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Handheld optical coherence tomography

Objective

Optical coherence tomography (OCT) is a revolutionizing in-vivo 3D imaging technique for non-invasive optical biopsy addressing medical needs in early diagnosis and effective disease management. OCT has proven its value primarily in ophthalmology but more recently also in a variety of other medical fields. However, wide adoption in health care, a requirement for effective therapy control, has not taken place mainly due to cost limitations and the non-existence of miniaturized mobile devices. Integrated photonics is expected to leverage off many advances made in integrated electronics. Based on photonic integrated circuit technology, HandheldOCT will enable a new generation of handheld OCT systems in the 1060nm wavelength region for optimum tissue penetration with step-changes in imaging performance (4x faster imaging speed), with size (10x smaller) and cost (2-5x cheaper) beyond state-of-the-art. The monolithic integration of silicon nitride optical waveguides, Germanium photodiodes, and micro-optics combined with the hybrid integration of a novel compact all-semiconductor akinetic swept source will enable a mobile, low-cost solution of high usability. HandheldOCT is expected to contribute significantly to a widespread adoption of OCT in point-of-care diagnostics (e.g. for new-born, children, bedridden elderly, home remote diagnosis) and for diagnostic-driven therapy of major sight-threatening, mostly age-related retinal pathologies with the aim to improve patient outcome and reduce healthcare costs. The endeavour is strongly driven by companies and research organisations with solid expertise in silicon foundry technology, miniaturized laser sources, photonic design and packaging, electronics, and medical OCT system integration. The consortium includes clinicians and the world-leading ophthalmic equipment manufacturer focusing on implementing diagnostically relevant specifications and the translational clinical proof-of-principle testing on a small patient cohort.

Call for proposal

H2020-ICT-2018-20

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Sub call

H2020-ICT-2019-2

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Net EU contribution
€ 786 820,00
Address
Spitalgasse 23
1090 Wien
Austria

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (8)

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
Net EU contribution
€ 723 278,75
Other funding
€ 0,00
INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM
Belgium
Net EU contribution
€ 1 600 751,25
Address
Kapeldreef 75
3001 Leuven

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Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Research Organisations
Other funding
€ 0,00
INNOLUME GMBH
Germany
Net EU contribution
€ 933 750,00
Address
Konrad Adenauer Allee 11
44263 Dortmund

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
Net EU contribution
€ 592 567,50
Address
Western Road
T12 YN60 Cork

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
NANOSCRIBE GMBH

Participation ended

Germany
Net EU contribution
€ 70 658,65
Address
Hermann Von Helmholtzplatz 6
76344 Eggenstein-leopoldshafen
Region
Baden-Württemberg Karlsruhe Karlsruhe, Landkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
CARL ZEISS AG
Germany
Net EU contribution
€ 935 060,00
Address
Carl Zeiss Strasse 22
73447 Oberkochen

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Region
Baden-Württemberg Stuttgart Ostalbkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CARL ZEISS JENA GMBH
Germany
Net EU contribution
€ 60 000,00
Address
Carl-zeiss-promenade 10
07745 Jena

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Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
NANOSCRIBE GMBH & CO KG
Germany
Net EU contribution
€ 283 092,60
Address
Hermann-von-helmholtz-platz 6
76344 Eggenstein-leopoldshafen

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Region
Baden-Württemberg Karlsruhe Karlsruhe, Landkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00