Project description
The role of microRNAs in Staphylococcus aureus infection
Staphylococcus aureus infections constitute a leading cause of morbidity and mortality in developed countries. The high prevalence of antibiotic-resistant S. aureus strains necessitates a better understanding of the factors that govern host–pathogen interaction and cause bacterial resistance. Emerging evidence indicates the implication of microRNAs in antibiotic resistance, in the interaction between the pathogen and the host or as a mechanism of immune evasion. With this in mind, scientists of the EU-funded miRs4Staph project will characterise host microRNAs implicated in the interaction of S. aureus with the host. Through various interdisciplinary and innovative strategies, the project will identify and validate microRNAs involved in S. aureus infection that could serve as targets for the design of future therapeutic interventions.
Fields of science
Programme(s)
Funding Scheme
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
Coordinator
3004 517 Coimbra
Portugal
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