anti-Bacterial Innovative Vaccine Training Network.

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Social media campaign & Podcast BactiVax Web-site

Social media campaign Podcast BactiVax Website The campaign will run throughout the project from M4 to M48 The podcasts will be due on M20 and M47

Patent application: Protective antibodies against P. aeruginosa

Patent applications will be filed on successful protective therapeutic antibodies against P. aeruginosa by month 38.

Patents applications on TLR directed adjuvants

Patent applications on TLR4-directed or other TLR-directed adjuvants (M38)

BactiVax LinkedIn group

BactiVax LinkedIn Group established and all members of the consortium following the group LMU will lead this and will be supported by CNRIBB

Patent application: Effective bicyclic peptide vaccine

EPFL will file patents on the most effective bicyclic peptide vaccines

Protocols: novel NMR methods to explore molecu-lar recognition processes to target

Protocols novel NMR methods to explore molecular recognition processes to target mechanism of action of TLR agonists There will be two drafts of the protocols at month 24 and 36

Publications submitted on effective vaccine antigens

Publications submitted on effective vaccine antigens (M40, M46). UCD, QUB, LMU and Lio will submit papers on their own antigens with co-authors from the consortium as appropriate

Publication submitted: Immune responses to vaccine formulations

Publication: Innate and acquired (T-cell and B cell) responses to adjuvanted vaccine formulations. It is antcipated that Imperial and CIC-BioGune will be co-authors on this publication with other authors as relevant.

Report on Vaccine advocacy activities

Reports on Vaccine advocacy activities will be prepared annually at 9 21 33 and 45 months

Communication and Public engagement Plan

Communication and Public Engagement strategy developed and circulated to BactiVax network

Publication submitted on the effect of novel pep-tide-based therapeutic vaccine candidates

Publication submitted on the effect of novel peptide-based therapeutic vaccine candidates will be co-authored by SGUL and ELTE with additional authors from the consortium as appropriate.

Publication submitted: Effective vaccine antigen and adjuvant combinations

Publication: Effective prophylactic and/or therapeutic vaccine-adjuvant combinations against P. aeruginosa and Burkholderia

Potential inputs for policy feedback

We will review the overall outputs from the BactiVax project and will collate relevant outputs that may inform Vaccine policymakers within the Commission and in relevant stakeholders such as WHO and GAVI

Publication on the preparation of multi-epitope peptide conjugates ( formulation of peptide-drug conjugates and adjuvant

Publication on the preparation of multi-epitope peptide conjugates which will describe the formulation of peptide-drug conjugates and adjuvant will be submitted by month 40

Consortium quarterly newsletter (every 4 months)

Consortium quarterly newsletter will be prepared and circulated across the consortium every quarter. It will also be posted on the BactiVax website for maximal public dissemination.

Plan for the Exploitation and Dissemination of results (PEDR) plan

Plan for the Exploitation and Dissemination of results PEDR in place

Pubblicazioni

The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes

Autori: Keren Turton, Hannah J. Parks, Paulina Zarodkiewicz, Mohamad A. Hamad, Rachel Dwane, Georgiana Parau, Rebecca J. Ingram, Rebecca C. Coll, Clare E. Bryant, Miguel A. Valvano
Pubblicato in: Cell Reports, Numero 42, 2024, Pagina/e 113012, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2023.113012

Immunogenicity of PE18, PE31, and PPE26 proteins from Mycobacterium tuberculosis in humans and mice

Autori: María García-Bengoa, Emil Joseph Vergara, Andy C. Tran, Lorenzo Bossi, Andrea M. Cooper, John E. Pearl, Tufária Mussá, Maren von Köckritz-Blickwede, Mahavir Singh, Rajko Reljic
Pubblicato in: Frontiers in Immunology, Numero 14, 2023, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1307429

Structural Basis of PE_PGRS Polymorphism, a Tool for Functional Modulation

Autori: Eliza Kramarska, Flavio De Maio, Giovanni Delogu, Rita Berisio
Pubblicato in: Biomolecules, Numero 13, 2023, Pagina/e 812, ISSN 2218-273X
Editore: MDPI
DOI: 10.3390/biom13050812

Mammalian Neuropeptides as Modulators of Microbial Infections: Their Dual Role in Defense versus Virulence and Pathogenesis

Autori: Daria Augustyniak, Eliza Kramarska, Paweł Mackiewicz, Magdalena Orczyk-Pawiłowicz, Fionnuala T. Lundy
Pubblicato in: International Journal of Molecular Sciences, Numero 22(7), 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22073658

