Project description
A novel treatment may help some patients avoid open heart surgery
Blood flows from your heart to the rest of your body through the aorta. With age and other risk factors, the aorta loses elasticity. If the inner layer of the aortic wall ruptures, blood flow rushing through the tear can cause the inner and middle layers to detach (dissect). This medical emergency can be lethal if it leads to rupture of the outer layer. Currently, aortic dissection is treated with surgery to remove the damaged tissue, stop blood flowing into the aortic wall, and reconstruct the aorta with a rigid stent. AORTYX has developed a flexible patch that can be inserted without invasive surgery to promote healing. With EU funding, the team is getting ready for pre-clinical trials.
Objective
Aortic Dissection is a major disease affecting 3-12/100.000 patients/year. Global mortality rates are upto 40% and yet symptoms are hard to diagnose, with today´s treatments not specifically designed for the condition resulting in a high tendency to fail.
Aortyx wants to change that. We have developed a Vascular graft, a “patch” that is inserted via a minimally invasive procedure. It adheres to the fissure, stops the blood flowing between the layers, then promotes natural repair. Complicated, life threatening, Open Heart Surgery is avoided, as well as post-operation failures as we replace today´s rigid ‘stents’ with our highly flexible, almost natural patch.
We have successfully proved the product operation in early pre-clinical trials, have a patent application in progress and the backing of several expert vascular surgeons.
For this phase 1 project we wish to finalise our pre-clinical trial planning, as well as our business planning to create a new vascular grafting company with predicted accumulated incomes of 13.78M€ and 13 employees by 2025.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences clinical medicine surgery
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
08329 Teia
Spain
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.