Disentangling metaphase chromosome organisation one chromosome at a time

Project Information

MONOCHROME

Grant agreement ID: 883240

DOI

10.3030/883240

EC signature date 13 May 2020

Start date 1 January 2021

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 997 284,00

EU contribution

€ 1 997 284,00

Coordinated by

STICHTING VU
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Force generation and resistance in human mitosis

Author(s): Colleen C. Caldwell, Tinka V. M. Clement, Gijs J. L. Wuite
Published in: Biophysical Reviews, Issue 16, 2024, Page(s) 551-562, ISSN 1867-2450
Publisher: Springer Verlag
DOI: 10.1007/s12551-024-01235-0

Mapping fast DNA polymerase exchange during replication

Author(s): Longfu Xu, Matthew T. J. Halma, Gijs J. L. Wuite
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49612-3

The Mechanics of Mitotic Chromosomes.

Author(s): Tianlong Man; Hannes Witt; Erwin J.G. Peterman; Gijs J.L. Wuite
Published in: Q Rev Biophys, Issue 4, 2021, ISSN 0033-5835
Publisher: Cambridge University Press
DOI: 10.1017/s0033583521000081

DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

Author(s): Longfu Xu, Shikai Jin, Mia Urem, Seung-Joo Lee, Meindert H. Lamers, Xun Chen, Peter Wolynes, Gijs J. L. Wuite
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/2025.03.07.642097

PICH acts as a force-dependent nucleosome remodeler

Author(s): Dian Spakman; Tinka V. M. Clement; Andreas S. Biebricher; Graeme A. King; Manika I. Singh; Ian D. Hickson; Erwin J. G. Peterman; Gijs J. L. Wuite
Published in: nature communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-35040-8

CENP-B-mediated DNA loops regulate activity and stability of human centromeres

Author(s): Florian Chardon 4 Aleksandre Japaridze 4; Hannes Witt; Leonid Velikovsky Camellia Chakraborty Therese Wilhelm Marie Dumont Wayne Yang Carlos Kikuti Stephane Gangnard Anne-Sophie Mace Gijs Wuite Cees Dekker Daniele Fachinetti 5
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.02.032

Ion-mediated condensation controls the mechanics of mitotic chromosomes

Author(s): Hannes Witt, Janni Harju, Emma M. J. Chameau, Charlotte M. A. Bruinsma, Tinka V. M. Clement, Christian F. Nielsen, Ian D. Hickson, Erwin J. G. Peterman, Chase P. Broedersz, Gijs J. L. Wuite
Published in: Nature Materials, Issue 23, 2024, Page(s) 1556-1562, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-024-01975-0

Viscoelastic phenotyping of red blood cells

Author(s): Marta Gironella-Torrent, Giulia Bergamaschi, Raya Sorkin, Gijs J.L. Wuite, Felix Ritort
Published in: Biophysical Journal, Issue 123, 2025, Page(s) 770-781, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2024.01.019

Nonlinear mechanics of human mitotic chromosomes

Author(s): Anna E. C. Meijering, Kata Sarlós, Christian F. Nielsen, Hannes Witt, Janni Harju, Emma Kerklingh, Guus H. Haasnoot, Anna H. Bizard, Iddo Heller, Chase P. Broedersz, Ying Liu, Erwin J. G. Peterman, Ian D. Hickson & Gijs J. L. Wuite
Published in: Nature, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04666-5