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells

Autori: Flavio De Maio, Alessandro Salustri, Basem Battah, Ivana Palucci, Federica Marchionni, Silvia Bellesi, Valentina Palmieri, Massimiliano Papi, Eliza Kramarska, Maurizio Sanguinetti, Michela Sali, Rita Berisio, and Giovanni Delogu.
Pubblicato in: Virulence, Numero Volume 13, Numero 1, 2022, Pagina/e 868-884, ISSN 2150-5608
Editore: Taylor & Francis
DOI: 10.1080/21505594.2021.1897247

A Global Picture of Molecular Changes Associated to LPS Treatment in THP-1 Derived Human Macrophages by Fourier Transform Infrared Microspectroscopy

Autori: Diletta Ami, Ana Rita Franco, Valentina Artusa, Paolo Mereghetti, Francesco Peri, Antonino Natalello
Pubblicato in: International Journal of Molecular Sciences, Numero 23, 2024, Pagina/e 13447, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232113447

An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria

Autori: Marwa Naguib, Nicolás Feldman, Paulina Zarodkiewicz, Holly Shropshire, Christina Biamis, Omar M. El-Halfawy, Julia McCain, Clément Dezanet, Jean-Luc Décout, Yin Chen, Gonzalo Cosa, Miguel A. Valvano
Pubblicato in: PLOS Biology, Numero 20, 2022, Pagina/e e3001610, ISSN 1545-7885
Editore: PLOS
DOI: 10.1371/journal.pbio.3001610

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

Autori: Andrew O'Connor, Irene Jurado‐Martín, Margaritha M. Mysior, Anotidaishe L. Manzira, Joanna Drabinska, Jeremy C. Simpson, Mary Lucey, Kirsten Schaffer, Rita Berisio, Siobhán McClean
Pubblicato in: MicrobiologyOpen, Numero 12, 2023, ISSN 2045-8827
Editore: John Wiley and Sons Inc.
DOI: 10.1002/mbo3.1311

BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis

Autori: Julen Tomás-Cortázar, Lorenzo Bossi, Conor Quinn, Catherine J. Reynolds, David K. Butler, Niamh Corcoran, Maitiú Ó Murchú, Eve McMahon, Mahavir Singh, Patpong Rongkard, Juan Anguita, Alfonso Blanco, Susanna J. Dunachie, Daniel Altmann, Rosemary J. Boyton, Johan Arnold, Severine Giltaire, Siobhán McClean
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.767359

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Autori: Bognar, Zsolt ; Mothukuri, Ganesh K. ; Nielsen, Alexander L. ; Merz, Manuel L. ; Panzar, Peter M. F. ; Heinis, Christian
Pubblicato in: Organic & Biomolecular Chemistry, 2022, Pagina/e 5699-5703, ISSN 1477-0520
Editore: Royal Society of Chemistry
DOI: 10.1039/d2ob00910b

A Structural View at Vaccine Development against M. tuberculosis

Autori: Maria Romano, Flavia Squeglia, Eliza Kramarska, Giovanni Barra, Han-Gyu Choi, Hwa-Jung Kim, Alessia Ruggiero, Rita Berisio
Pubblicato in: Cells, Numero 12, 2023, Pagina/e 317, ISSN 2073-4409
Editore: Cells
DOI: 10.3390/cells12020317

Marked enhancement of the immunogenicity of plant‐expressed <scp>IgG‐Fc</scp> fusion proteins by inclusion of cholera toxin non‐toxic B subunit within the single polypeptide

Autori: Mi‐Young Kim, Emil Vergara, Andy Tran, Matthew John Paul, Tae‐Ho Kwon, Julian K.C. Ma, Yong‐Suk Jang, Rajko Reljic
Pubblicato in: Plant Biotechnology Journal, Numero 22, 2024, Pagina/e 1402-1416, ISSN 1467-7644
Editore: Blackwell Publishing Inc.
DOI: 10.1111/pbi.14275

Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development

Autori: Samuel T Pasco and Juan Anguita
Pubblicato in: Cells, Numero 9, 2020, Pagina/e E2109, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9092109

Exploring multivalent carbohydrate–protein interactions by NMR

Autori: Jon I. Quintana, Unai Atxabal, Luca Unione, Ana Ardá, Jesús Jiménez-Barbero
Pubblicato in: Chemical Society Reviews, Numero 52, 2024, Pagina/e 1591-1613, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cs00983h

