Project description
A novel treatment may help some patients avoid open heart surgery
Blood flows from your heart to the rest of your body through the aorta. With age and other risk factors, the aorta loses elasticity. If the inner layer of the aortic wall ruptures, blood flow rushing through the tear can cause the inner and middle layers to detach (dissect). This medical emergency can be lethal if it leads to rupture of the outer layer. Currently, aortic dissection is treated with surgery to remove the damaged tissue, stop blood flowing into the aortic wall, and reconstruct the aorta with a rigid stent. AORTYX has developed a flexible patch that can be inserted without invasive surgery to promote healing. With EU funding, the team is getting ready for pre-clinical trials.
Objective
Aortic Dissection is a major disease affecting 3-12/100.000 patients/year. Global mortality rates are upto 40% and yet symptoms are hard to diagnose, with today´s treatments not specifically designed for the condition resulting in a high tendency to fail.
Aortyx wants to change that. We have developed a Vascular graft, a “patch” that is inserted via a minimally invasive procedure. It adheres to the fissure, stops the blood flowing between the layers, then promotes natural repair. Complicated, life threatening, Open Heart Surgery is avoided, as well as post-operation failures as we replace today´s rigid ‘stents’ with our highly flexible, almost natural patch.
We have successfully proved the product operation in early pre-clinical trials, have a patent application in progress and the backing of several expert vascular surgeons.
For this phase 1 project we wish to finalise our pre-clinical trial planning, as well as our business planning to create a new vascular grafting company with predicted accumulated incomes of 13.78M€ and 13 employees by 2025.
Fields of science
Programme(s)
Funding Scheme
SME-1 - SME instrument phase 1Coordinator
08329 Teia
Spain
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.