Skip to main content

Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context.

Project description

Dissecting neuroinflammation in Parkinson's disease

Over one million people in Europe alone suffer from Parkinsonian disorders (PD), which lead to decreased motor activity. Accumulating evidence indicates that neuroinflammation is partly responsible for the observed PD pathology with IFNβ signalling playing an instrumental role in neuronal function. The EU-funded ParkIFNAR project aims to study the IFNβ pathway in PD, identify mutations in the IFNβ receptors (IFNARs) in PD patients and assess how these affect downstream signalling events. Collectively, the project's activities have the potential to identify pathway regulators that could be used to restore neuronal homeostasis and therefore serve as therapeutic targets in PD.

Call for proposal

See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF


Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 207 312