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

Autori: Sevan Habeshian, Manuel Leonardo Merz, Gontran Sangouard, Ganesh Kumar Mothukuri, Mischa Schüttel, Zsolt Bognár, Cristina Díaz-Perlas, Jonathan Vesin, Julien Bortoli Chapalay, Gerardo Turcatti, Laura Cendron, Alessandro Angelini, Christian Heinis
Pubblicato in: Nature Communications, Numero 13, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-31428-8

Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection

Autori: Chiara Bellini, Emil Vergara, Fruzsina Bencs, Kinga Fodor, Szilvia Bősze, Denis Krivić, Bernadett Bacsa, Sára Eszter Surguta, József Tóvári, Rajko Reljic, Kata Horváti
Pubblicato in: Bioconjugate Chemistry, Numero 34, 2023, Pagina/e 1738-1753, ISSN 1043-1802
Editore: American Chemical Society
DOI: 10.1021/acs.bioconjchem.3c00273

Current Status on Therapeutic Molecules Targeting Siglec Receptors

Autori: María Pia Lenza, Unai Atxabal, Iker Oyenarte, Jesús Jiménez-Barbero, June Ereño-Orbea
Pubblicato in: Cells, Numero 9/12, 2020, Pagina/e 2691, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9122691

Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

Autori: Alexander L. Nielsen, Zsolt Bognar, Ganesh K. Mothukuri, Anne Zarda, Mischa Schüttel, Manuel L. Merz, Xinjian Ji, Edward J. Will, Monica Chinellato, Christian R. O. Bartling, Kristian Strømgaard, Laura Cendron, Alessandro Angelini, Christian Heinis
Pubblicato in: Angewandte Chemie Int. Ed., Numero Volume 63, Numero 26, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400350

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants

Autori: Alessio Romerio, Nicole Gotri, Ana Rita Franco, Valentina Artusa, Mohammed Monsoor Shaik, Samuel T. Pasco, Unai Atxabal, Alejandra Matamoros-Recio, Marina Mínguez-Toral, Juan Diego Zalamea, Antonio Franconetti, Nicola G. A. Abrescia, Jesus Jimenez-Barbero, Juan Anguita, Sonsoles Martín-Santamaría, Francesco Peri
Pubblicato in: Journal of Medicinal Chemistry, Numero 66, 2023, Pagina/e 3010-3029, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/acs.jmedchem.2c01998

Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists

Autori: Diletta Ami, Ana Rita Franco, Valentina Artusa, Alessio Romerio, Mohammed Monsoor Shaik, Alice Italia, Juan Anguita, Samuel Pasco, Paolo Mereghetti, Francesco Peri, Antonino Natalello
Pubblicato in: Talanta, Numero 275, 2024, Pagina/e 126104, ISSN 0039-9140
Editore: Elsevier BV
DOI: 10.1016/j.talanta.2024.126104

Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling

Autori: Unai Atxabal, Corwin Nycholat, Johannes M. Pröpster, Andrea Fernández, Iker Oyenarte, Maria Pia Lenza, Antonio Franconetti, Cátia O. Soares, Helena Coelho, Filipa Marcelo, Mario Schubert, James C. Paulson, Jesús Jiménez-Barbero, June Ereño-Orbea
Pubblicato in: ACS Chemical Biology, Numero 19, 2024, Pagina/e 483-496, ISSN 1554-8929
Editore: American Chemical Society
DOI: 10.1021/acschembio.3c00664

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

Autori: Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, Klaudia Sobczak, Felix Elortza, James D. Sutherland, Rosa Barrio, Filipa Marcelo, Jesús Jiménez-Barbero, Asis Palazon, June Ereño-Orbea
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39119-8

Recent Advances in the Development of Protein- and Peptide-Based Subunit Vaccines against Tuberculosis

Autori: Chiara Bellini and Kata Horváti
Pubblicato in: Cells, Numero 9/12, 2020, Pagina/e 2673, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9122673

Current Advances in Burkholderia Vaccines Development

Autori: Guanbo Wang, Paulina Zarodkiewicz, Miguel A. Valvano
Pubblicato in: Cells, Numero 9/12, 2020, Pagina/e 2671, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9122671

Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae

Autori: Barbara Maciejewska, Flavia Squeglia, Agnieszka Latka, Mario Privitera, Sebastian Olejniczak, Paulina Switala, Alessia Ruggiero, Daniela Marasco, Eliza Kramarska, Zuzanna Drulis-Kawa, Rita Berisio
Pubblicato in: mBio, Numero 14, 2024, ISSN 2150-7511
Editore: American Society for Microbiology
DOI: 10.1128/mbio.01329-23

Overcoming Challenges in Chemical Glycosylation to Achieve Innovative Vaccine Adjuvants Possessing Enhanced TLR4 Activity

