Insight into cilia assembly and function
Cilia are conserved cell surface organelles composed of microtubules. They have diverse motility and sensory functions, and defects in their assembly lead to conditions known as ciliopathies. The EU-funded ResolvCiliaTip project will focus on the CCDC66 protein, a recently identified ciliary tip component implicated in progressive retinal degeneration, to provide insight into ciliary microtubule dynamics. Scientists aim to unveil the localisation and function of CCDC66, contributing to the improved characterisation of the causative genes of ciliopathies. Apart from providing fundamental knowledge, the project's results will lay the foundation for enhanced diagnostic approaches in future.
Field of science
- /natural sciences/biological sciences/biochemistry/biomolecules/proteins
- /natural sciences/mathematics/pure mathematics/geometry
Call for proposal
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