Tissue repair functions of MAIT cells: integrating thymic pre-commitment and peripheral signals

Project Information

MAIT

Grant agreement ID: 885435

DOI

10.3030/885435

Project closed

EC signature date 18 May 2020

Start date 1 October 2020

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 500,00

EU contribution

€ 2 499 500,00

Coordinated by

INSTITUT CURIE
France

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

A data management plan corresponds to the expected deliverable in the frame of the Open Research Data Pilot subscription.

Publications

Peer reviewed articles (10)

Fighting Liver Metastasis by Activating MAIT Cells

Author(s): Lantz O
Published in: Cancer Immunol Res, 2021, ISSN 0000-0000
Publisher: Cancer Immunol Res
DOI: 10.1158/2326-6066.cir-21-0502

"Introduction to the special issue on ""unconventional T cells"

Author(s): Legoux F, Lantz O.
Published in: Semin Immunol., 2022, ISSN 0000-0000
Publisher: Semin Immunol
DOI: 10.1016/j.smim.2022.101666

Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing

Author(s): Du Halgouet, A. Darbois, M. Alkobtawi, M. Mestdagh, A. Alphonse, V. Premel, T. Yvorra, L. Colombeau, R. Rodriguez, D. Zaiss, Y. El Morr, H. Bugaut, F. Legoux, L. Perrin, S. Aractingi, R. Golub, O. Lantz*, M. Salou*.
Published in: Immunity, 2022, ISSN 0000-0000
Publisher: Immunity
DOI: 10.1016/j.immuni.2022.12.004

Chronic stress physically spares but functionally impairs innate-like invariant T cells

Author(s): Rudak, PT, Choi, J, Parkins, KM, Summers, KL, Jackson, DN, Foster, PJ, Skaro, AI, Leslie, K, McAlister, VC, Kuchroo, VK, Inoue, W, Lantz, O, Haeryfar, SMM.
Published in: Cell Reports, 2021, ISSN 0000-0000
Publisher: Cell Reports
DOI: 10.1016/j.celrep.2021.108979

MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis

Author(s): Yara El Morr, Mariela Fürstenheim, Martin Mestdagh, Katarzyna Franciszkiewicz, Marion Salou, Claire Morvan, Thierry Dupré, Alexey Vorobev, Bakhos Jneid, Virginie Premel, Aurélie Darbois, Laetitia Perrin, Stanislas Mondot, Ludovic Colombeau, Hélène Bugaut, Anastasia du Halgouet, Sophie Richon, Emanuele Procopio, Mathieu Maurin, Catherine Philippe, Raphael Rodriguez, Olivier Lantz, François Le
Published in: Science Immunology, Issue 9, 2024, ISSN 2470-9468
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciimmunol.adi8954

Synthesis, biological evaluation and molecular modelling of new potent clickable analogues of 5-OP-RU for their use as chemical probes for the study of MAIT cell biology

Author(s): Yvorra T, Steinmetz A, Retailleau P, Lantz O, Schmidt F
Published in: Eur J Med Chem, 2021, ISSN 0000-0000
Publisher: Eur J Med Chem
DOI: 10.1016/j.ejmech.2020.113066

A conserved transcriptional program for MAIT cells across mammalian evolution

Author(s): Hélène Bugaut, Yara El Morr, Martin Mestdagh, Aurélie Darbois, Rafael A. Paiva, Marion Salou, Laetitia Perrin, Mariela Fürstenheim, Anastasia du Halgouet, Linda Bilonda-Mutala, Anne-Laure Le Gac, Manon Arnaud, Ahmed El Marjou, Coralie Guerin, Atitheb Chaiyasitdhi, Julie Piquet, David M. Smadja, Agata Cieslak, Bernhard Ryffel, Valdone Maciulyte, James M.A. Turner, Karine Bernardeau, Xavier Mont
Published in: Journal of Experimental Medicine, Issue 221, 2023, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20231487

Innate-like T cell subset commitment in the murine thymus is independent of TCR characteristics and occurs during proliferation

Author(s): Vadim K. Karnaukhov, Anne-Laure Le Gac, Linda Bilonda Mutala, Aurélie Darbois, Laetitia Perrin, Francois Legoux, Aleksandra M. Walczak, Thierry Mora, Olivier Lantz
Published in: Proceedings of the National Academy of Sciences, Issue 121, 2024, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2311348121

Identification of T cell antigens in the 21st century, as difficult as ever

Author(s): Lantz O, Teyton L
Published in: Semin Immunol, 2022, ISSN 0000-0000
Publisher: Semin Immunol.
DOI: 10.1016/j.smim.2022.101659

gamma-delta, NKT and MAIT cells during evolution: redundancy or specialized functions?

Author(s): Christelle Harly*, Jacques Robert, Francois Legoux, Olivier Lantz
Published in: Journal of Immunology, 2022, ISSN 0000-0000
Publisher: Journal of Immunology
DOI: 10.4049/jimmunol.2200105