Modeling the pharmacokinetics profiles of therapeutic peptides by chemoinformatics methods

Project description

Virtual screening of therapeutic peptides could break current barriers to widespread use

Over the last couple of decades, substantial technological progress has renewed scientists' interest in the promise of therapeutic peptides to improve the health and well-being of people around the globe. However, despite their potential application in numerous conditions and diseases, therapeutic peptides face important practical barriers related to low stability and short half-life. The EU-funded PeptiMOL project is developing mathematical models and computational tools in a Java-based chemoinformatic platform to help scientists virtually screen or design peptides based on desirable physicochemical characteristics and bioactivity. The project aims to introduce alternative routes of peptide administration, replacing the multiple injections per day currently required for many conditions.

Fields of science

• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs › antivirals
• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmacokinetics
• natural sciences › mathematics › applied mathematics › mathematical model
• natural sciences › biological sciences › neurobiology

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-SE - Society and Enterprise panel

Coordinator

MOLDRUG AI SYSTEMS SL

Address

Calle Olympia Arozena, 45
46018 Valencia
Spain

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU contribution

€ 160 932,48