New Generation Cell Therapy: Bioartificial Pancreas to Cure Type 1 Diabetes

Deliverables

Documents, reports (2)

VANGUARD Communication Portfolio

ACCEL will create a communication portfolio of updated VANGUARD print visual and media information and documentation including factsheets brochures and posters and visual content will be developed to offer information about the project in a condensed form that can be handed out during various events and downloaded from the project website

Project website

To support aforementioned dissemination and communication activities throughout the duration of the project, ACCEL will set up and maintain the project website, which will notably function as the main source of information and resources related to the project, partners, latest developments, publications and public deliverables for all stakeholders.

Publications

Peer reviewed articles (14)

Mechanisms of Immunomodulation and Cytoprotection Conferred to Pancreatic Islet by Human Amniotic Epithelial Cells

Author(s): Lebreton F, Hanna R, Wassmer CH, Bellofatto K, Perez L, Othenin-Girard V, de Tejada BM, Cohen M, Berishvili E.
Published in: Stem Cell Reviews and Reports, 18, 2021, Page(s) 346-359, ISSN 1550-8943
Publisher: Springer Verlag
DOI: 10.1007/s12015-021-10269-w

Targeting Toll-Like Receptor 4: a promising strategy to prevent type 1 diabetes occurrence or recurrence

Author(s): Alibashe-Ahmed M., Berney T., Giovannoni L., Berishvili E.
Published in: CellR4, 8, 2020, ISSN 2329-7042
Publisher: Verduci International
DOI: 10.32113/cellr4_20205_2850

Immunomodulatory Properties of Amniotic Membrane Derivatives and Their Potential in Regenerative Medicine

Author(s): Charles-Henri Wassmer, Ekaterine Berishvili
Published in: Current Diabetes Reports, 20/8, 2020, Page(s) 31, ISSN 1534-4827
Publisher: Current Science Inc.
DOI: 10.1007/s11892-020-01316-w

Generation of insulin‐secreting organoids: a step toward engineering and transplanting the bioartificial pancreas

Author(s): Charles‐Henri Wassmer, Fanny Lebreton, Kevin Bellofatto, Domenico Bosco, Thierry Berney, Ekaterine Berishvili
Published in: Transplant International, 33/12, 2020, Page(s) 1577-1588, ISSN 0934-0874
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/tri.13721

Organoids: a systematic review of ethical issues

Author(s): Dide de Jongh, Emma K. Massey , the VANGUARD consortium*, Eline M. Bunnik
Published in: Stem Cell Research & Therapy, 13, 2022, Page(s) 337, ISSN 1757-6512
Publisher: BioMed Central
DOI: 10.1186/s13287-022-02950-9

Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy

Author(s): Ekaterine Berishvili, Laurent Kaiser, Marie Cohen, Thierry Berney, Hanne Scholz, Yngvar Floisand, Jonas Mattsson
Published in: Stem Cell Reviews and Reports, 17/1, 2021, Page(s) 63-70, ISSN 2629-3277
Publisher: Springer
DOI: 10.1007/s12015-020-10004-x

Early-Phase Clinical Trials of Bio-Artificial Organ Technology: A Systematic Review of Ethical Issues

Author(s): de Jongh, D., Massey, E. K., Cronin, A. J., Schermer, M. H. N., Bunnik, E. M. and the VANGUARD Consortium
Published in: Transplant International, 14322277, 2022, ISSN 1432-2277
Publisher: Frontiers Publishing Partnership
DOI: 10.3389/ti.2022.10751

Engineering of Primary Pancreatic Islet Cell Spheroids for Three-dimensional Culture or Transplantation: A Methodological Comparative Study

Author(s): Charles-Henri Wassmer, Kevin Bellofatto, Lisa Perez, Vanessa Lavallard, David Cottet-Dumoulin, Sanda Ljubicic, Géraldine Parnaud, Domenico Bosco, Ekaterine Berishvili, Fanny Lebreton
Published in: Cell Transplantation, 29, 2020, Page(s) 096368972093729, ISSN 0963-6897
Publisher: Cognizant Communication Corp.
DOI: 10.1177/0963689720937292

Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device

Author(s): Olgasi, C., Borsotti, C., Merlin, S., Bergmann, T., Bittorf, P., Adewoye, A. B., Wragg, N., Patterson, K., Calabria, A., Benedicenti, F., Cucci, A., Borchiellini, A., Pollio, B., Montini, E., Mazzuca, D. M., Zierau, M., Stolzing, A., Toleikis, P., Braspenning, J., & Follenzi, A.
Published in: Molecular Therapy - Methods & Clinical Development, 23, 2021, Page(s) 551-566, ISSN 2329-0501
Publisher: Cell Press
DOI: 10.1016/j.omtm.2021.10.015

Mechanisms of Immunomodulation and Cytoprotection Conferred to Pancreatic Islet by Human Amniotic Epithelial Cells.

Author(s): Fanny Lebreton; Reine Hanna; Charles H Wassmer; Kevin Bellofatto; Lisa Perez; Véronique Othenin-Girard; Begoña Martinez de Tejada; Marie Cohen; Ekaterine Berishvili
Published in: Stem Cell Reviews and Reports, 18, 2021, Page(s) 346-359, ISSN 1550-8943
Publisher: Springer Verlag
DOI: 10.1007/s12015-021-10269-w

Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells

Author(s): Pignatelli C, Campo F, Neroni A, Piemonti L and Citro A
Published in: Transplant International, 14322277, 2022, ISSN 1432-2277
Publisher: Frontiers
DOI: 10.3389/ti.2022.10555

Advances and challenges of endocrine pancreas bioengineering

Author(s): Hanna, R., & Berishvili, E.
Published in: Current Opinion in Endocrine and Metabolic Research, 23, 100320, 2022, ISSN 2451-9650
Publisher: Elsevier Ltd.
DOI: 10.1016/j.coemr.2022.100320

I’ve got you under my skin

Author(s): Thierry Berney, Ekaterine Berishvili
Published in: Nature Metabolism, 2/10, 2020, Page(s) 993-994, ISSN 2522-5812
Publisher: Nature Research
DOI: 10.1038/s42255-020-0268-8

Bio-Engineering of Pre-Vascularized Islet Organoids for the Treatment of Type 1 Diabetes

Author(s): Wassmer, C.H., Lebreton, F., Bellofatto, K., Perez, L., Cottet-Dumoulin, D., Andres, A., Bosco, D., Berney, T., Othenin-Girard, V., Martinez De Tejada, B., Cohen, M., Follenzi, A., Berishvili, E., and the VANGUARD Consortium
Published in: Transplant International, 35, 2022, ISSN 1432-2277
Publisher: Frontiers
DOI: 10.3389/ti.2021.10214

Non-peer reviewed articles (1)

Organoïdes sécréteurs d’insuline

Author(s): Fanny Lebreton, Charles-Henri Wassmer, Kevin Belofatto, Thierry Berney, Ekaterine Berishvili
Published in: médecine/sciences, 36/10, 2020, Page(s) 879-885, ISSN 0767-0974
Publisher: Editions E D K
DOI: 10.1051/medsci/2020129

Conference proceedings (1)

Ethics of Early Clinical Trials of Bio-Artificial Organs

Author(s): Bunnik, E.M., de Jongh, D. and Massey, E.
Published in: Transplant International, 35, 2022, Page(s) 10621, ISSN 0934-0874
Publisher: Frontiers Publishing Partnerships
DOI: 10.3389/ti.2022.10621