Multifunctional Personalized Self-Assembled Biomaterials for Bone Regeneration

Project Information

PersonalBone

Grant agreement ID: 948102

DOI

10.3030/948102

EC signature date 18 November 2020

Start date 1 January 2021

End date 31 December 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 375,00

EU contribution

€ 1 499 375,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (20)

Molecular engineering of rigid hydrogels co-assembled from collagenous helical peptides based on a single triplet motif

Author(s): Santu Bera; Pierre-Andre Cazade; Shayon Bhattacharya; Sarah Guerin; Moumita Ghosh; Francesca Netti; Damien Thompson; Lihi Adler-Abramovich
Published in: ACS Applied Material Interfaces, Issue 14, 2022, Page(s) 46827–46840, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.34961/researchrepository-ul.22232041

Effect of solvent-induced packing transitions on N-capped diphenylalanine peptide crystal growth

Author(s): Yoav Dan, Zohar A. Arnon, Yiming Tang, Mathar Kravikass, Yun Zhou, Rajkumar Misra, Om Shanker Tiwari, Linda J. W. Shimon, Roy Beck, Ehud Gazit, Guanghong Wei, Lihi Adler-Abramovich
Published in: Nature Communications, Issue 16, 2025, Page(s) 6106, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-61331-x

Conductive Peptide‐Based MXene Hydrogel as a Piezoresistive Sensor

Author(s): Dana Cohen‐Gerassi, Or Messer, Gal Finkelstein‐Zuta, Moran Aviv, Bar Favelukis, Yosi Shacham‐Diamand, Maxim Sokol, Lihi Adler‐Abramovich
Published in: Advanced Healthcare Materials, Issue 13, 2024, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202303632

Molecular Co‐Assembly of Two Building Blocks Harnesses Both their Attributes into a Functional Supramolecular Hydrogel

Author(s): Priyadarshi Chakraborty; Moran Aviv; Francesca Netti; Dana Cohen‐Gerassi; Lihi Adler‐Abramovich
Published in: Macromolecular Bioscience, Issue 1, 2022, Page(s) 2100439, ISSN 1616-5195
Publisher: Wiley-VCH
DOI: 10.1002/mabi.202100439

Mechanical Enhancement and Kinetics Regulation of Fmoc-Diphenylalanine Hydrogels by Thioflavin T.

Author(s): Tatiana N. Tikhonova; Nataliya N. Rovnyagina; Zohar A. Arnon; Boris P. Yakimov; Boris P. Yakimov; Yuri M. Efremov; Dana Cohen-Gerassi; Michal Halperin-Sternfeld; Nastasia V. Kosheleva; Vladimir P. Drachev; Andrey A. Svistunov; Peter S. Timashev; Lihi Adler-Abramovich; Evgeny A. Shirshin; Evgeny A. Shirshin
Published in: Angewandte Chemie International Edition, Issue 60, 2021, Page(s) 25339-25345, ISSN 1521-3773
Publisher: German Chemical Society
DOI: 10.1002/anie.202107063

Immunomodulatory fibrous hyaluronic acid‐ <scp>Fmoc</scp> ‐diphenylalanine‐based hydrogel induces bone regeneration

Author(s): Michal Halperin‐Sternfeld; Ariel Pokhojaev; Moumita Ghosh; Dana Rachmiel; Raha Kannan; Itzhak Grinberg; Moshe Asher; Moran Aviv; Peter X. Ma; Itzhak Binderman; Rachel Sarig; Lihi Adler‐Abramovich
Published in: Journal of Clinical Periodontology, Issue 50, 2023, Page(s) 200-219, ISSN 1600-051X
Publisher: John Wiley & Sons.
DOI: 10.1111/jcpe.13725

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Author(s): Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich
Published in: Advanced Functional Materials, 2025, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202501745

Modification of a Single Atom Affects the Physical Properties of Double Fluorinated Fmoc-Phe Derivatives

Author(s): Moran Aviv; Dana Cohen-Gerassi; Asuka A. Orr; Rajkumar Misra; Zohar A. Arnon; Linda J. W. Shimon; Yosi Shacham-Diamand; Phanourios Tamamis; Lihi Adler-Abramovich
Published in: International Journal of Molecular Sciences, Issue 22, 2021, Page(s) 9634, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179634

Stabilizing Gelatin-Based Bioinks under Physiological Conditions by Incorporation of Ethylene-Glycol-Conjugated Fmoc-FF Peptides

Author(s): Francesca Netti; Moran Aviv; Yoav Dan; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich
Published in: Nanoscale, Issue 14, 2022, Page(s) 8525, ISSN 2040-3372
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1nr08206j

