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Functional high-throughput analysis of the role of microRNAs in regulating Staphylococcus aureus infection

Project description

The role of microRNAs in Staphylococcus aureus infection

Staphylococcus aureus infections constitute a leading cause of morbidity and mortality in developed countries. The high prevalence of antibiotic-resistant S. aureus strains necessitates a better understanding of the factors that govern host–pathogen interaction and cause bacterial resistance. Emerging evidence indicates the implication of microRNAs in antibiotic resistance, in the interaction between the pathogen and the host or as a mechanism of immune evasion. With this in mind, scientists of the EU-funded miRs4Staph project will characterise host microRNAs implicated in the interaction of S. aureus with the host. Through various interdisciplinary and innovative strategies, the project will identify and validate microRNAs involved in S. aureus infection that could serve as targets for the design of future therapeutic interventions.

Coordinator

CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Net EU contribution
€ 147 815,04
Address
Universidade De Coimbra Largo Marques De Pombal
3004 517 Coimbra
Portugal

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Region
Continente Centro (PT) Região de Coimbra
Activity type
Research Organisations
Other funding
€ 0,00