Multifunctional Personalized Self-Assembled Biomaterials for Bone Regeneration

Informazioni relative al progetto

PersonalBone

ID dell’accordo di sovvenzione: 948102

DOI

10.3030/948102

Data della firma CE 18 Novembre 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Dicembre 2026

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 499 375,00

Contributo UE

€ 1 499 375,00

Coordinato da

TEL AVIV UNIVERSITY
Israel

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (20)

Molecular engineering of rigid hydrogels co-assembled from collagenous helical peptides based on a single triplet motif

Autori: Santu Bera; Pierre-Andre Cazade; Shayon Bhattacharya; Sarah Guerin; Moumita Ghosh; Francesca Netti; Damien Thompson; Lihi Adler-Abramovich
Pubblicato in: ACS Applied Material Interfaces, Numero 14, 2022, Pagina/e 46827–46840, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.34961/researchrepository-ul.22232041

Effect of solvent-induced packing transitions on N-capped diphenylalanine peptide crystal growth

Autori: Yoav Dan, Zohar A. Arnon, Yiming Tang, Mathar Kravikass, Yun Zhou, Rajkumar Misra, Om Shanker Tiwari, Linda J. W. Shimon, Roy Beck, Ehud Gazit, Guanghong Wei, Lihi Adler-Abramovich
Pubblicato in: Nature Communications, Numero 16, 2025, Pagina/e 6106, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-61331-x

Conductive Peptide‐Based MXene Hydrogel as a Piezoresistive Sensor

Autori: Dana Cohen‐Gerassi, Or Messer, Gal Finkelstein‐Zuta, Moran Aviv, Bar Favelukis, Yosi Shacham‐Diamand, Maxim Sokol, Lihi Adler‐Abramovich
Pubblicato in: Advanced Healthcare Materials, Numero 13, 2024, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202303632

Molecular Co‐Assembly of Two Building Blocks Harnesses Both their Attributes into a Functional Supramolecular Hydrogel

Autori: Priyadarshi Chakraborty; Moran Aviv; Francesca Netti; Dana Cohen‐Gerassi; Lihi Adler‐Abramovich
Pubblicato in: Macromolecular Bioscience, Numero 1, 2022, Pagina/e 2100439, ISSN 1616-5195
Editore: Wiley-VCH
DOI: 10.1002/mabi.202100439

Mechanical Enhancement and Kinetics Regulation of Fmoc-Diphenylalanine Hydrogels by Thioflavin T.

Autori: Tatiana N. Tikhonova; Nataliya N. Rovnyagina; Zohar A. Arnon; Boris P. Yakimov; Boris P. Yakimov; Yuri M. Efremov; Dana Cohen-Gerassi; Michal Halperin-Sternfeld; Nastasia V. Kosheleva; Vladimir P. Drachev; Andrey A. Svistunov; Peter S. Timashev; Lihi Adler-Abramovich; Evgeny A. Shirshin; Evgeny A. Shirshin
Pubblicato in: Angewandte Chemie International Edition, Numero 60, 2021, Pagina/e 25339-25345, ISSN 1521-3773
Editore: German Chemical Society
DOI: 10.1002/anie.202107063

Immunomodulatory fibrous hyaluronic acid‐ <scp>Fmoc</scp> ‐diphenylalanine‐based hydrogel induces bone regeneration

Autori: Michal Halperin‐Sternfeld; Ariel Pokhojaev; Moumita Ghosh; Dana Rachmiel; Raha Kannan; Itzhak Grinberg; Moshe Asher; Moran Aviv; Peter X. Ma; Itzhak Binderman; Rachel Sarig; Lihi Adler‐Abramovich
Pubblicato in: Journal of Clinical Periodontology, Numero 50, 2023, Pagina/e 200-219, ISSN 1600-051X
Editore: John Wiley & Sons.
DOI: 10.1111/jcpe.13725

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Autori: Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich
Pubblicato in: Advanced Functional Materials, 2025, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202501745

Modification of a Single Atom Affects the Physical Properties of Double Fluorinated Fmoc-Phe Derivatives

Autori: Moran Aviv; Dana Cohen-Gerassi; Asuka A. Orr; Rajkumar Misra; Zohar A. Arnon; Linda J. W. Shimon; Yosi Shacham-Diamand; Phanourios Tamamis; Lihi Adler-Abramovich
Pubblicato in: International Journal of Molecular Sciences, Numero 22, 2021, Pagina/e 9634, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179634

Stabilizing Gelatin-Based Bioinks under Physiological Conditions by Incorporation of Ethylene-Glycol-Conjugated Fmoc-FF Peptides

Autori: Francesca Netti; Moran Aviv; Yoav Dan; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich
Pubblicato in: Nanoscale, Numero 14, 2022, Pagina/e 8525, ISSN 2040-3372
Editore: Royal Society of Chemistry
DOI: 10.1039/d1nr08206j

