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Handheld optical coherence tomography

Objective

Optical coherence tomography (OCT) is a revolutionizing in-vivo 3D imaging technique for non-invasive optical biopsy addressing medical needs in early diagnosis and effective disease management. OCT has proven its value primarily in ophthalmology but more recently also in a variety of other medical fields. However, wide adoption in health care, a requirement for effective therapy control, has not taken place mainly due to cost limitations and the non-existence of miniaturized mobile devices. Integrated photonics is expected to leverage off many advances made in integrated electronics. Based on photonic integrated circuit technology, HandheldOCT will enable a new generation of handheld OCT systems in the 1060nm wavelength region for optimum tissue penetration with step-changes in imaging performance (4x faster imaging speed), with size (10x smaller) and cost (2-5x cheaper) beyond state-of-the-art. The monolithic integration of silicon nitride optical waveguides, Germanium photodiodes, and micro-optics combined with the hybrid integration of a novel compact all-semiconductor akinetic swept source will enable a mobile, low-cost solution of high usability. HandheldOCT is expected to contribute significantly to a widespread adoption of OCT in point-of-care diagnostics (e.g. for new-born, children, bedridden elderly, home remote diagnosis) and for diagnostic-driven therapy of major sight-threatening, mostly age-related retinal pathologies with the aim to improve patient outcome and reduce healthcare costs. The endeavour is strongly driven by companies and research organisations with solid expertise in silicon foundry technology, miniaturized laser sources, photonic design and packaging, electronics, and medical OCT system integration. The consortium includes clinicians and the world-leading ophthalmic equipment manufacturer focusing on implementing diagnostically relevant specifications and the translational clinical proof-of-principle testing on a small patient cohort.

Field of science

  • /medical and health sciences/clinical medicine/ophthalmology
  • /natural sciences/chemical sciences/inorganic chemistry/inorganic compounds

Call for proposal

H2020-ICT-2019-2
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Address
Spitalgasse 23
1090 Wien
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 786 820

Participants (6)

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
EU contribution
€ 723 278,75
Address
Giefinggasse 4
1210 Wien
Activity type
Research Organisations
INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM
Belgium
EU contribution
€ 1 600 751,25
Address
Kapeldreef 75
3001 Leuven
Activity type
Research Organisations
INNOLUME GMBH
Germany
EU contribution
€ 933 750
Address
Konrad-adenauer-allee 11
44263 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
EU contribution
€ 592 567,50
Address
Western Road
T12 YN60 Cork
Activity type
Higher or Secondary Education Establishments
NANOSCRIBE GMBH
Germany
EU contribution
€ 353 751,25
Address
Hermann Von Helmholtzplatz 6
76344 Eggenstein-leopoldshafen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CARL ZEISS AG
Germany
EU contribution
€ 995 060
Address
Carl Zeiss Strasse 22
73447 Oberkochen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)