Project description
Human genome pathogenic micropeptides
Recent studies have discovered a striking number of regions of the genome that are capable of being transcribed and translated into short polypeptides. These micropeptides comprise less than 100 amino acids, and more than 160 000 different micropeptides have been cataloged within human tissues so far. The current hypothesis is that these genome products might participate in numerous physiological processes, yet the function of only a few micropeptides has been clarified. The EU-funded GENOMEPEP project aims to identify particular micropeptides participating in the pathogenesis of cardiovascular diseases by analysing the genetic variation within the micropeptidome-encoding genome in correlation to existing common cardiovascular phenotypes in the population.
Fields of science
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- medical and health scienceshealth sciencespersonalized medicine
- natural scienceschemical sciencesorganic chemistryamines
- natural sciencesbiological sciencesgeneticsgenomes
- medical and health sciencesbasic medicinepharmacology and pharmacy
Programme(s)
Funding Scheme
MSCA-IF-EF-CAR - CAR – Career Restart panelCoordinator
51005 Tartu
Estonia
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