Multifunctional Personalized Self-Assembled Biomaterials for Bone Regeneration

Información del proyecto

PersonalBone

Identificador del acuerdo de subvención: 948102

DOI

10.3030/948102

Fecha de la firma de la CE 18 Noviembre 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 31 Diciembre 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 499 375,00

Aportación de la UE

€ 1 499 375,00

Coordinado por

TEL AVIV UNIVERSITY
Israel

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (20)

Molecular engineering of rigid hydrogels co-assembled from collagenous helical peptides based on a single triplet motif

Autores: Santu Bera; Pierre-Andre Cazade; Shayon Bhattacharya; Sarah Guerin; Moumita Ghosh; Francesca Netti; Damien Thompson; Lihi Adler-Abramovich
Publicado en: ACS Applied Material Interfaces, Edición 14, 2022, Página(s) 46827–46840, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.34961/researchrepository-ul.22232041

Effect of solvent-induced packing transitions on N-capped diphenylalanine peptide crystal growth

Autores: Yoav Dan, Zohar A. Arnon, Yiming Tang, Mathar Kravikass, Yun Zhou, Rajkumar Misra, Om Shanker Tiwari, Linda J. W. Shimon, Roy Beck, Ehud Gazit, Guanghong Wei, Lihi Adler-Abramovich
Publicado en: Nature Communications, Edición 16, 2025, Página(s) 6106, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-61331-x

Conductive Peptide‐Based MXene Hydrogel as a Piezoresistive Sensor

Autores: Dana Cohen‐Gerassi, Or Messer, Gal Finkelstein‐Zuta, Moran Aviv, Bar Favelukis, Yosi Shacham‐Diamand, Maxim Sokol, Lihi Adler‐Abramovich
Publicado en: Advanced Healthcare Materials, Edición 13, 2024, ISSN 2192-2640
Editor: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202303632

Molecular Co‐Assembly of Two Building Blocks Harnesses Both their Attributes into a Functional Supramolecular Hydrogel

Autores: Priyadarshi Chakraborty; Moran Aviv; Francesca Netti; Dana Cohen‐Gerassi; Lihi Adler‐Abramovich
Publicado en: Macromolecular Bioscience, Edición 1, 2022, Página(s) 2100439, ISSN 1616-5195
Editor: Wiley-VCH
DOI: 10.1002/mabi.202100439

Mechanical Enhancement and Kinetics Regulation of Fmoc-Diphenylalanine Hydrogels by Thioflavin T.

Autores: Tatiana N. Tikhonova; Nataliya N. Rovnyagina; Zohar A. Arnon; Boris P. Yakimov; Boris P. Yakimov; Yuri M. Efremov; Dana Cohen-Gerassi; Michal Halperin-Sternfeld; Nastasia V. Kosheleva; Vladimir P. Drachev; Andrey A. Svistunov; Peter S. Timashev; Lihi Adler-Abramovich; Evgeny A. Shirshin; Evgeny A. Shirshin
Publicado en: Angewandte Chemie International Edition, Edición 60, 2021, Página(s) 25339-25345, ISSN 1521-3773
Editor: German Chemical Society
DOI: 10.1002/anie.202107063

Immunomodulatory fibrous hyaluronic acid‐ <scp>Fmoc</scp> ‐diphenylalanine‐based hydrogel induces bone regeneration

Autores: Michal Halperin‐Sternfeld; Ariel Pokhojaev; Moumita Ghosh; Dana Rachmiel; Raha Kannan; Itzhak Grinberg; Moshe Asher; Moran Aviv; Peter X. Ma; Itzhak Binderman; Rachel Sarig; Lihi Adler‐Abramovich
Publicado en: Journal of Clinical Periodontology, Edición 50, 2023, Página(s) 200-219, ISSN 1600-051X
Editor: John Wiley & Sons.
DOI: 10.1111/jcpe.13725

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Autores: Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich
Publicado en: Advanced Functional Materials, 2025, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202501745

Modification of a Single Atom Affects the Physical Properties of Double Fluorinated Fmoc-Phe Derivatives

Autores: Moran Aviv; Dana Cohen-Gerassi; Asuka A. Orr; Rajkumar Misra; Zohar A. Arnon; Linda J. W. Shimon; Yosi Shacham-Diamand; Phanourios Tamamis; Lihi Adler-Abramovich
Publicado en: International Journal of Molecular Sciences, Edición 22, 2021, Página(s) 9634, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179634

Stabilizing Gelatin-Based Bioinks under Physiological Conditions by Incorporation of Ethylene-Glycol-Conjugated Fmoc-FF Peptides

Autores: Francesca Netti; Moran Aviv; Yoav Dan; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich
Publicado en: Nanoscale, Edición 14, 2022, Página(s) 8525, ISSN 2040-3372
Editor: Royal Society of Chemistry
DOI: 10.1039/d1nr08206j

