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New Generation Cell Therapy: Bioartificial Pancreas to Cure Type 1 Diabetes

Project description

Pancreatic organoid could end insulin injections for type 1 diabetes

The food we eat supplies our bodies with critical energy throughout the day. Digested food enters the bloodstream as glucose, to be absorbed by other cells with the help of insulin, a hormone secreted by the pancreas. In diabetes, circulating blood glucose levels are too high. Type 2 diabetes, attributable to diminished capacity to make or use insulin, is treated with lifestyle changes and oral medication. In type 1 diabetes, however, the pancreas makes no insulin at all, and daily insulin shots are required. The EU-funded VANGUARD project is developing an implantable artificial pancreas, an insulin-producing organoid of biological origin. Just the right combination of cell types and hydrogel will encourage growth and vascularisation of functional tissue, and ensure biocompatibility, safety and efficacy. The team plans to make the treatment accessible to all patients.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2019-Single-Stage-RTD

Coordinator

UNIVERSITE DE GENEVE
Net EU contribution
€ 1 995 946,25
Address
Rue Du General Dufour 24
1211 Geneve
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (8)

UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO
Italy
Net EU contribution
€ 936 875,00
Address
Duomo 6
13100 Vercelli

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Region
Nord-Ovest Piemonte Vercelli
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITE LYON 1 CLAUDE BERNARD
France
Net EU contribution
€ 523 812,50
Address
Boulevard Du 11 Novembre 1918 Num43
69622 Villeurbanne Cedex

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Region
Auvergne-Rhône-Alpes Rhône-Alpes Rhône
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
OSPEDALE SAN RAFFAELE SRL
Italy
Net EU contribution
€ 1 049 500,00
Address
Via Olgettina 60
20132 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 804 375,00
Address
Geschwister Scholl Platz 1
80539 Muenchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KUGELMEIERS AG
Switzerland
Net EU contribution
€ 701 250,00
Address
Bahnhofstrasse 40
8703 Erlenbach

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION
Netherlands
Net EU contribution
€ 55 000,00
Address
Westerdoksdijk 423
1013 BX Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Other
Non-EU contribution
€ 0,00
ACCELOPMENT SCHWEIZ AG
Switzerland
Net EU contribution
€ 384 750,00
Address
Seefeldstrasse 198
8008 Zurich

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
Net EU contribution
€ 393 116,25
Address
Dr Molewaterplein 40
3015 GD Rotterdam

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00