Stratification of Obesity Phenotypes to Optimize Future Therapy

Resultado final

Dataset profiles handbook
Needs and challenges communication package

Publicaciones

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood

Autores: Gareth Hawkes; Robin N. Beaumont; Jessica Tyrrell; Grace M. Power; Andrew Wood; Markku Laakso; Lilian Fernandes Silva; Michael Boehnke; Xianyong Yin; Tom G. Richardson; George Davey Smith; Timothy M. Frayling
Publicado en: Diabetologia, 2023, ISSN 1949-2448
Editor: Springer link
DOI: 10.1007/s00125-023-05923-6

Is COVID-19 to Blame? Trends of Incidence and Sex Ratio in Youth-Onset Type 2 Diabetes in Germany

Autores: Christian Denzer; Christian Denzer; Daniela Klose; Antje Korner; Thomas Reinehr; Christina Baechle; Carmen Schroder; Susanna Wiegand; Reinhard W. Holl; Nicole Prinz
Publicado en: Diabetes care, 2023, ISSN 0012-1797
Editor: American Diabetes Association
DOI: 10.2337/dc22-2257

Cardiovascular health, genetic predisposition, and lifetime risk of type 2 diabetes

Autores: Kan Wang; Maryam Kavousi; Trudy Voortman; M. Arfan Ikram; Mohsen Ghanbari; Fariba Ahmadizar;
Publicado en: European Journal of Preventive Cardiology, 2021, ISSN 2047-4873
Editor: SAGE Publications Ltd
DOI: 10.1093/eurjpc/zwab141

A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Autores: Daniel E. Coral; Juan Fernandez-Tajes; Neli Tsereteli; Hugo Pomares-Millan; Hugo Fitipaldi; Pascal M. Mutie; Naeimeh Atabaki-Pasdar; Sebastian Kalamajski; Alaitz Poveda; Tyne W. Miller-Fleming; Xue Zhong; Giuseppe N. Giordano; Ewan R. Pearson; Nancy J. Cox; Paul W. Franks
Publicado en: Nature Metabolism, 2023, ISSN 2522-5812
Editor: Nature Metabolism
DOI: 10.1038/s42255-022-00731-5

Comparison of cardiovascular risk factors between children and adolescents with classes III and IV obesity: findings from the APV cohort

Autores: Thomas Reinehr, Sascha R. Tittel, Rolf Holle, Susanna Wiegand, Ines Gellhaus, Johannes Hebebrand, Susanne Greber-Platzer, Christian Denzer, Sabine Linke, Wieland Kiess, Reinhard W. Holl
Publicado en: International Journal of Obesity, Edición 45/5, 2021, Página(s) 1061-1073, ISSN 0307-0565
Editor: Nature Publishing Group
DOI: 10.1038/s41366-021-00773-x

“You Are Always at War With Yourself” The Perceptions and Beliefs of People With Obesity Regarding Obesity as a Disease

Autores: Andrew Grannell; Carel W. le Roux; Deirdre McGillicuddy;
Publicado en: Qualitative Health Research, 2021, ISSN 1049-7323
Editor: SAGE Publications
DOI: 10.1177/10497323211040767

The lived experience of people with obesity: study protocol for a systematic review and synthesis of qualitative studies

Autores: Emma Farrell, Marta Bustillo, Carel W. le Roux, Joe Nadglowski, Eva Hollmann & Deirdre McGillicuddy
Publicado en: Systematic Reviews, 2021, ISSN 2046-4053
Editor: BioMed Central
DOI: 10.1186/s13643-021-01706-5

Altered Insulin Clearance after Gastric Bypass and Sleeve Gastrectomy in the Fasting and Prandial Conditions

Autores: Marzieh Salehi, Ralph DeFronzo, and Amalia Gastaldelli
Publicado en: Molecular Sciences, 2022, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23147667

Exposome-wide ranking of modifiable risk factors for cardiometabolic disease traits

Autores: Alaitz Poveda; Hugo Pomares-Millan; Yan Chen; Azra Kurbasic; Chirag J. Patel; Frida Renström; Göran Hallmans,; Ingegerd Johansson; Paul W. Franks
Publicado en: Sci Rep, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-08050-1

Not All Type-2-Diabetes Patients Increase Body Mass Index After Initiating Insulin: Results of Latent Class Analysis from the DPV Registry

