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Handheld optical coherence tomography

Ziel

Optical coherence tomography (OCT) is a revolutionizing in-vivo 3D imaging technique for non-invasive optical biopsy addressing medical needs in early diagnosis and effective disease management. OCT has proven its value primarily in ophthalmology but more recently also in a variety of other medical fields. However, wide adoption in health care, a requirement for effective therapy control, has not taken place mainly due to cost limitations and the non-existence of miniaturized mobile devices. Integrated photonics is expected to leverage off many advances made in integrated electronics. Based on photonic integrated circuit technology, HandheldOCT will enable a new generation of handheld OCT systems in the 1060nm wavelength region for optimum tissue penetration with step-changes in imaging performance (4x faster imaging speed), with size (10x smaller) and cost (2-5x cheaper) beyond state-of-the-art. The monolithic integration of silicon nitride optical waveguides, Germanium photodiodes, and micro-optics combined with the hybrid integration of a novel compact all-semiconductor akinetic swept source will enable a mobile, low-cost solution of high usability. HandheldOCT is expected to contribute significantly to a widespread adoption of OCT in point-of-care diagnostics (e.g. for new-born, children, bedridden elderly, home remote diagnosis) and for diagnostic-driven therapy of major sight-threatening, mostly age-related retinal pathologies with the aim to improve patient outcome and reduce healthcare costs. The endeavour is strongly driven by companies and research organisations with solid expertise in silicon foundry technology, miniaturized laser sources, photonic design and packaging, electronics, and medical OCT system integration. The consortium includes clinicians and the world-leading ophthalmic equipment manufacturer focusing on implementing diagnostically relevant specifications and the translational clinical proof-of-principle testing on a small patient cohort.

Aufforderung zur Vorschlagseinreichung

H2020-ICT-2019-2
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MEDIZINISCHE UNIVERSITAET WIEN
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Spitalgasse 23
1090 Wien
Österreich
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Higher or Secondary Education Establishments
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€ 786 820

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AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Österreich
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€ 723 278,75
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Giefinggasse 4
1210 Wien
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Research Organisations
INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM
Belgien
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€ 1 600 751,25
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Kapeldreef 75
3001 Leuven
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Research Organisations
INNOLUME GMBH
Deutschland
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€ 933 750
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Konrad-adenauer-allee 11
44263 Dortmund
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Irland
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€ 592 567,50
Adresse
Western Road
T12 YN60 Cork
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Higher or Secondary Education Establishments
NANOSCRIBE GMBH

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Deutschland
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€ 70 658,65
Adresse
Hermann Von Helmholtzplatz 6
76344 Eggenstein-leopoldshafen
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
CARL ZEISS AG
Deutschland
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€ 995 060
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Carl Zeiss Strasse 22
73447 Oberkochen
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
NANOSCRIBE GMBH & CO KG
Deutschland
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€ 283 092,60
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Hermann-von-helmholtz-platz 6
76344 Eggenstein-leopoldshafen
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Private for-profit entities (excluding Higher or Secondary Education Establishments)