Positional Fluorination of Fmoc-Phenylalanine Modulates Hydrogel Structure and Antibacterial Activity

Autori: Ofir Doitch, Noam Rattner, Dana Cohen-Gerassi, Yoav Dan, Sigal Rencus-Lazar, Moran Aviv, Lihi Adler-Abramovich
Pubblicato in: Biomacromolecules, 2025, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.5c00481

Disordered Protein Stabilization by Co-Assembly of Short Peptides Enables Formation of Robust Membranes

Autori: Moumita Ghosh; Anna Majkowska; Rajkumar Mirsa; Santu Bera; José Carlos Rodríguez-Cabello; Alvaro Mata; Lihi Adler-Abramovich
Pubblicato in: ACS Applied Materials Interfaces, Numero 14, 2022, Pagina/e 464–473, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.1c22136

Modulating hierarchical self-assembly in thermoresponsive intrinsically disordered proteins through high-temperature incubation time

Autori: Vaishali Sethi, Dana Cohen-Gerassi, Sagi Meir, Max Ney, Yulia Shmidov, Gil Koren, Lihi Adler-Abramovich, Ashutosh Chilkoti & Roy Beck
Pubblicato in: Scientific Reports, Numero 13, 2023, Pagina/e 21688, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-48483-w

Exploiting Minimalistic Backbone Engineered ?-Phenylalanine for the Formation of Supramolecular Co-Polymer

Autori: Rajkumar Misra; Yiming Tang; Yujie Chen; Priyadarshi Chakraborty; Francesca Netti; Thangavel Vijayakanth; Linda J. W. Shimon; Guanghong Wei; Lihi Adler-Abramovich
Pubblicato in: Macromolecular Rapid Communications, Numero 1, 2022, Pagina/e 2200223, ISSN 1521-3927
Editore: Wiley-VCH GmbH
DOI: 10.1002/marc.202200223

An atomistic view of rigid crystalline supramolecular polymers derived from short amphiphilic, α,β hybrid peptide

Autori: Rajkumar Misra; Francesca Netti; Gil Koren; Yoav Dan; Priyadarshi Chakraborty; Sidney R. Cohen; Linda J. W. Shimon; Roy Beck; Lihi Adler-Abramovich
Pubblicato in: Polymer Chemistry, Numero 13, 2022, Pagina/e 6223-6228, ISSN 1759-9962
Editore: Royal Society of Chemistry
DOI: 10.1039/d2py01072k

Atomic Insight into Short Helical Peptide Comprised of Consecutive Multiple Aromatic Residues

Autori: Rajkumar Misra; Thangavel Vijayakanth; Linda J W Shimon; Lihi Adler-Abramovich
Pubblicato in: Chemical Communications, Numero 58, 2022, Pagina/e 6445-6448, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cc01038k

Hyaluronic Acid and a Short Peptide Improve the Performance of a PCL Electrospun Fibrous Scaffold Designed for Bone Tissue Engineering Applications

Autori: Dana Rachmiel; Inbar Anconina; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich; Amit Sitt
Pubblicato in: International Journal of Molecular Sciences, Numero 22, 2021, Pagina/e 242, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22052425

The Effects of a Short Self-Assembling Peptide on the Physical and Biological Properties of Biopolymer Hydrogels

Autori: Chowdhuri, S., Ghosh, M., Adler-Abramovich, L.*, Das, D
Pubblicato in: Pharmaceutics, Numero 13, 2021, Pagina/e 1602, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101602

In Vitro Evaluation of a Semi‐Autologous Fibrin Sealant for Surgical Applications

Autori: Uri Elbaz, Ori Berliner, Shavit Tabo, Shani Yeshayahu, Reut Kesner, Dana Cohen‐Gerassi, Lihi Adler‐Abramovich, Michal Halperin‐Sternfeld, Moran Aviv
Pubblicato in: Macromolecular Bioscience, Numero 25, 2025, ISSN 1616-5187
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202400165

Red Microalgae Sulfated Polysaccharide-Peptide Composite Hydrogels as Scaffolds for Tissue Engineering

Autori: Michal Halperin-Sternfeld; Gal Netanel Liberman; Raha Kannan; Francesca Netti; Peter X Ma; Shoshana Malis Arad; Lihi Adler-Abramovich
Pubblicato in: Biomedicines, Numero 10, 2022, Pagina/e 1388, ISSN 2227-9059
Editore: MDPI
DOI: 10.3390/biomedicines10061388

Unveiling the Assembly Transition of Diphenylalanine and Its Analogs: from Oligomer Equilibrium to Nanocluster Formation

Autori: Chang Liu, Yoav Dan, Ji Yun, Lihi Adler-Abramovich, Jinghui Luo
Pubblicato in: ACS Nano, Numero 19, 2025, Pagina/e 13250-13263, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.5c00433