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AN INTERDISCIPLINARY APPROACH FOR THE MANAGEMENT OF THE ELDERLY MULTIMORBID PATIENT WITH BREAST CANCER THERAPY INDUCED CARDIAC TOXICITY

Project description

An innovative solution for treating elderly breast cancer patients at risk for cardiotoxicity

Age-related factors and co-morbidities increase elderly breast cancer patients' vulnerability to cardiotoxicity during cancer treatment. Lack of best practices and frailty bias in these patients, underrepresented in trials, may lead to inappropriate interventions and undertreatment, resulting in poorer outcomes, deterioration of quality of life and increased healthcare costs. The EU-funded CARDIOCARE project will focus on the elderly breast cancer population. Through a holistic approach including eHealth applications, wearable sensors and biomarkers it will enable patients to take part in their care process and enhance their physical and mental health, contributing to an individualised care plan and a psychological adaptation to their disease. CARDIOCARE will enable effective risk stratification, mitigating cardiotoxicity and adverse events, minimising hospitalisation and enhancing quality of life.

Objective

More than 50% of the newly diagnosed breast cancer patients are elderly and particularly susceptible to cardiotoxicity of cancer treatment due to age-related factors and prevalence of multiple co-morbidities. The cumulative effect of risk factors in the elderly patient resembles a “snowball effect”, where baseline age and cancer-related changes are exacerbated by direct therapy-induced cardiotoxicity, resulting to a multi-morbid state and mortality. Frailty and high risk of cardiotoxicity in this group may lead to inappropriate interventions and undertreatment, resulting in poorer outcomes, deterioration of QoL and increased healthcare costs. Considering, that older cancer patients are underrepresented in trials, new interdisciplinary and patient-oriented studies able to provide clinical guidelines and best practices for delivering quality care are needed.
CARDIOCARE will contribute to scale up a better management for the multimorbid elderly breast cancer patients. Innovative eHealth applications, coupled with sensors and wearables, will permit a consistent evaluation of the intrinsic capacity and by combining clinical and biological features, will provide a holistic approach to the management of cancer and his co-morbidities in the elderly population. This will allow the development of quality indicators for effective care pathways and allow a more informed approach to breast cancer patients with multimorbidity, training and education of caregivers and stakeholders to boost effectively elderly breast cancer patients along disease trajectory and cardiotoxicity. eHealth applications will increase the involvement and participation of the patients in their care process and self-management improving adherence to their individualized care plan, and a better psychological adaptation to their disease. Overall, the implementation of a comprehensive model for effective risk stratification will positively impact on QoL, adverse events, hospitalizations, and healthcare.

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Topic(s)

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RIA - Research and Innovation action

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Call for proposal

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(opens in new window) H2020-SC1-BHC-2018-2020

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Coordinator

PANEPISTIMIO IOANNINON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 290 000,00
Address
PANEPISTEMIOYPOLE PANEPISTEMIO IOANNINON
45 110 IOANNINA
Greece

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 290 000,00

Participants (11)

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