Project description
Embolisation treatment device for arthritic knee pain
Osteoarthritis (OA) is a long-term chronic disease characterised by the deterioration of cartilage in joints, which results in bones rubbing together and creating stiffness, pain, and impaired movement. OA is the single most common cause of disability in older adults, and prevalence is increasing due to population ageing. It is also responsible for millions of steroid and non-steroid based knee injections globally each year. The EU-funded ADDEGE project is developing a new treatment paradigm for OA. This device will allow interventional radiologists to reach deep into the anatomy and safely deliver targeted embolisation treatment to OA patients. It will operate and treat areas that are significantly smaller than those currently treated.
Objective
Chronic knee pain from osteoarthritis (OA) is prevalent in 12% of the global population over the age of 60 (Yuji Okuno,
Amine Korchi, Takuma Shinjo, Shojiro Kato, Takao Kaneko, 2017). OA results in a loss of mobility and debilitating pain in
those effected. It can ultimately lead to invasive knee replacement or reconstruction surgery. OA is responsible for more than
6 million steroid and non-steroid based knee injections globally each year. It is among the top three reasons, globally, for
both opioid and nonsteroidal anti-inflammatory drug prescriptions.
Given the well documented economic benefit that comes with restored mobility in patients, the negative side effects of
current drug treatments (addition for opioids and gastrointestinal complications for NSAIDs), the expense and recovery time
associated with surgery, and the high ongoing cost of drug therapy, a new treatment paradigm for osteoarthritis is certainly
needed.
The end product is a device will allow Interventional Radiologists to reach deep into the anatomy and safely deliver targeted
embolisation treatment to this patient population. It will operate and treat in arteries that are significantly smaller than those
currently treated.
The treatment has the potential to generate a €2Bn saving from the global healthcare spend and delivery meaningful long
term pain relief for up to 90% of those treated.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine anatomy and morphology
- medical and health sciences clinical medicine rheumatology
- medical and health sciences clinical medicine surgery
- engineering and technology materials engineering coating and films
- natural sciences chemical sciences organic chemistry amines
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.3. - PRIORITY 'Societal challenges
See all projects funded under this programme -
H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
H91XW6Y Galway
Ireland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.