Positional Fluorination of Fmoc-Phenylalanine Modulates Hydrogel Structure and Antibacterial Activity

Author(s): Ofir Doitch, Noam Rattner, Dana Cohen-Gerassi, Yoav Dan, Sigal Rencus-Lazar, Moran Aviv, Lihi Adler-Abramovich
Published in: Biomacromolecules, 2025, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.5c00481

Disordered Protein Stabilization by Co-Assembly of Short Peptides Enables Formation of Robust Membranes

Author(s): Moumita Ghosh; Anna Majkowska; Rajkumar Mirsa; Santu Bera; José Carlos Rodríguez-Cabello; Alvaro Mata; Lihi Adler-Abramovich
Published in: ACS Applied Materials Interfaces, Issue 14, 2022, Page(s) 464–473, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.1c22136

Modulating hierarchical self-assembly in thermoresponsive intrinsically disordered proteins through high-temperature incubation time

Author(s): Vaishali Sethi, Dana Cohen-Gerassi, Sagi Meir, Max Ney, Yulia Shmidov, Gil Koren, Lihi Adler-Abramovich, Ashutosh Chilkoti & Roy Beck
Published in: Scientific Reports, Issue 13, 2023, Page(s) 21688, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-48483-w

Exploiting Minimalistic Backbone Engineered ?-Phenylalanine for the Formation of Supramolecular Co-Polymer

Author(s): Rajkumar Misra; Yiming Tang; Yujie Chen; Priyadarshi Chakraborty; Francesca Netti; Thangavel Vijayakanth; Linda J. W. Shimon; Guanghong Wei; Lihi Adler-Abramovich
Published in: Macromolecular Rapid Communications, Issue 1, 2022, Page(s) 2200223, ISSN 1521-3927
Publisher: Wiley-VCH GmbH
DOI: 10.1002/marc.202200223

An atomistic view of rigid crystalline supramolecular polymers derived from short amphiphilic, α,β hybrid peptide

Author(s): Rajkumar Misra; Francesca Netti; Gil Koren; Yoav Dan; Priyadarshi Chakraborty; Sidney R. Cohen; Linda J. W. Shimon; Roy Beck; Lihi Adler-Abramovich
Published in: Polymer Chemistry, Issue 13, 2022, Page(s) 6223-6228, ISSN 1759-9962
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2py01072k

Atomic Insight into Short Helical Peptide Comprised of Consecutive Multiple Aromatic Residues

Author(s): Rajkumar Misra; Thangavel Vijayakanth; Linda J W Shimon; Lihi Adler-Abramovich
Published in: Chemical Communications, Issue 58, 2022, Page(s) 6445-6448, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc01038k

Hyaluronic Acid and a Short Peptide Improve the Performance of a PCL Electrospun Fibrous Scaffold Designed for Bone Tissue Engineering Applications

Author(s): Dana Rachmiel; Inbar Anconina; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich; Amit Sitt
Published in: International Journal of Molecular Sciences, Issue 22, 2021, Page(s) 242, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22052425

The Effects of a Short Self-Assembling Peptide on the Physical and Biological Properties of Biopolymer Hydrogels

Author(s): Chowdhuri, S., Ghosh, M., Adler-Abramovich, L.*, Das, D
Published in: Pharmaceutics, Issue 13, 2021, Page(s) 1602, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101602

In Vitro Evaluation of a Semi‐Autologous Fibrin Sealant for Surgical Applications

Author(s): Uri Elbaz, Ori Berliner, Shavit Tabo, Shani Yeshayahu, Reut Kesner, Dana Cohen‐Gerassi, Lihi Adler‐Abramovich, Michal Halperin‐Sternfeld, Moran Aviv
Published in: Macromolecular Bioscience, Issue 25, 2025, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202400165

Red Microalgae Sulfated Polysaccharide-Peptide Composite Hydrogels as Scaffolds for Tissue Engineering

Author(s): Michal Halperin-Sternfeld; Gal Netanel Liberman; Raha Kannan; Francesca Netti; Peter X Ma; Shoshana Malis Arad; Lihi Adler-Abramovich
Published in: Biomedicines, Issue 10, 2022, Page(s) 1388, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines10061388

Unveiling the Assembly Transition of Diphenylalanine and Its Analogs: from Oligomer Equilibrium to Nanocluster Formation

Author(s): Chang Liu, Yoav Dan, Ji Yun, Lihi Adler-Abramovich, Jinghui Luo
Published in: ACS Nano, Issue 19, 2025, Page(s) 13250-13263, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.5c00433