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Canonical and non-canonical secretory mechanisms of cytokines in bat and human cell cultures in response to coronavirus infection: a comparative study

Project description

Fighting coronavirus infections: lessons from bats

Now more than ever, it is paramount to understand how our bodies respond to coronaviruses (CoV) and what we need to do to fight them. Given that the highly pathogenic SARS- and MERS-CoV have emerged from bats, the EU-funded BatSECoV project will investigate the mechanism by which bats have developed a tolerance against CoV infections. Through a combination of molecular biology, cell biology and virology techniques, researchers will compare cytokine and interferon secretion in human and bat cells and identify the molecular players in these pathways. The project's results will serve as the basis for the future development of antiviral strategies to fight emerging zoonotic viruses.

Call for proposal

H2020-MSCA-IF-2019
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Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Address
Chariteplatz 1
10117 Berlin
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 162 806,40