Project description
Microalgae ramp up production of one of the most powerful antioxidants
Astaxanthin belongs to the carotenoid class, a group of common pigments found in red and yellow plants as well as algae and bacteria. It is also one of the most powerful antioxidants around. Antioxidants are literally compounds that are 'against oxidation'. More specifically, they protect cells from free radicals, unstable molecules produced as a result of oxidation reactions associated with normal metabolic processes. Antioxidants are important additives to products we eat or put on our skin because they may help protect us against cancer, heart disease, stroke and various conditions related to the ageing process. Microalgae have become the most promising sources for the industrial production of astaxanthin, and the EU-funded ASTEASY project is exploiting that potential, bringing to market its process to significantly increase astaxanthin yield, decrease production time and cut costs.
Objective
Astaxanthin is a carotenoid with a high commercial value. Its high anti-oxidant activity makes Astaxanthin being used as a food/feed supplements, in cosmetics, and in nutraceutics. Microalgae are the main primary sources of Astaxanthin, being produced at industrial level mainly by cultivation of the green alga Haematococcus pluvialis with high costs for cultivation and extraction, hindering its market.
In the ERC-StG-SOLENALGAE project the investigation of the role of carotenoids in photoprotection in microalgae led to the development of an innovative platform for Astaxanthin production. Strains with high Astaxanthin accumulation were indeed obtained by metabolic engineering in the green alga Chlamydomonas reinhardtii (usually not accumulating Astaxanthin), producing up to 4 mg/L per day in non-optimized growth conditions. Astaxanthin production by bkt15 strain revealed unique advantages compared to other source of natural Astaxanthin: production of Astaxanthin in continuous, in a single cultivation step; high bio-accessibility for animal or human assimilation; easier extraction of astaxanthin even without costly cell pre-treatments; lower extraction costs and no contamination from oxidant molecules as chlorophylls during extraction process. These advantages lead to a potential increase in pure Astaxanthin productivity up to 16-fold higher than the current methods.
ASTEASY PoC aims to the technological development of the new system, by optimizing the cultivation conditions and extraction processes of Astaxanthin from the bkt15 strain and validating the performances in 60 litres demonstrator units. We will also identify and protect the IP generated and analyse the certification needed for commercialization. A business plan will be drafted as a result of interactions with stakeholders and literature analysis, to define market size and trends, and consolidate the business model (Astaxanthin production through a dedicated spin-off vs licensing to Astaxanthin producers).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology industrial biotechnology metabolic engineering
- natural sciences biological sciences microbiology phycology
- social sciences economics and business business and management business models
- social sciences economics and business economics production economics productivity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC-LS - ERC Proof of Concept Lump Sum Pilot
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2019-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
37129 Verona
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.