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Indo-European Consortium for Next Generation Influenza Vaccine Innovation

Project description

Next-generation influenza vaccines

The strategic goals of the EU-funded INCENTIVE project are to advance knowledge of the underlying mechanisms of poor responsiveness to influenza vaccines (IVs) and to develop two next-generation universal IVs. This is a partnership between Indian, European and US groups that address the global health and economic challenge posed by influenza infections. The objectives include: performing comprehensive profiling of responders and non-responders to licensed IVs in infants, children, adults and elderly in phase IV trials in Europe and India to identify the mechanisms of vaccine responsiveness; advancing the development of two next-generation vaccines by providing a proof-of-concept for vaccine efficacy in non-human primates for an antigen presenting cell-targeted nucleic acid vaccine and developing a computationally-optimized vaccine up to phase II clinical trials and vaccine efficacy in a controlled human challenge; identifying predictive biomarkers of responsiveness to vaccination for new diagnostics; implementing technology transfer; and performing a health systems and investment analysis.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2019-Single-Stage-RTD

Coordinator

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Net EU contribution
€ 2 537 797,50
Address
Inhoffenstrasse 7
38124 Braunschweig
Germany

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Region
Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (20)

PUBLIC HEALTH FOUNDATION OF INDIA
India
Net EU contribution
€ 0,00
Address
Unit 431a, 4th Floor, Rectangle-1 Building Plot D-4, District Centre Saket
110017 New Delhi

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Activity type
Research Organisations
Non-EU contribution
€ 998 912,00
TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE
India
Net EU contribution
€ 0,00
Address
Ncr Biotech Science Cluster 3rd Milestone Haryana
121001 Faridabad

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Activity type
Research Organisations
Non-EU contribution
€ 2 541 318,00
UNIVERSITE LIBRE DE BRUXELLES
Belgium
Net EU contribution
€ 614 963,75
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITETET I BERGEN
Norway
Net EU contribution
€ 492 296,25
Address
Museplassen 1
5020 Bergen

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Region
Norge Vestlandet Vestland
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 1 698,75
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

HELSE BERGEN HF
Norway
Net EU contribution
€ 75 000,00
Address
Jonas Lies Vei 65
5021 Bergen

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Region
Norge Vestlandet Vestland
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITETET I OSLO
Norway
Net EU contribution
€ 307 086,25
Address
Problemveien 5-7
0313 Oslo

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Region
Norge Oslo og Viken Oslo
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITEIT ANTWERPEN
Belgium
Net EU contribution
€ 919 943,75
Address
Prinsstraat 13
2000 Antwerpen

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Region
Vlaams Gewest Prov. Antwerpen Arr. Antwerpen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 262 691,25
Address
Albinusdreef 2
2333 ZA Leiden

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Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

STICHTING CENTRE FOR HUMAN DRUG RESEARCH
Netherlands
Net EU contribution
€ 741 093,75
Address
Zernikedreef 8
2333 CL Leiden

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INSTITUT PASTEUR
France
Net EU contribution
€ 441 260,00
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ASA SPEZIALENZYME GMBH
Germany
Net EU contribution
€ 387 750,00
Address
Am Exer 19 C
38302 Wolfenbuttel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Niedersachsen Braunschweig Wolfenbüttel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
Net EU contribution
€ 383 670,00
Address
C Rossello 132 Planta 05
08036 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE
France
Net EU contribution
€ 531 858,75
Address
40 Avenue Tony Garnier
69007 Lyon

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Region
Auvergne-Rhône-Alpes Rhône-Alpes Rhône
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UGA RESEARCH FOUNDATION INC NON PROFIT CORP
United States
Net EU contribution
€ 586 990,00
Address
150d Paul D. Coverdell Center 500 Dw Brooks Drive
30602-7411 Athens

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Activity type
Research Organisations
Non-EU contribution
€ 0,00
STICHTING HUMAN VACCINES PROJECT EUROPE
Netherlands
Net EU contribution
€ 794 312,50
Address
Brakersweg 53
1901 XX Castricum

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Region
West-Nederland Noord-Holland IJmond
Activity type
Other
Non-EU contribution
€ 0,00
EUROVACC FOUNDATION
Switzerland
Net EU contribution
€ 136 875,00
Address
Place Saint-francois 1 Etude Kellerhals Carrard
1003 Lausanne

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Other
Non-EU contribution
€ 0,00
HUMAN VACCINES PROJECT, INC
United States
Net EU contribution
€ 760 705,00
Non-EU contribution
€ 0,00
INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IITM)
India
Net EU contribution
€ 0,00
Address
Centre For Industrial Consultancy And Sponsored Research Indian Institute If Technology Madras
600036 Chennai

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 889 378,00
SETH G S M COLLEGE AND K E M HOSPITAL DIAMOND JUBILEE SOCIETY
India
Net EU contribution
€ 0,00
Address
Acharya Donde Marg Parel
400012 Mumbai

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Activity type
Research Organisations
Non-EU contribution
€ 1 122 615,00
NATIONAL INSTITUTE OF IMMUNOLOGY SOCIETY
India
Net EU contribution
€ 0,00
Non-EU contribution
€ 4 437 777,00