From protein sequence to function – computational and experimental de-orphanization of uncharacterized enzymes in fungi

Project Information

fORPHAN

Grant agreement ID: 893122

DOI 10.3030/893122

Project closed

EC signature date 11 March 2020

Start date 1 November 2020

End date 20 February 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 187 572,48

EU contribution € 187 572,48

Coordinated by

RIJKSUNIVERSITEIT GRONINGEN
Netherlands

Publications

Peer reviewed articles (4)

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

Author(s): Barbara R Terlouw, Kai Blin, Jorge C Navarro-Muñoz, Nicole E Avalon, Marc G Chevrette, Susan Egbert, Sanghoon Lee, David Meijer, Michael J J Recchia, Zachary L Reitz, Jeffrey A van Santen, Nelly Selem-Mojica, Thomas Tørring, Liana Zaroubi, Mohammad Alanjary, Gajender Aleti, César Aguilar, Suhad A A Al-Salihi, Hannah E Augustijn, J Abraham Avelar-Rivas, Luis A Avitia-Domínguez, Francisco Barona
Published in: Nucleic Acids Research, Issue 51(D1), 2022, Page(s) D603–D610, ISSN 1362-4962
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac1049

Current State and Future Directions of Genetics and Genomics of Endophytic Fungi for Bioprospecting Efforts

Author(s): Sagita, Rosa Quax, Wim J Haslinger, Kristina
Published in: Frontiers in Bioengineering and Biotechnology, Issue vol. 9, 2021, Page(s) 649906, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2021.649906

Structural characterization and extended substrate scope analysis of two Mg2+-dependent O-methyltransferases from bacteria

Author(s): Sokolova, Nika; Zhang, Lili; Deravi, Sadaf; Oerlemans, Rick; Mathew, Groves R; Haslinger, Kristina
Published in: ChemBioChem, Issue 24(9), 2023, Page(s) e202300076, ISSN 1439-7633
Publisher: Wiley-VCH GmbH
DOI: 10.1101/2023.01.28.526015

Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli

Author(s): Iacovelli, Riccardo; Sokolova, Nika; Haslinger, Kristina
Published in: Biochemical Society Transactions, Issue 50(5), 2022, Page(s) 1315–1328, ISSN 0300-5127
Publisher: Portland Press, Ltd.
DOI: 10.1042/BST20220218

Conference proceedings (1)

Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids.

Author(s): Peng B, Zhang L, He S, Oerlemans R, Quax WJ, Groves MR, and Haslinger, K
Published in: 2022
Publisher: BioRxiv
DOI: 10.1101/2022.10.02.510496