Autores: Nicole Prinz; Anke Schwandt; Bernadette Borgert; Bettina Hartmann; Hans-Peter Kempe; Julia K. Mader; Sigrund Merger; Rosmarie Weber-Lauffer; Frank-Jürgen Wosch; Reinhard W. Holl;
Publicado en: Diabetes Technology & Therapeutics, 2021, ISSN 1520-9156
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/dia.2021.0144

The lived experience of patients with obesity: A systematic review and qualitative synthesis

Autores: Emma Farrell, Eva Hollmann, Carel W. le Roux, Marta Bustillo, Joe Nadglowski, Deirdre McGillicuddy
Publicado en: Obesity Reviews, 2021, ISSN 1467-7881
Editor: Blackwell Publishing Inc.
DOI: 10.1111/obr.13334

Disease heterogeneity of adult diabetes based on routine clinical variables at diagnosis: Results from the German/Austrian Diabetes Follow-up Registry

Autores: Julia M. Grimsmann; Sascha R. Tittel; Peter Bramlage; Benjamin Mayer; Andreas Fritsche; Jochen Seufert; Markus Laimer; Stefan Zimny; Sebastian M. Meyhoefer; Michael Hummel; Reinhard W. Holl
Publicado en: Diabetes, Obesity and Metabolism, 2022, ISSN 1463-1326
Editor: Diabetes, Obesity and Metabolism
DOI: 10.1111/dom.14812

Special diet in type 1 diabetes: do gender and BMI-SDS differ?

Autores: Alena Gerlinde Thiele; Nicole Prinz; Monika Flury; Melanie Hess; Daniela Klose; Thomas Meissner; Klemens Raile; Klemens Raile; Sabine Wenzel; Sascha Tittel; Thomas Kapellen; Reinhard Holl
Publicado en: Child and Adolescent Obesity, 2021, ISSN 2227-9067
Editor: Taylor & Francis
DOI: 10.1080/2574254x.2021.2002061

Plasma circulating microRNAs associated with obesity, body fat distribution, and fat mass: the Rotterdam Study

Autores: Yasir J. Abozaid; Xiaofang Zhang; Michelle M. J. Mens; Fariba Ahmadizar; Marlou Limpens; M. Arfan Ikram; Fernando Rivadeneira; Trudy Voortman; Maryam Kavousi; Mohsen Ghanbari
Publicado en: International Journal of Obesity, 2022, ISSN 1476-4687
Editor: Nature
DOI: 10.1038/s41366-022-01227-8

Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

Autores: Giulia Angelini; Lidia Castagneto-Gissey; Serenella Salinari; Alessandro Bertuzzi; Danila Anello; Meenakshi Pradhan; Marlen Zschätzsch; Paul Ritter; CarelW. Le Roux; Francesco Rubino; Nicola Basso; Giovanni Casella; Stefan R. Bornstein; Valentina Tremaroli; Geltrude Mingrone
Publicado en: Nature Communications, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-35310-5

Obesity in people living with type 1 diabetes

Autores: Bart Van der Schueren Darcy Ellis Raquel NFaradji Eeba Al-Ozairi Jonathan Rosen Chantal Mathieu
Publicado en: The Lancet Diabetes & Endocrinology, 2021, ISSN 2213-8587
Editor: Elsevier BV
DOI: 10.1016/s2213-8587(21)00246-1

At home and at risk: The experiences of Irish adults living with obesity during the COVID-19 pandemic

Autores: Emma Farrell; Eva Hollmann; Carel Le Roux; Joe Nadglowski; Deirdre McGillicuddy
Publicado en: EClinicalMedicine, 2022, ISSN 2589-5370
Editor: Elsevier
DOI: 10.1016/j.eclinm.2022.101568

“I am terrified of something happening to me” The lived experience of people with obesity during the COVID ‐19 pandemic

Autores: Andrew Grannell, Carel W. Roux, Deirdre McGillicuddy
Publicado en: Clinical Obesity, Edición 10/6, 2020, ISSN 1758-8103
Editor: Clinical Obesity
DOI: 10.1111/cob.12406

Association between arterial stiffness/remodeling and new-onset type 2 diabetes mellitus in general population

Autores: Fariba Ahmadizar; Kan Wang; Maurits Roos; Maxime Bos; Francesco Mattace- Raso; Maryam Kavousi
Publicado en: Diabetes Research and Clinical Practice, 2023, ISSN 0168-8227
Editor: Elsevier BV
DOI: 10.1016/j.diabres.2023.110237

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