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Indo-European Consortium for Next Generation Influenza Vaccine Innovation

Project description

Next-generation influenza vaccines

The strategic goals of the EU-funded INCENTIVE project are to advance knowledge of the underlying mechanisms of poor responsiveness to influenza vaccines (IVs) and to develop two next-generation universal IVs. This is a partnership between Indian, European and US groups that address the global health and economic challenge posed by influenza infections. The objectives include: performing comprehensive profiling of responders and non-responders to licensed IVs in infants, children, adults and elderly in phase IV trials in Europe and India to identify the mechanisms of vaccine responsiveness; advancing the development of two next-generation vaccines by providing a proof-of-concept for vaccine efficacy in non-human primates for an antigen presenting cell-targeted nucleic acid vaccine and developing a computationally-optimized vaccine up to phase II clinical trials and vaccine efficacy in a controlled human challenge; identifying predictive biomarkers of responsiveness to vaccination for new diagnostics; implementing technology transfer; and performing a health systems and investment analysis.

Field of science

  • /natural sciences/biological sciences/biochemistry/biomolecules/nucleic acid
  • /medical and health sciences/health sciences/infectious disease/RNA virus/influenza

Call for proposal

H2020-SC1-2019-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Address
Inhoffenstrasse 7
38124 Braunschweig
Germany
Activity type
Research Organisations
EU contribution
€ 2 537 797,50

Participants (18)

PUBLIC HEALTH FOUNDATION OF INDIA
India
EU contribution
€ 0
Address
Isid Campus, 4Th Institutional Area, Vasant Kunj
110070 New Delhi
Activity type
Research Organisations
TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE
India
EU contribution
€ 0
Address
Ncr Biotech Science Cluster 3Rd Milestone Haryana
121001 Faridabad
Activity type
Research Organisations
UNIVERSITE LIBRE DE BRUXELLES
Belgium
EU contribution
€ 614 963,75
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles
Activity type
Higher or Secondary Education Establishments
UNIVERSITETET I BERGEN
Norway
EU contribution
€ 567 296,25
Address
Museplassen 1
5020 Bergen
Activity type
Higher or Secondary Education Establishments
UNIVERSITETET I OSLO
Norway
EU contribution
€ 307 086,25
Address
Problemveien 5-7
0313 Oslo
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT ANTWERPEN
Belgium
EU contribution
€ 919 943,75
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 1 003 785
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
INSTITUT PASTEUR
France
EU contribution
€ 441 260
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Activity type
Research Organisations
ASA SPEZIALENZYME GMBH
Germany
EU contribution
€ 387 750
Address
Am Exer 19 C
38302 Wolfenbuttel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
EU contribution
€ 383 670
Address
C Rossello 132 Planta 05
08036 Barcelona
Activity type
Research Organisations
BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE
France
EU contribution
€ 531 858,75
Address
40 Avenue Tony Garnier
69007 Lyon
Activity type
Research Organisations
UGA RESEARCH FOUNDATION INC NON PROFIT CORP
United States
EU contribution
€ 586 990
Address
150D Paul D. Coverdell Center 500 Dw Brooks Drive
30602-7411 Athens
Activity type
Research Organisations
STICHTING HUMAN VACCINES PROJECT EUROPE
Netherlands
EU contribution
€ 794 312,50
Address
Brakersweg 53
1901 XX Castricum
Activity type
Other
EUROVACC FOUNDATION
Switzerland
EU contribution
€ 136 875
Address
Place Saint-francois 1 Etude Kellerhals Carrard
1003 Lausanne
Activity type
Other
HUMAN VACCINES PROJECT, INC
United States
EU contribution
€ 760 705
Address
251 Little Falls Drive
19808 Wilmington New Castle
Activity type
Other
INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IITM)
India
EU contribution
€ 0
Address
Centre For Industrial Consultancy And Sponsored Research Indian Institute If Technology Madras
600036 Chennai
Activity type
Higher or Secondary Education Establishments
SETH G S M COLLEGE AND K E M HOSPITAL DIAMOND JUBILEE SOCIETY
India
EU contribution
€ 0
Address
Acharya Donde Marg Parel
400012 Mumbai
Activity type
Research Organisations
NATIONAL INSTITUTE OF IMMUNOLOGY SOCIETY
India
EU contribution
€ 0
Address
Aruna Asaf Ali Marg
110067 New Delhi
Activity type
Research Organisations