HEART FIne REgulation through mechanosensing in myosin filaments: merging theory and experiments into a multi-scale heart simulator

Información del proyecto

Heart Fi-Re

Identificador del acuerdo de subvención: 886232

DOI 10.3030/886232

Fecha de la firma de la CE 17 Marzo 2020

Fecha de inicio 1 Julio 2021

Fecha de finalización 29 Septiembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total € 276 498,24

Aportación de la UE € 276 498,24

Coordinado por

UNIVERSITA DEGLI STUDI DI PADOVA
Italy

Publicaciones

Peer reviewed articles (4)

Cytosolic Ca2+ gradients and mitochondrial Ca2+ uptake in resting muscle fibers: A model analysis

Autores: Marcucci Lorenzo, Michelucci Antonio, Reggiani Carlo
Publicado en: Biophysical Reports, 2023, ISSN 2667-0747
Editor: Biophysical Society
DOI: 10.1016/j.bpr.2023.100117

A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?

Autores: Reggiani, Carlo; Marcucci, Lorenzo
Publicado en: THE JOURNAL OF GENERAL PHYSIOLOGY, 2022, ISSN 0022-1295
Editor: Rockefeller University Press
DOI: 10.1085/jgp.202213167

Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism

Autores: Elisabetta Brunello, Lorenzo Marcucci, Malcolm Irving, Luca Fusi
Publicado en: Proceedings of the National Academy of Sciences of the United States of America, 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2302837120

Muscle Mechanics and Thick Filament Activation: An Emerging Two-Way Interaction for the Vertebrate Striated Muscle Fine Regulation

Autores: Lorenzo Marcucci
Publicado en: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076265