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ADAMtx: Development of Alzheimer’s immunotherapy by harnessing the natural reparative properties of microglia

Project description

Fighting Alzheimer's using the natural immunotherapeutic potential of brain cells

Alzheimer's disease is caused by multiple detrimental factors leading to cognitive decline. Currently, no effective treatment exists for this disease, as targeting any single factor could not stop or reverse the disease, as evident in the multiple failures seen in recent clinical trials. The EU-funded ADAMtx project aims to develop a novel approach for comprehensive treatment. Previously, project members had discovered immuno-competent brain microglia cells (disease associated microglia) that specifically fight neurodegenerative diseases. In the current project, researchers will develop several different targets that stimulate activity in these microglia cells. The ultimate goal of the team is to establish intellectual property and take on the development of the targets by involving venture capitalists and establishing a start-up company.

Call for proposal

ERC-2019-PoC
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Host institution

WEIZMANN INSTITUTE OF SCIENCE
Address
Herzl Street 234
7610001 Rehovot
Israel
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 150 000

Beneficiaries (1)

WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 150 000
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments