The Fluctuating Enzyme: From Catalysis to Vibrational Dynamics

Project Information

FLUCTENZ

Grant agreement ID: 947731

DOI

10.3030/947731

EC signature date 20 August 2020

Start date 1 August 2021

End date 31 July 2027

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 496 875,00

EU contribution

€ 1 496 875,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (26)

Inference of non-exponential kinetics through stochastic resetting

Author(s): Ofir Blumer, Shlomi Reuveni, Barak Hirshberg
Published in: The Journal of Chemical Physics, Issue 161, 2025, ISSN 0021-9606
Publisher: American Institute of Physics
DOI: 10.1063/5.0243783

Sokoban percolation on the Bethe lattice

Author(s): Ofek Lauber Bonomo, Itamar Shitrit, Shlomi Reuveni
Published in: Journal of Physics A: Mathematical and Theoretical, Issue 57, 2024, Page(s) 33LT01, ISSN 1751-8113
Publisher: Institute of Physics Publishing
DOI: 10.1088/1751-8121/ad6380

Adaptive Resetting for Informed Search Strategies and the Design of Non-equilibrium Steady-States

Author(s): Shlomi Reuveni, Tommer Keidar, Ofir Blumer, Barak Hirshberg
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.21203/rs.3.rs-5173132/v1

The inspection paradox in stochastic resetting

Author(s): Arnab Pal; Sarah Kostinski; Shlomi Reuveni
Published in: Journal of Physics A: Mathematical and Theoretical, 2022, ISSN 1751-8121
Publisher: Institute of Physics
DOI: 10.1088/1751-8121/ac3cdf

Diffusion with partial resetting

Author(s): Ofir Tal-Friedman, Yael Roichman, and Shlomi Reuveni
Published in: Physical Review E, 2022, ISSN 2470-0053
Publisher: American Physical Society
DOI: 10.1103/physreve.106.054116

First-passage approach to optimizing perturbations for improved training of machine learning models

Author(s): Sagi Meir, Tommer D Keidar, Shlomi Reuveni, Barak Hirshberg
Published in: Machine Learning: Science and Technology, Issue 6, 2025, Page(s) 025053, ISSN 2632-2153
Publisher: IOP Publishing
DOI: 10.1088/2632-2153/add8df

Continuous gated first-passage processes

Author(s): Yuval Scher, Aanjaneya Kumar, M S Santhanam, Shlomi Reuveni
Published in: Reports on Progress in Physics, Issue 87, 2024, Page(s) 108101, ISSN 0034-4885
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6633/ad7530

Enzymatic Activity Profiling Using an Ultrasensitive Array of Chemiluminescent Probes for Bacterial Classification and Characterization

Author(s): Omri Shelef, Tal Kopp, Rozan Tannous, Maxence Arutkin, Moriah Jospe-Kaufman, Shlomi Reuveni, Doron Shabat, and Micha Fridman
Published in: Journal of the American Chemical Society, Issue 146, 2024, ISSN 1520-5126
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c11790

Combining stochastic resetting with Metadynamics to speed-up molecular dynamics simulations

Author(s): Ofir Blumer, Shlomi Reuveni, Barak Hirshberg
Published in: Nature communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44528-w

Microscopic theory of adsorption kinetics

Author(s): Yuval Scher, Ofek Lauber Bonomo, Arnab Pal, Shlomi Reuveni
Published in: The Journal of Chemical Physics, 2023, ISSN 1089-7690
Publisher: American Institute of Physics
DOI: 10.1063/5.0121359

Doubly stochastic continuous time random walk

Author(s): Arutkin, Maxence; Reuveni, Shlomi
Published in: Phys. Rev. Research, Issue 2, 2023, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.6.l012033

Short-Time Infrequent Metadynamics for Improved Kinetics Inference

Author(s): Ofir Blumer; Shlomi Reuveni; Barak Hirshberg
Published in: J. Chem. Theory Comput., Issue 20, 9, 2024, Page(s) 3484, ISSN 1549-9626
Publisher: American Chemical Society
DOI: 10.1021/acs.jctc.4c00170

Loss of percolation transition in the presence of simple tracer-media interactions

Author(s): Ofek Lauber Bonomo; Shlomi Reuveni
Published in: Phys. Rev. Research, Issue 2, 2023, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.5.l042015

