UNCOVERING PATHOGENIC MICROPEPTIDES FROM THE HUMAN GENOME

Project description

Human genome pathogenic micropeptides

Recent studies have discovered a striking number of regions of the genome that are capable of being transcribed and translated into short polypeptides. These micropeptides comprise less than 100 amino acids, and more than 160 000 different micropeptides have been cataloged within human tissues so far. The current hypothesis is that these genome products might participate in numerous physiological processes, yet the function of only a few micropeptides has been clarified. The EU-funded GENOMEPEP project aims to identify particular micropeptides participating in the pathogenesis of cardiovascular diseases by analysing the genetic variation within the micropeptidome-encoding genome in correlation to existing common cardiovascular phenotypes in the population.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins
• medical and health sciences › clinical medicine › cardiology › cardiovascular diseases
• medical and health sciences › health sciences › personalized medicine
• natural sciences › chemical sciences › organic chemistry › amines
• natural sciences › biological sciences › genetics › genomes
• medical and health sciences › basic medicine › pharmacology and pharmacy

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019

See other projects for this call

Funding Scheme

MSCA-IF-EF-CAR - CAR – Career Restart panel

Coordinator

TARTU ULIKOOL

Net EU contribution

€ 213 289,92

Address

Ulikooli 18
51005 Tartu
Estonia

Region

Eesti › Eesti › Lõuna-Eesti

Activity type

Higher or Secondary Education Establishments

Links

Non-EU contribution

€ 0,00