Nanopeptides and Nanosaccharides for Advanced and Sustainable Materials

Livrables

Seminars held at industries and SME.
Training young scientist on experimental methods for studying tumor adipogenic reprogramming by using nanoparticles

Training young scientist on experimental methods for studying tumor adipogenic reprogramming by using nanoparticles and advanced microscopy techniques

Training ESR on experimental methods

Training ESR on experimental methods for engineering and characterization of PG NPs

Training ESR on theoretical modelling

Training ESR on theoretical modelling and machine learning methods for water based organic NPs

Training young scientists on experimental methods for studying the physico-chemical properties of PG-PNIPAM

Training young scientists on experimental methods for studying the physico-chemical properties of PG-PNIPAM, including AFM and microscopy

"Lecture notes on ""Role of mechanotransduction systems during stem cell differentiation"" and Advanced microscopy for protein tracking"

Lecture notes on Role of mechanotransduction systems during stem cell differentiation and Advanced microscopy for protein tracking

Lecture notes on peptide nanochemistry and ultrasonic technologies.

Lecture notes on peptide nanochemistry and ultrasonic technologies

"Lecture notes on ""rationale design of nanocarriers for biomedical applications"

Lecture notes on rationale design of nanocarriers for biomedical applications

Lecture notes on synthesis of hybrid polymerics materials and microfluidic techniques

Lecture notes on synthesis of hybrid polymerics materials and microfluidic techniques to synthesize microparticles

Training young scientist on different experimental approaches

Training young scientist on different experimental approaches ultrasonic techniques selfassembly LangmuirBlodgett for obtaining peptide nanostructures

Training young scientists on experimental methods for PG-PNIPAM preparation.

Curriculum of interdisciplinary studies on innovation strategies
A set of self-assembling and sono-responsive peptide building blocks.

A set of selfassembling and sonoresponsive peptide building blocks

A library of engineered, functional and versatile PG NPs

A library of engineered functional and versatile PG NPs with controlled properties that can be deployed for various applications

Definition of the best conditions to induce tumor cell cycle and migration arrest by NPs
Definition of conditions to induce tumor adipogenic reprogramming by NPs

Definition of conditions to induce tumor adipogenic reprogramming by NPs.

Nanopeptides with well-defined size, morphology and electroactive properties

Nanopeptides with welldefined size and morphology and electroactive peptidelipid films for biosensing

Complete the synthesis and characterization of PG-PNIPAM bioplastics and nanogels

Complete the synthesis and characterization of PGPNIPAM bioplastics and nanogels

Report on design rules for PG NPs

Report on design rules for PG NPs with tuneable programmable properties

Publications

Formulation matters! A spectroscopic and molecular dynamics investigation on the peptide CIGB552 as itself and in its therapeutical formulation.

Auteurs: M Savioli, L Antonelli, G Bocchinfuso, F Cavalieri, R Cimino, E Gatto et al.
Publié dans: Journal of Peptide Science, 2022, Page(s) 28: e3356, ISSN 1099-1387
Éditeur: Wiley
DOI: 10.1002/psc.3356

Tuning Peptide-Based Hydrogels: Co-Assembly with Composites Driving the Highway to Technological Applications

Auteurs: Valéria Gomes; Sérgio R. S. Veloso; Miguel A. Correa-Duarte; Paula M. T. Ferreira; Elisabete M. S. Castanheira
Publié dans: International Journal of Molecular Sciences, Numéro 1, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24010186

Aggregation properties of a therapeutic peptide for rheumatoid arthritis: A spectroscopic and molecular dynamics study.

Auteurs: Rita Cimino, Marco Savioli, Noemi Ferrante Carrante, Ernesto Placidi, Hilda Garay-Perez, Matilde López-Abad, Alexis Musacchio Lasa, Maria Del Carmen Domínguez-Horta, Emanuela Gatto, Francesca Cavalieri, Gianfranco Bocchinfuso, Mariano Venanzi
Publié dans: ChemPhysMater, 2022, Page(s) 1, 62-70., ISSN 2772-5715
Éditeur: KeAi
DOI: 10.1016/j.chphma.2021.09.007

Peptide Self-Assembled Nanostructures: from Models to Therapeutic Peptides

Auteurs: Emanuela Gatto, Claudio Toniolo and Mariano Venanz
Publié dans: Nanomaterials, 2022, Page(s) 12(3), 466;, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano12030466