Positional Fluorination of Fmoc-Phenylalanine Modulates Hydrogel Structure and Antibacterial Activity

Autores: Ofir Doitch, Noam Rattner, Dana Cohen-Gerassi, Yoav Dan, Sigal Rencus-Lazar, Moran Aviv, Lihi Adler-Abramovich
Publicado en: Biomacromolecules, 2025, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.5c00481

Disordered Protein Stabilization by Co-Assembly of Short Peptides Enables Formation of Robust Membranes

Autores: Moumita Ghosh; Anna Majkowska; Rajkumar Mirsa; Santu Bera; José Carlos Rodríguez-Cabello; Alvaro Mata; Lihi Adler-Abramovich
Publicado en: ACS Applied Materials Interfaces, Edición 14, 2022, Página(s) 464–473, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.1c22136

Modulating hierarchical self-assembly in thermoresponsive intrinsically disordered proteins through high-temperature incubation time

Autores: Vaishali Sethi, Dana Cohen-Gerassi, Sagi Meir, Max Ney, Yulia Shmidov, Gil Koren, Lihi Adler-Abramovich, Ashutosh Chilkoti & Roy Beck
Publicado en: Scientific Reports, Edición 13, 2023, Página(s) 21688, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-48483-w

Exploiting Minimalistic Backbone Engineered ?-Phenylalanine for the Formation of Supramolecular Co-Polymer

Autores: Rajkumar Misra; Yiming Tang; Yujie Chen; Priyadarshi Chakraborty; Francesca Netti; Thangavel Vijayakanth; Linda J. W. Shimon; Guanghong Wei; Lihi Adler-Abramovich
Publicado en: Macromolecular Rapid Communications, Edición 1, 2022, Página(s) 2200223, ISSN 1521-3927
Editor: Wiley-VCH GmbH
DOI: 10.1002/marc.202200223

An atomistic view of rigid crystalline supramolecular polymers derived from short amphiphilic, α,β hybrid peptide

Autores: Rajkumar Misra; Francesca Netti; Gil Koren; Yoav Dan; Priyadarshi Chakraborty; Sidney R. Cohen; Linda J. W. Shimon; Roy Beck; Lihi Adler-Abramovich
Publicado en: Polymer Chemistry, Edición 13, 2022, Página(s) 6223-6228, ISSN 1759-9962
Editor: Royal Society of Chemistry
DOI: 10.1039/d2py01072k

Atomic Insight into Short Helical Peptide Comprised of Consecutive Multiple Aromatic Residues

Autores: Rajkumar Misra; Thangavel Vijayakanth; Linda J W Shimon; Lihi Adler-Abramovich
Publicado en: Chemical Communications, Edición 58, 2022, Página(s) 6445-6448, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc01038k

Hyaluronic Acid and a Short Peptide Improve the Performance of a PCL Electrospun Fibrous Scaffold Designed for Bone Tissue Engineering Applications

Autores: Dana Rachmiel; Inbar Anconina; Safra Rudnick-Glick; Michal Halperin-Sternfeld; Lihi Adler-Abramovich; Amit Sitt
Publicado en: International Journal of Molecular Sciences, Edición 22, 2021, Página(s) 242, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22052425

The Effects of a Short Self-Assembling Peptide on the Physical and Biological Properties of Biopolymer Hydrogels

Autores: Chowdhuri, S., Ghosh, M., Adler-Abramovich, L.*, Das, D
Publicado en: Pharmaceutics, Edición 13, 2021, Página(s) 1602, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101602

In Vitro Evaluation of a Semi‐Autologous Fibrin Sealant for Surgical Applications

Autores: Uri Elbaz, Ori Berliner, Shavit Tabo, Shani Yeshayahu, Reut Kesner, Dana Cohen‐Gerassi, Lihi Adler‐Abramovich, Michal Halperin‐Sternfeld, Moran Aviv
Publicado en: Macromolecular Bioscience, Edición 25, 2025, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202400165

Red Microalgae Sulfated Polysaccharide-Peptide Composite Hydrogels as Scaffolds for Tissue Engineering

Autores: Michal Halperin-Sternfeld; Gal Netanel Liberman; Raha Kannan; Francesca Netti; Peter X Ma; Shoshana Malis Arad; Lihi Adler-Abramovich
Publicado en: Biomedicines, Edición 10, 2022, Página(s) 1388, ISSN 2227-9059
Editor: MDPI
DOI: 10.3390/biomedicines10061388

Unveiling the Assembly Transition of Diphenylalanine and Its Analogs: from Oligomer Equilibrium to Nanocluster Formation

Autores: Chang Liu, Yoav Dan, Ji Yun, Lihi Adler-Abramovich, Jinghui Luo
Publicado en: ACS Nano, Edición 19, 2025, Página(s) 13250-13263, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.5c00433