Inference from gated first-passage times

Author(s): Aanjaneya Kumar; Yuval Scher; Shlomi Reuveni; M. S. Santhanam
Published in: Phys. Rev. Research, Issue 2, 2023, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.5.l032043

Stochastic Resetting for Enhanced Sampling

Author(s): Ofir Blumer; Shlomi Reuveni; Barak Hirshberg
Published in: The Journal of Physical Chemistry Letters, Issue 2, 2022, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.2c03055

Queues with service resetting

Author(s): Ofek Lauber Bonomo, Uri Yechiali, Shlomi Reuveni
Published in: European Journal of Operational Research, Issue 322, 2025, Page(s) 908-919, ISSN 0377-2217
Publisher: Elsevier BV
DOI: 10.1016/j.ejor.2024.12.044

Smart resetting: An energy-efficient strategy for stochastic search processes

Author(s): Ofir Tal-Friedman, Tommer D. Keidar, Shlomi Reuveni, Yael Roichman
Published in: Physical Review Research, Issue 7, 2025, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/physrevresearch.7.013033

Accelerating Molecular Dynamics through Informed Resetting

Author(s): Jonathan R. Church, Ofir Blumer, Tommer D. Keidar, Leo Ploutno, Shlomi Reuveni, Barak Hirshberg
Published in: Journal of Chemical Theory and Computation, Issue 21, 2025, Page(s) 605-613, ISSN 1549-9618
Publisher: American Chemical Society
DOI: 10.1021/acs.jctc.4c01238

Escape from textured adsorbing surfaces

Author(s): Scher, Yuval; Reuveni, Shlomi; Grebenkov, Denis S.
Published in: J. Chem. Phys., Issue 160, 2024, Page(s) 184105, ISSN 0021-9606
Publisher: American Institute of Physics
DOI: 10.1063/5.0196981

High-order Michaelis-Menten equations allow inference of hidden kinetic parameters in enzyme catalysis

Author(s): Divya Singh, Tal Robin, Michael Urbakh, Shlomi Reuveni
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-57327-2

Escape of a sticky particle

Author(s): Yuval Scher; Shlomi Reuveni; Denis S. Grebenkov
Published in: Phys. Rev. Research, Issue 5, 2023, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.5.043196

Diversity of sharp restart

Author(s): Iddo Eliazar, Shlomi Reuveni
Published in: Journal of Physics A: Mathematical and Theoretical, 2023, ISSN 1751-8121
Publisher: Institute of Physics
DOI: 10.1088/1751-8121/acb184

Mitigating long queues and waiting times with service resetting

Author(s): Shlomi Reuveni; Ofek Lauber; Arnab Pal
Published in: PNAS NEXUS, Issue 5, 2022, ISSN 2752-6542
Publisher: Oxford Academic
DOI: 10.1093/pnasnexus/pgac070

Entropy of sharp restart

Author(s): Iddo Eliazar, Shlomi Reuveni
Published in: Journal of Physics A: Mathematical and Theoretical, 2023, ISSN 1751-8121
Publisher: Institute of Physics
DOI: 10.1088/1751-8121/acb183

Environmental memory facilitates search with home returns

Author(s): Altshuler, Amy; Bonomo, Ofek Lauber; Gorohovsky, Nicole; Marchini, Shany; Rosen, Eran; Tal-Friedman, Ofir; Reuveni, Shlomi; Roichman, Yael
Published in: Phys. Rev. Research, Issue 6, 2024, Page(s) 023255, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.6.023255

Quantifying transmembrane water exchange by diffusion NMR methods: From yeast cells to optic nerve ex vivo

Author(s): Yuval Scher, Shlomi Reuveni, Yoram Cohen
Published in: Nmr in Biomedicine, 2026, ISSN 1099-1492
Publisher: Wiley
DOI: 10.1101/2025.06.01.657299

Non-peer reviewed articles (1)

Preface: stochastic resetting—theory and applications

Author(s): Anupam Kundu; Shlomi Reuveni
Published in: Journal of Physics A: Mathematical and Theoretical, Issue 2, 2024, ISSN 1751-8121
Publisher: IOP Publishing
DOI: 10.1088/1751-8121/ad1e1b