An Engineered Nanosugar Enables Rapid and SustainedGlucose-Responsive Insulin Delivery in Diabetic Mice

Auteurs: Rong Xu, Sukhvir Kaur Bhangu, Karly C. Sourris, Domitilla Vanni, Marc-Antoine Sani, John A. Karas, Karen Alt, Be’eri Niego, Anukreity Ale, Quinn A. Besford, Brendan Dyett, Joshua Patrick, Irena Carmichael, Jonathan E. Shaw, Frank Caruso, Mark E. Cooper, Christoph E. Hagemeyer,* and Francesca Cavalieri*
Publié dans: Advanced Materials, 2023, ISSN 1521-4095
Éditeur: Wiley
DOI: 10.1002/adma.202210392

Magnetically propelled chained nanocomposites for biologically relevant media exploration

Auteurs: Miguel A. Ramos-Docampo; Pablo Hurtado; Ana B. Dávila-Ibáñez; Roberto Piñeiro; Mónica L. Fanarraga; Verónica Salgueiriño
Publié dans: J Colloid Interface Sci . Volume 629, Part A, January 2023, Pages 287-296, Numéro 1, 2023, ISSN 0021-9797
Éditeur: Academic Press
DOI: 10.1016/j.jcis.2022.08.154

A spectroscopic and molecular dynamics study on the aggregation process of a long-acting lipidated therapeutic peptide: the case of semaglutide

Auteurs: Mariano Venanzi; Marco Savioli; Rita Cimino; Emanuela Gatto; Antonio Palleschi; Giorgio Ripani; Daniel Oscar Cicero; Ernesto Placidi; F. Orvieto; E. Bianchi
Publié dans: Soft Matter, Numéro 3, 2020, ISSN 1744-683X
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d0sm01011a

Magnetism Engineering in Antiferromagnetic β-FeOOH Nanostructures via Chemically Induced Lattice Defects

Auteurs: Martín Testa-Anta*, Ecem Tiryaki, Laura Bocher, and Verónica Salgueiriño
Publié dans: Chemistry of Materials, Numéro 2, 2023, ISSN 0897-4756
Éditeur: American Chemical Society
DOI: 10.1021/acs.chemmater.2c03067

Triggering the nanophase separation of albumin through multivalent binding to glycogen for drug delivery in 2D and 3D multicellular constructs.

Auteurs: Agata Glab, Sukhvir Kaur Bhangu, Soraia Fernandes, Christina Cortez-Jugo, Robert De Rose, Brendan Dyett, Marcin Wojnilowicz, Petra Laznickova, Jan Fric, Giancarlo Forte, Frank Caruso*, Francesca Cavalieri*
Publié dans: Nanoscale, 2022, Page(s) 14, 3452-3466, ISSN 2040-3372
Éditeur: RCS
DOI: 10.1039/d1nr08429a

Interfaceless Exchange Bias in CoFe<sub>2</sub>O<sub>4</sub> Nanocrystals

Auteurs: Beatriz Rivas-Murias; Martín Testa-Anta; Alexander S. Skorikov; Miguel Comesaña-Hermo; Sara Bals; Verónica Salgueiriño
Publié dans: Nano Letters, Numéro 4, 2023, ISSN 1530-6984
Éditeur: American Chemical Society
DOI: 10.1021/acs.nanolett.2c04268

Oxidative Precipitation Synthesis of Calcium-Doped Manganese Ferrite Nanoparticles for Magnetic Hyperthermia

Auteurs: Sérgio R. S. Veloso , Raquel G. D. Andrade , Valéria Gomes , Carlos O. Amorim , Vítor S. Amaral , Verónica Salgueiriño , Paulo J. G. Coutinho , Paula M. T. Ferreira , Miguel A. Correa-Duarte and Elisabete M. S. Castanheira
Publié dans: International Journal of Molecular Sciences, Numéro 2, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232214145

Tuning the drug multimodal release through a co-assembly strategy based on magnetic gels

Auteurs: Sérgio R. S. Velosoa, Ecem Tiryakib, Carlos Spuchc, Loic Hillioud, C. O. Amorime, V. S. Amarale, Paulo J. G. Coutinhoa, Paula M. T. Ferreiraf, Verónica Salgueiriñob,g*, Miguel A. Correa-Duarteg,*, and Elisabete M. S. Castanheiraa,*
Publié dans: Nanoscale, Numéro 1, 2022, ISSN 2040-3364
Éditeur: Royal Society of Chemistry
DOI: 10.1039/D1NR08158F

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