Molecules Inhibiting Translation in Cancer cells

Project Information

MITiC

Grant agreement ID: 895024

DOI

10.3030/895024

Project terminated on 30 September 2022

EC signature date 6 April 2020

Start date 1 November 2020

End date 31 October 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 184 707,84

EU contribution

€ 184 707,84

Coordinated by

UNIVERSITE D'EVRY-VAL D'ESSONE
France

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Conference proceedings (4)

Inhibiting RNA:Protein Interactions using an Integrative Computational and Experimental Approach: Application to Y Box Binding Protein 1

Author(s): El Hage, Krystel; Pastre, David
Published in: EMBO Workshop: Advances and Challenges in Biomolecular Simulations, 2021
Publisher: EMBO

Targeting RNA:Protein Interactions using an Integrative Approach: Identification of Potent YB-1 Inhibitors

Author(s): Krystel El Hage, David Pastre
Published in: ISQBP President’s meeting 2022, 2022, Page(s) 10
Publisher: ISQBP

Inhibiting RNA:Protein Interactions using an integrative computational and experimental approach: Application to Y-Box binding protein 1

Author(s): El Hage, Krystel; Pastre, David
Published in: ISQBP's President's meeting 2021, 2021, Page(s) 81
Publisher: ISQBP 2021

Inhibiting RNA : Protein Interactions using an Integrative Computational and Experimental Approach: Application to YB1

Author(s): El Hage, Krystel
Published in: 2020 Workshop on Free Energy Methods in Drug Design, 2021
Publisher: Alchemistry.org

Peer reviewed articles (3)

Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

Author(s): Anastasiia Samsonova, Krystel El Hage, Bénédicte Desforges, Vandana Joshi, Marie-Jeanne Clément, Guillaume Lambert, Hélène Henrie, Nicolas Babault, Pierrick Craveur, Rachid C. Maroun, Emilie Steiner, Ahmed Bouhss, Alexandre Maucuer, Dmitry N. Lyabin, Lev P. Ovchinnikov, Loic Hamon, David Pastré
Published in: Communications Biology, Issue 4/1, 2021, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-021-01862-3

YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

Author(s): Karina Budkina, Krystel El Hage, Marie-Jeanne Clément, Bénédicte Desforges, Ahmed Bouhss, Vandana Joshi, Alexandre Maucuer, Loic Hamon, Lev P Ovchinnikov, Dmitry N Lyabin, David Pastré
Published in: Nucleic Acid Research, Issue Volume 49, Issue 17, 2021, Page(s) Pages 10061–10081, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab748

Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors

Author(s): Krystel El Hage (Is a corresponding author), Nicolas Babault, Olek Maciejak, Bénédicte Desforges, Pierrick Craveur, Emilie Steiner, Juan Carlos Rengifo-Gonzalez, Hélène Henrie, Marie-Jeanne Clement, Vandana Joshi, Ahmed Bouhss, Liya Wang, Cyril Bauvais, David Pastré.
Published in: elife, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.80387

Non-peer reviewed articles (1)

Targeting RNA:Protein Interactions with an Integrative Approach Leads to the Identification of Potent YB-1 Inhibitors

Author(s): Krystel El Hage, Nicolas Babault, Olek Maciejak, Bénédicte Desforges, Pierrick Craveur, Emilie Steiner, Juan Carlos Rengifo-Gonzalez, Hélène Henrie, Marie-Jeanne Clément, Vandana Joshi, Ahmed Bouhss, Liya Wang, Cyril Bauvais, David Pastré
Published in: BioRxiv, 2022, ISSN 2692-8205
Publisher: BioRxiv
DOI: 10.1101/2022.04.08.487452