugate Chemistry, Numéro 34, 2023, Page(s) 1738-1753, ISSN 1043-1802
Éditeur: American Chemical Society
DOI: 10.1021/acs.bioconjchem.3c00273

Current Status on Therapeutic Molecules Targeting Siglec Receptors

Auteurs: María Pia Lenza, Unai Atxabal, Iker Oyenarte, Jesús Jiménez-Barbero, June Ereño-Orbea
Publié dans: Cells, Numéro 9/12, 2020, Page(s) 2691, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9122691

Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

Auteurs: Alexander L. Nielsen, Zsolt Bognar, Ganesh K. Mothukuri, Anne Zarda, Mischa Schüttel, Manuel L. Merz, Xinjian Ji, Edward J. Will, Monica Chinellato, Christian R. O. Bartling, Kristian Strømgaard, Laura Cendron, Alessandro Angelini, Christian Heinis
Publié dans: Angewandte Chemie Int. Ed., Numéro Volume 63, Numéro 26, 2024, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400350

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants

Auteurs: Alessio Romerio, Nicole Gotri, Ana Rita Franco, Valentina Artusa, Mohammed Monsoor Shaik, Samuel T. Pasco, Unai Atxabal, Alejandra Matamoros-Recio, Marina Mínguez-Toral, Juan Diego Zalamea, Antonio Franconetti, Nicola G. A. Abrescia, Jesus Jimenez-Barbero, Juan Anguita, Sonsoles Martín-Santamaría, Francesco Peri
Publié dans: Journal of Medicinal Chemistry, Numéro 66, 2023, Page(s) 3010-3029, ISSN 0022-2623
Éditeur: American Chemical Society
DOI: 10.1021/acs.jmedchem.2c01998

Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists

Auteurs: Diletta Ami, Ana Rita Franco, Valentina Artusa, Alessio Romerio, Mohammed Monsoor Shaik, Alice Italia, Juan Anguita, Samuel Pasco, Paolo Mereghetti, Francesco Peri, Antonino Natalello
Publié dans: Talanta, Numéro 275, 2024, Page(s) 126104, ISSN 0039-9140
Éditeur: Elsevier BV
DOI: 10.1016/j.talanta.2024.126104

Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling

Auteurs: Unai Atxabal, Corwin Nycholat, Johannes M. Pröpster, Andrea Fernández, Iker Oyenarte, Maria Pia Lenza, Antonio Franconetti, Cátia O. Soares, Helena Coelho, Filipa Marcelo, Mario Schubert, James C. Paulson, Jesús Jiménez-Barbero, June Ereño-Orbea
Publié dans: ACS Chemical Biology, Numéro 19, 2024, Page(s) 483-496, ISSN 1554-8929
Éditeur: American Chemical Society
DOI: 10.1021/acschembio.3c00664

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

Auteurs: Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, Klaudia Sobczak, Felix Elortza, James D. Sutherland, Rosa Barrio, Filipa Marcelo, Jesús Jiménez-Barbero, Asis Palazon, June Ereño-Orbea
Publié dans: Nature Communications, Numéro 14, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-39119-8

Recent Advances in the Development of Protein- and Peptide-Based Subunit Vaccines against Tuberculosis

Auteurs: Chiara Bellini and Kata Horváti
Publié dans: Cells, Numéro 9/12, 2020, Page(s) 2673, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9122673

Current Advances in Burkholderia Vaccines Development

Auteurs: Guanbo Wang, Paulina Zarodkiewicz, Miguel A. Valvano
Publié dans: Cells, Numéro 9/12, 2020, Page(s) 2671, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9122671

Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae

Auteurs: Barbara Maciejewska, Flavia Squeglia, Agnieszka Latka, Mario Privitera, Sebastian Olejniczak, Paulina Switala, Alessia Ruggiero, Daniela Marasco, Eliza Kramarska, Zuzanna Drulis-Kawa, Rita Berisio
Publié dans: mBio, Numéro 14, 2024, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/mbio.01329-23

Overcoming Challenges in Chemical Glycosylation to Achieve Innovative Vaccine Adjuvants Possessing Enhanced TLR4 Activity

Auteurs: Alessio Romerio, Ana Rita Franco, Melanie Shadrick, Mohammed Monsoor Shaik, Valentina Artusa, Alice Italia, Federico Lami, Alexei V. Demchenko, Francesco Peri
Publié dans: ACS Omega, Numéro 8, 2023, Page(s) 36412-36417, ISSN 2470-1343
Éditeur: ACS Omega
DOI: 10.1021/acsomega.3c05363

