Project description DEENESFRITPL New models will help nanotechnology deliver benefits without hidden costs Nanotechnology is based on harnessing the amazing and unique properties some materials can exhibit when they are present as incredibly small constituents, properties that are not seen when these materials are in bulk form. However, the very small dimensions of nanomaterials enable them to cross important barriers in living organisms, raising issues about where they go, how long they stay there, what happens to them over time and what effects they might have. The EU-funded NanoQSAR project is filling an important gap in the effective risk assessment of nanomaterials. The development of advanced quantitative structure–activity relationship models will facilitate the prediction of the physicochemical, biological and environmental fate properties of engineered nanomaterials, significantly enhancing the field of nanotoxicology and human and environmental safety. Show the project objective Hide the project objective Objective Nanotechnology is one of the fastest growing and most promising technologies in our society (Forster et al. 2011), promoting the development a new generation of smart and innovative products and processes that have created tremendous growth potential for a large number of industry sectors such as composites, colouring, ceramics, electronics, nutrition, cosmetics, energy, optics, automotive, as well as numerous other industrial sectors.Currently, there is a need of ensuring a safe and sustainable development of the nanotechnology, which implies a better understanding of the potential harmful effects that ENMs may have on human´s health or the environment. New paradigms are necessary to identify high concern ENMs and predict relevant endpoints for risk assessment, reducing the cost andtimescale derived from the use of in vivo or in vitro assays.QSAR approaches have only recently been used to predict biological effects of ENMs, with only few Quantitative Nano- Structure Activity Relationships models described in the literature. The lack of available data explains why there is almost no literature reporting the use of computational modelling techniques applied to ENMs, especially in the area of nanotoxicology. On the other hand, current toxicological regulation, such as the Registration, Evaluation, Authorisation and Restriction ofChemicals (REACH), strongly promotes the use of these predictive modelling.On the basis of the concept of the project, the main objective of the Nano-QSAR project is to develop new scientifically validated QSARs models to predict REACH relevant toxicological, ecotoxicological and environmental endpoints of a priority list of ENMs such as Metal Oxide Nanoparticles (MOx) and Quantum Dots (QD) on the basis of available literature and own experimental data. Fields of science engineering and technologymaterials engineeringcompositesnatural scienceschemical sciencesinorganic chemistryinorganic compoundsmedical and health scienceshealth sciencesnutritionengineering and technologynanotechnologynano-materialsengineering and technologymaterials engineeringceramics Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2019 - Individual Fellowships Call for proposal H2020-MSCA-IF-2019 See other projects for this call Funding Scheme MSCA-IF-EF-SE - Society and Enterprise panel Coordinator PROTOQSAR 2000 SL Net EU contribution € 172 932,48 Address C salvador ferrandis luna 45 pta 23 46018 Valencia Spain See on map Region Este Comunitat Valenciana Valencia/València Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
