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Process Analytical Technologies for Industrial Nanoparticle Production

Project description

Innovative tools for nanoparticle size analysis

While bulk materials have constant physical properties independent of their size, the physical and chemical properties of a nanoparticle are dictated by its size. Accurate characterisation of mean size, size distribution and shape is key to the efficient manufacturing of high-quality nanomaterials. The EU-funded NanoPAT project plans to use three new real-time analytical tools that overcome problems and limitations of conventional characterisation technologies. The new process analytical technologies (PAT) will be photon density wave spectroscopy, optofluidic force induction and turbidity spectrometry. The innovative technologies will be combined with new data analysis methods to provide, for the first time, real-time analysis of particles on the nanometre scale with sub-minute temporal resolution.


Nano-scaled materials are abundant in different stages of industrial manufacturing. Physical and chemical properties of these materials are strongly dependent on their size. Characterisation of mean size, size distribution, and shape of nano-scaled particles is very critical for the quality and efficiency of manufacturing processes. Yet, conventional characterisation technologies still show manifold shortcomings which represent a major innovation obstacle for manufacturers of nanoparticles. The NanoPAT consortium aims at closing this gap by the demonstration of 3 novel, real-time nano-characterisation Process Analytical Technologies (PAT), namely Photon Density Wave spectroscopy (PDW), OptoFluidic force induction (OF2i) and Turbidity spectrometry (TUS) including real-time data handling for digital process monitoring and product quality control. Those will be validated in 5 different industrial ceramic, polymer and mineral nanoparticles manufacturing and converting environments. This implies that innovating PATs will be paired with new data-analytical technologies in order to provide, for the first time, a real-time analysis for manufacturing processes of particles in the nanometer scale with sub minute temporal resolution. The NanoPAT consortium consists of 14 members, representing instrument developers, process data and modelling experts, academic process researchers, industrial processing experts, as well as innovation and dissemination specialists. The consortium profits from the broad involvement of its members in EU networks and ongoing H2020 projects. NanoPAT will intensively contribute to enhancing the innovation capacity of the European nanotechnology sector. As a result, the NanoPAT real-time nano-characterisation technologies will have reached TRL 6, promising valuable improvements in terms of quality, productivity and sustainability for the process industries in the EU and beyond.

Call for proposal


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Net EU contribution
€ 810 000,00
Carretera d esplugues 39 41
08940 Cornella de llobregat

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Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Participants (17)