A modified mycobacterial growth inhibition assay for the functional assessment of vaccine-mediated immunity

Auteurs: Emil Joseph Vergara, Andy Cano Tran, Matthew J. Paul, Thomas Harrison, Andrea Cooper, Rajko Reljic
Publié dans: npj Vaccines, Numéro 9, 2024, ISSN 2059-0105
Éditeur: Springer Nature
DOI: 10.1038/s41541-024-00906-z

Role of phagocyte extracellular traps during Mycobacterium tuberculosis infections and tuberculosis disease processes

Auteurs: María García-Bengoa, Marita Meurer, Ralph Goethe, Mahavir Singh, Rajko Reljic, Maren von Köckritz-Blickwede
Publié dans: Frontiers in Microbiology, Numéro 14, 2023, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2023.983299

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

Auteurs: Irene Jurado-Martín, Maite Sainz-Mejías, Siobhán McClean
Publié dans: International Journal of Molecular Sciences, Numéro 22/6, 2021, Page(s) 3128, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22063128

Implications of O-glycan modifications in the hinge region of a plant-produced SARS-CoV-2-IgA antibody on functionality

Auteurs: Pia Uetz, Kathrin Göritzer, Emil Vergara, Stanislav Melnik, Clemens Grünwald-Gruber, Rudolf Figl, Ala-Eddine Deghmane, Elisabetta Groppelli, Rajko Reljic, Julian K.-C. Ma, Eva Stöger, Richard Strasser
Publié dans: Frontiers in Bioengineering and Biotechnology, Numéro 12, 2024, ISSN 2296-4185
Éditeur: Frontiers in Bioengineering and Biotechnology
DOI: 10.3389/fbioe.2024.1329018

Quantifying Siglec-sialylated ligand interactions: a versatile 19F-T2 CPMG filtered competitive NMR displacement assay

Auteurs: Unai Atxabal, Andrea Fernández, Maria Jesús Moure, Klaudia Sobczak, Corwin Nycholat, Verónica Almeida-Marrero, Iker Oyenarte, James C. Paulson, Andrés de la Escosura, Tomás Torres, Niels C. Reichardt, Jesús Jiménez-Barbero, June Ereño-Orbea
Publié dans: Chemical Science, Numéro 15, 2024, Page(s) 10612-10624, ISSN 2041-6520
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d4sc01723d

Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps

Auteurs: María García-Bengoa, Marita Meurer, Matthias Stehr, Ayssar A. Elamin, Mahavir Singh, Wulf Oehlmann, Matthias Mörgelin, Maren von Köckritz-Blickwede
Publié dans: Frontiers in Immunology, Numéro 14, 2023, ISSN 1664-3224
Éditeur: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1206529

Predictive and Experimental Immunogenicity of Burkholderia Collagen-like Protein 8-Derived Antigens

Auteurs: Megan E. Grund, Eliza Kramarska, Soo Jeon Choi, Dudley H. McNitt, Christopher P. Klimko, Nathaniel O. Rill, Jennifer L. Dankmeyer, Jennifer L. Shoe, Melissa Hunter, David P. Fetterer, Zander M. Hedrick, Ivan Velez, Sergei S. Biryukov, Christopher K. Cote, Rita Berisio, Slawomir Lukomski
Publié dans: MDPI Vaccines, Numéro 9(11), 2021, Page(s) 1219, ISSN 2076-393X
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9111219

Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive ESKAPE pathogens

Auteurs: Océane Sadones, Eliza Kramarska, Diana Laverde, Rita Berisio, Johannes Huebner, Felipe Romero-Saavedra
Publié dans: BMC Microbiology, Numéro 24, 2024, ISSN 1471-2180
Éditeur: BioMed Central
DOI: 10.1186/s12866-024-03427-w

Mucosal and systemic immune responses after a single intranasal dose of nanoparticle and spore-based subunit vaccines in mice with pre-existing lung mycobacterial immunity

Auteurs: Emil Joseph Vergara, Andy Cano Tran, Mi-Young Kim, Tufária Mussá, Matthew J. Paul, Thomas Harrison, Rajko Reljic
Publié dans: Frontiers in Immunology, Numéro 14, 2023, ISSN 1664-3224
Éditeur: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1306449

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

Auteurs: Ainize Peña-Cearra, Ainhoa Palacios, Aize Pellon, Janire Castelo, Samuel Tanner Pasco, Iratxe Seoane, Diego Barriales, Jose Ezequiel Martin, Miguel Ángel Pascual-Itoiz, Monika Gonzalez-Lopez, Itziar Martín-Ruiz, Nuria Macías-Cámara, Naiara Gutiez, Sarai Araujo-Aris, Ana Mª Aransay, Héctor Rodríguez, Juan Anguita, Leticia Abecia
Publié dans: Communications Biology, Numéro 7, 2024, ISSN 2399-3642
Éditeur: Communications Biology
DOI: 10.1038/s42003-024-05867-6

Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies

Auteurs: Ana Rita Franco, Océane Sadones, Alessio Romerio, Valentina Artusa, Mohammed Monsoor Shaik, Samuel T. Pasco, Alice Italia, Simona D’Amato, Juan Anguita, Johannes Huebner, Felipe Romero-Saavedra, Francesco Peri
Publié dans: Journal of Medicinal Chemistry, Numéro 67, 2024, Page(s) 5603-5616, ISSN 0022-2623
Éditeur: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c02215

Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody

Auteurs: Maria Pia Lenza, Unai Atxabal, Corwin Nycholat, Iker Oyenarte, Antonio Franconetti, Jon Imanol Quintana, Sandra Delgado, Reyes Núñez-Franco, Carmen Teresa Garnica Marroquín, Helena Coelho, Luca Unione, Gonzalo Jiménez-Oses, Filipa Marcelo, Mario Schubert, James C. Paulson, Jesús Jiménez-Barbero, June Ereño-Orbea
Publié dans: JACS Au, Numéro 3, 2023, Page(s) 204-215, ISSN 2691-3704
Éditeur: American Chemical Society
DOI: 10.1021/jacsau.2c00592

Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

Auteurs: Naroa Goikoetxea‐Usandizaga, Marina Serrano‐Maciá, Teresa C. Delgado, Jorge Simón, David Fernández Ramos, Diego Barriales, Maria E. Cornide, Mónica Jiménez, Marina Pérez‐Redondo, Sofia Lachiondo‐Ortega, Rubén Rodríguez‐Agudo, Maider Bizkarguenaga, Juan Diego Zalamea, Samuel T. Pasco, Daniel Caballero‐Díaz, Benedetta Alfano, Miren Bravo, Irene González‐Recio, Maria Mercado
Publié dans: Hepatology, Numéro 75, 2024, Page(s) 550-566, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/hep.32149

Serological analysis reveals differential antibody responses between TB patients and latently infected individuals from the TB endemic country of Mozambique

Auteurs: Andy C. Tran, Eugenia Boariu, María García-Bengoa, Mi-Young Kim, Emil Joseph Vergara, Tufária Mussá, Rajko Reljic
Publié dans: Frontiers in Medicine, Numéro 10, 2023, ISSN 2296-858X
Éditeur: Frontiers in Medicine
DOI: 10.3389/fmed.2023.1286785

Understanding Pseudomonas aeruginosa–Host Interactions: The Ongoing Quest for an Efficacious Vaccine

Auteurs: Maite Sainz-Mejías, Irene Jurado-Martín, Siobhán McClean
Publié dans: Cells, Numéro 9/12, 2020, Page(s) 2617, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9122617

PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response

Auteurs: Eliza Kramarska, Flavia Squeglia, Flavio De Maio, Giovanni Delogu, Rita Berisio
Publié dans: Cells, Numéro 10/1, 2021, Page(s) 161, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10010161

Developing New Anti-Tuberculosis Vaccines: Focus on Adjuvants

Auteurs: Ana Rita Franco, Francesco Peri
Publié dans: Cells, Numéro 10/1, 2021, Page(s) 78, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10010078

Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking

Auteurs: Ana Rita Franco, Valentina Artusa, Francesco Peri
Publié dans: Methods in Molecular Biology, Toll-Like Receptors, 2023, Page(s) 57-74, ISBN 978-1-0716-3366-3
Éditeur: Springer US
DOI: 10.1007/978-1-0716-3366-3_3

Nuclear Magnetic Resonance Techniques for the Study of Glycan Interactions

Auteurs: Unai Atxabal, Ana Gimeno, Jesús Jiménez-Barbero
Publié dans: Comprehensive Glycoscience, 2024, Page(s) 329-345, ISBN 9780128222447
Éditeur: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00015-8

Droits de propriété intellectuelle

METHOD FOR PREPARING A LIBRARY OF PEPTIDES OR A PEPTIDE

Numéro de demande/publication: 20 22061138
Date: 2022-04-27
Demandeur(s): ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

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