Epileptic Seizure Prediction System (ESPS) - Predicting and preventing epileptic seizures based on respiratory biofeedback & machine learning.

Informations projet

ESPS

N° de convention de subvention: 876106

DOI

10.3030/876106

Projet clôturé

Date de signature de la CE 21 Juillet 2019

Date de début 1 Juillet 2019

Date de fin 31 Decembre 2019

Financé au titre de

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Coût total

€ 71 429,00

Contribution de l’UE

€ 50 000,00

Coordonné par

IBREVE LIMITED
Ireland

Periodic Reporting for period 1 - ESPS (Epileptic Seizure Prediction System (ESPS) - Predicting and preventing epileptic seizures based on respiratory biofeedback & machine learning.)

Période du rapport: 2019-07-01 au 2019-12-31

Résumé du contexte et des objectifs généraux du projet

Epilepsy is one of the most common nervous system disorders and affects more than 50M people worldwide. Currently there is no cure for epilepsy. Although antiepileptic drugs can help, one third of all patients do not respond to any pharmacological intervention. This staggering number has not changed in decades, despite over 14 new therapies entering the market.
Seizures that lasts for more than a brief period of time are a medical emergency and can lead to death. Each year, more than 1 out of 1,000 people with epilepsy die from sudden unexpected death in epilepsy (SUDEP). If seizures are uncontrolled, the risk of SUDEP increases to more than 1 out of 150.
Importance for Society: Approximately 8-10% of people will experience an epileptic seizure during their lifetime. The majority of new-onset cases occur in elderly and children. The unpredictable nature of seizures causes the largest burden for patients as it literally disrupts their lives. Patients with several seizures a week are hesitant to leave the house & find it hard to obtain employment.
Main objective of this feasibility study was the development of a comprehensive business plan to evaluate the opportunities & risks of introducing ESPS into the homecare market. The results of the feasibility study manifest the project’s technological, practical as well as economical feasibility.

Travail effectué depuis le début du projet jusqu’à la fin de la période considérée dans le rapport et principaux résultats atteints jusqu’à présent

The performed work & results follow the Healthcare Innovation Cycle methodology & were structured around the 4 development pillars - Business, Technology, Clinical and Regulatory. A comprehensive business plan has been developed, based on conducted interviews, performed re-risking experiments & advice from experts in the field. The results of the feasibility study manifest the project’s technological, practical as well as economical feasibility of its breakthrough concept.

Progrès au-delà de l’état des connaissances et impact potentiel prévu (y compris l’impact socio-économique et les conséquences sociétales plus larges du projet jusqu’à présent)

The unpredictable nature of seizures has the largest impact on patient’s quality of life. Patients with several seizures a week are hesitant to leave the house & find it hard to obtain employment. Reliably predicting seizures enables a more independent life, allows participation in social life outside the homes and reduces healthcare costs caused by injuries. ESPS’s new patent-pending wearable technology analyzes respiratory patterns in real-time, enabling market applications for seizure monitoring, respiratory treatment & stress management.

The wearable helping with stress, anxiety & chronic disease management