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Evaluating Dermal Metabolism and Uptake as Pathways of Human Exposure to Per- and PolyFluoroAlkyl Substances (PFAS) in Cosmetics (FluoroCosm)

Project description

An in vitro 3D skin model for assessing cosmetic chemicals

Per- and polyfluoroalkyl substances (PFAS) are man-made chemicals encountered at high levels in many products including cosmetics. Scientists of the EU-funded FluoroCosm project wish to determine the toxicity of these compounds following contact with the human skin. For this purpose, they will employ innovative 3D human tissue culture techniques to study dermal absorption and metabolism of PFAS. This skin equivalent approach has the potential to serve as an advanced model for investigating the implication of the skin in PFAS pharmacokinetics. More importantly, it will offer accurate risk assessment of these chemicals alongside information on their effect on human health.

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Net EU contribution
€ 224 933,76
Address
Edgbaston
B15 2TT Birmingham
United Kingdom

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Region
West Midlands (England) West Midlands Birmingham
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00