Autori: Alessio Romerio, Ana Rita Franco, Melanie Shadrick, Mohammed Monsoor Shaik, Valentina Artusa, Alice Italia, Federico Lami, Alexei V. Demchenko, Francesco Peri
Pubblicato in: ACS Omega, Numero 8, 2023, Pagina/e 36412-36417, ISSN 2470-1343
Editore: ACS Omega
DOI: 10.1021/acsomega.3c05363

A modified mycobacterial growth inhibition assay for the functional assessment of vaccine-mediated immunity

Autori: Emil Joseph Vergara, Andy Cano Tran, Matthew J. Paul, Thomas Harrison, Andrea Cooper, Rajko Reljic
Pubblicato in: npj Vaccines, Numero 9, 2024, ISSN 2059-0105
Editore: Springer Nature
DOI: 10.1038/s41541-024-00906-z

Role of phagocyte extracellular traps during Mycobacterium tuberculosis infections and tuberculosis disease processes

Autori: María García-Bengoa, Marita Meurer, Ralph Goethe, Mahavir Singh, Rajko Reljic, Maren von Köckritz-Blickwede
Pubblicato in: Frontiers in Microbiology, Numero 14, 2023, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2023.983299

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

Autori: Irene Jurado-Martín, Maite Sainz-Mejías, Siobhán McClean
Pubblicato in: International Journal of Molecular Sciences, Numero 22/6, 2021, Pagina/e 3128, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22063128

Implications of O-glycan modifications in the hinge region of a plant-produced SARS-CoV-2-IgA antibody on functionality

Autori: Pia Uetz, Kathrin Göritzer, Emil Vergara, Stanislav Melnik, Clemens Grünwald-Gruber, Rudolf Figl, Ala-Eddine Deghmane, Elisabetta Groppelli, Rajko Reljic, Julian K.-C. Ma, Eva Stöger, Richard Strasser
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 12, 2024, ISSN 2296-4185
Editore: Frontiers in Bioengineering and Biotechnology
DOI: 10.3389/fbioe.2024.1329018

Quantifying Siglec-sialylated ligand interactions: a versatile 19F-T2 CPMG filtered competitive NMR displacement assay

Autori: Unai Atxabal, Andrea Fernández, Maria Jesús Moure, Klaudia Sobczak, Corwin Nycholat, Verónica Almeida-Marrero, Iker Oyenarte, James C. Paulson, Andrés de la Escosura, Tomás Torres, Niels C. Reichardt, Jesús Jiménez-Barbero, June Ereño-Orbea
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 10612-10624, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc01723d

Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps

Autori: María García-Bengoa, Marita Meurer, Matthias Stehr, Ayssar A. Elamin, Mahavir Singh, Wulf Oehlmann, Matthias Mörgelin, Maren von Köckritz-Blickwede
Pubblicato in: Frontiers in Immunology, Numero 14, 2023, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1206529

Predictive and Experimental Immunogenicity of Burkholderia Collagen-like Protein 8-Derived Antigens

Autori: Megan E. Grund, Eliza Kramarska, Soo Jeon Choi, Dudley H. McNitt, Christopher P. Klimko, Nathaniel O. Rill, Jennifer L. Dankmeyer, Jennifer L. Shoe, Melissa Hunter, David P. Fetterer, Zander M. Hedrick, Ivan Velez, Sergei S. Biryukov, Christopher K. Cote, Rita Berisio, Slawomir Lukomski
Pubblicato in: MDPI Vaccines, Numero 9(11), 2021, Pagina/e 1219, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9111219

Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive ESKAPE pathogens

Autori: Océane Sadones, Eliza Kramarska, Diana Laverde, Rita Berisio, Johannes Huebner, Felipe Romero-Saavedra
Pubblicato in: BMC Microbiology, Numero 24, 2024, ISSN 1471-2180
Editore: BioMed Central
DOI: 10.1186/s12866-024-03427-w

Mucosal and systemic immune responses after a single intranasal dose of nanoparticle and spore-based subunit vaccines in mice with pre-existing lung mycobacterial immunity

Autori: Emil Joseph Vergara, Andy Cano Tran, Mi-Young Kim, Tufária Mussá, Matthew J. Paul, Thomas Harrison, Rajko Reljic
Pubblicato in: Frontiers in Immunology, Numero 14, 2023, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1306449

