Automated Cellular Robot-Assisted Technologies for translation of discovery-led research in Osteoarthritis

Project Information

AutoCRAT

Grant agreement ID: 874671

DOI 10.3030/874671

Project closed

EC signature date 2 December 2019

Start date 1 January 2020

End date 30 June 2024

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 7 452 770,00

EU contribution € 7 452 770,00

Coordinated by

UNIVERSITY OF GALWAY
Ireland

Deliverables

Websites, patent fillings, videos etc. (1)

Website and social media

Publications

Peer reviewed articles (8)

"Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a ""therapeutic"" miRNA cargo ameliorating cartilage inflammation in vitro"

Author(s): Palamà, Maria Elisabetta F.; Coco, Simona; Shaw, Georgina M.; Reverberi, Daniele; Ghelardoni, Maddalena; Ostano, Paola; Chiorino, Giovanna; Sercia, Laura; Persano, Luana; Gagliani, Maria Cristina; Cortese, Katia; Pisignano, Dario; Murphy, Josephine Mary; Gentili, Chiara
Published in: Theranostics, Issue 13(5), 2023, Page(s) 1470-1489, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.77597

Scaled preparation of extracellular vesicles from conditioned media

Author(s): Simon Staubach, Fabiola Nardi Bauer, Tobias Tertel, Verena Börger, Oumaima Stambouli, Denise Salzig, Bernd Giebel
Published in: Advanced Drug Delivery Reviews, Issue 177, 2021, Page(s) 113940, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2021.113940

Additively Manufactured Robot Gripper Blades for Automated Cell Production Processes

Author(s): Biermann, F.; Gräfe, S.; Bergs, T.; Schmitt, R.H.
Published in: Processes, Issue 10(10), 2080, 2022, ISSN 2227-9717
Publisher: MDPI
DOI: 10.3390/pr10102080

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

Author(s): Alejandro Rodríguez Ruiz, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen, Christian Freund, Christine L. Mummery, Valeria Orlova, Farshid Guilak, Ingrid Meulenbelt, Yolande F. M. Ramos
Published in: Cell and Tissue Research, 2021, ISSN 0302-766X
Publisher: Springer Verlag
DOI: 10.1007/s00441-021-03498-5

Automated Production at Scale of Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells, Chondrocytes and Extracellular Vehicles: Towards Real-Time Release

Author(s): Laura Herbst, Ferdinand Groten, Mary Murphy, Georgina Shaw, Bastian Nießing, and Robert H. Schmitt
Published in: Processes, 2023, ISSN 2227-9717
Publisher: MDPI
DOI: 10.3390/pr11102938

Role of extracellular vesicles from adipose tissue- and bone marrow-mesenchymal stromal cells in endothelial proliferation and chondrogenesis

Author(s): Cansu Gorgun, Maria Elisabetta Federica Palamà, Daniele Reverberi, Maria Cristina Gagliani, Katia Cortese, Roberta Tasso, Chiara Gentili
Published in: STEM CELLS Transl Med, Issue Volume10, Issue12 December 2021, 2021, Page(s) Pages 1680-1695, ISSN 2157-6564
Publisher: AlphaMed Press
DOI: 10.1002/sctm.21-0107

Insights into the present and future of cartilage regeneration and joint repair

Author(s): H. Evenbratt, L. Andreasson, V. Bicknell, M. Brittberg, R. Mobini and S. Simonsson
Published in: Cell Regeneration, Issue volume 11, Article number: 3, 2022, ISSN 2045-9769
Publisher: Springer Natiure
DOI: 10.1186/s13619-021-00104-5

Characterizing the secretome of licensed hiPSC-derived MSCs

Author(s): Yolande F. M. Ramos; Tobias Tertel; Georgina Shaw; Simon Staubach; Rodrigo Coutinho de Almeida; Eka Suchiman; Thomas B. Kuipers; Hailiang Mei; Frank Barry; Mary Murphy; Bernd Giebel; Ingrid Meulenbelt
Published in: Stem Cell Research & Therapy, Issue 17576512, 2022, ISSN 1757-6512
Publisher: BioMed Central
DOI: 10.1186/s13287-022-03117-2