CORDIS
EU research results

CORDIS

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New Generation Cell Therapy: Bioartificial Pancreas to Cure Type 1 Diabetes

Project information

Grant agreement ID: 874700

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.3.

  • Overall budget:

    € 6 844 625

  • EU contribution

    € 6 844 625

Coordinated by:

UNIVERSITE DE GENEVE

Switzerland

Project description

English EN

Pancreatic organoid could end insulin injections for type 1 diabetes

The food we eat supplies our bodies with critical energy throughout the day. Digested food enters the bloodstream as glucose, to be absorbed by other cells with the help of insulin, a hormone secreted by the pancreas. In diabetes, circulating blood glucose levels are too high. Type 2 diabetes, attributable to diminished capacity to make or use insulin, is treated with lifestyle changes and oral medication. In type 1 diabetes, however, the pancreas makes no insulin at all, and daily insulin shots are required. The EU-funded VANGUARD project is developing an implantable artificial pancreas, an insulin-producing organoid of biological origin. Just the right combination of cell types and hydrogel will encourage growth and vascularisation of functional tissue, and ensure biocompatibility, safety and efficacy. The team plans to make the treatment accessible to all patients.

Coordinator

UNIVERSITE DE GENEVE

Address

Rue Du General Dufour 24
1211 Geneve

Switzerland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 995 946,25

Participants (8)

UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO

Italy

EU Contribution

€ 936 875

UNIVERSITE LYON 1 CLAUDE BERNARD

France

EU Contribution

€ 523 812,50

OSPEDALE SAN RAFFAELE SRL

Italy

EU Contribution

€ 1 049 500

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Germany

EU Contribution

€ 804 375

KUGELMEIERS AG

Switzerland

EU Contribution

€ 701 250

EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION

Netherlands

EU Contribution

€ 55 000

ACCELOPMENT AG

Switzerland

EU Contribution

€ 384 750

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 393 116,25

Project information

Grant agreement ID: 874700

Status

Ongoing project

  • Start date

    1 January 2020

  • End date

    31 December 2024

Funded under:

H2020-EU.3.1.3.

  • Overall budget:

    € 6 844 625

  • EU contribution

    € 6 844 625

Coordinated by:

UNIVERSITE DE GENEVE

Switzerland