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

Autori: Ainize Peña-Cearra, Ainhoa Palacios, Aize Pellon, Janire Castelo, Samuel Tanner Pasco, Iratxe Seoane, Diego Barriales, Jose Ezequiel Martin, Miguel Ángel Pascual-Itoiz, Monika Gonzalez-Lopez, Itziar Martín-Ruiz, Nuria Macías-Cámara, Naiara Gutiez, Sarai Araujo-Aris, Ana Mª Aransay, Héctor Rodríguez, Juan Anguita, Leticia Abecia
Pubblicato in: Communications Biology, Numero 7, 2024, ISSN 2399-3642
Editore: Communications Biology
DOI: 10.1038/s42003-024-05867-6

Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies

Autori: Ana Rita Franco, Océane Sadones, Alessio Romerio, Valentina Artusa, Mohammed Monsoor Shaik, Samuel T. Pasco, Alice Italia, Simona D’Amato, Juan Anguita, Johannes Huebner, Felipe Romero-Saavedra, Francesco Peri
Pubblicato in: Journal of Medicinal Chemistry, Numero 67, 2024, Pagina/e 5603-5616, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c02215

Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody

Autori: Maria Pia Lenza, Unai Atxabal, Corwin Nycholat, Iker Oyenarte, Antonio Franconetti, Jon Imanol Quintana, Sandra Delgado, Reyes Núñez-Franco, Carmen Teresa Garnica Marroquín, Helena Coelho, Luca Unione, Gonzalo Jiménez-Oses, Filipa Marcelo, Mario Schubert, James C. Paulson, Jesús Jiménez-Barbero, June Ereño-Orbea
Pubblicato in: JACS Au, Numero 3, 2023, Pagina/e 204-215, ISSN 2691-3704
Editore: American Chemical Society
DOI: 10.1021/jacsau.2c00592

Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

Autori: Naroa Goikoetxea‐Usandizaga, Marina Serrano‐Maciá, Teresa C. Delgado, Jorge Simón, David Fernández Ramos, Diego Barriales, Maria E. Cornide, Mónica Jiménez, Marina Pérez‐Redondo, Sofia Lachiondo‐Ortega, Rubén Rodríguez‐Agudo, Maider Bizkarguenaga, Juan Diego Zalamea, Samuel T. Pasco, Daniel Caballero‐Díaz, Benedetta Alfano, Miren Bravo, Irene González‐Recio, Maria Mercado
Pubblicato in: Hepatology, Numero 75, 2024, Pagina/e 550-566, ISSN 0270-9139
Editore: John Wiley & Sons Inc.
DOI: 10.1002/hep.32149

Serological analysis reveals differential antibody responses between TB patients and latently infected individuals from the TB endemic country of Mozambique

Autori: Andy C. Tran, Eugenia Boariu, María García-Bengoa, Mi-Young Kim, Emil Joseph Vergara, Tufária Mussá, Rajko Reljic
Pubblicato in: Frontiers in Medicine, Numero 10, 2023, ISSN 2296-858X
Editore: Frontiers in Medicine
DOI: 10.3389/fmed.2023.1286785

Understanding Pseudomonas aeruginosa–Host Interactions: The Ongoing Quest for an Efficacious Vaccine

Autori: Maite Sainz-Mejías, Irene Jurado-Martín, Siobhán McClean
Pubblicato in: Cells, Numero 9/12, 2020, Pagina/e 2617, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9122617

PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response

Autori: Eliza Kramarska, Flavia Squeglia, Flavio De Maio, Giovanni Delogu, Rita Berisio
Pubblicato in: Cells, Numero 10/1, 2021, Pagina/e 161, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10010161

Developing New Anti-Tuberculosis Vaccines: Focus on Adjuvants

Autori: Ana Rita Franco, Francesco Peri
Pubblicato in: Cells, Numero 10/1, 2021, Pagina/e 78, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10010078

Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking

Autori: Ana Rita Franco, Valentina Artusa, Francesco Peri
Pubblicato in: Methods in Molecular Biology, Toll-Like Receptors, 2023, Pagina/e 57-74, ISBN 978-1-0716-3366-3
Editore: Springer US
DOI: 10.1007/978-1-0716-3366-3_3

Nuclear Magnetic Resonance Techniques for the Study of Glycan Interactions

Autori: Unai Atxabal, Ana Gimeno, Jesús Jiménez-Barbero
Pubblicato in: Comprehensive Glycoscience, 2024, Pagina/e 329-345, ISBN 9780128222447
Editore: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00015-8

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METHOD FOR PREPARING A LIBRARY OF PEPTIDES OR A PEPTIDE

Numero candidatura/pubblicazione: 20 22061138
Data: 2022-04-27
Candidato/i: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

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