A skin substitute optimised using mechanobiological simulation to restore weight-bearing function

Project description

Tissue-engineered skin for the foot sole

Tissue-engineered skin is used to treat chronic wounds that affect nearly four million people in Europe alone. However, there is currently no effective solution for the weight-bearing function of foot skin, and with the increasing incidence of diabetic foot ulcers, there is a pressing need for new reconstructive therapies. The EU-funded SKIN-REGEN-MECH project will investigate in vitro how changes in the mechanical environment of skin explants affect biological responses. Using this information, scientists will generate a computational model of skin mechano-regulation for predicting the optimal mechanical and morphological properties for skin regeneration. The project's results will improve the design of engineered skin and generate new substitutes for reconstructing the skin of the foot sole.

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

ROYAL COLLEGE OF SURGEONS IN IRELAND

Address

Saint Stephen's Green 123
2 Dublin
Ireland

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 196 590,72