Comprehending Prokaryotic Argonaute Systems

Project Information

COMPASS

Grant agreement ID: 948783

DOI

10.3030/948783

EC signature date 4 November 2020

Start date 1 December 2020

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 496 463,00

EU contribution

€ 1 496 463,00

Coordinated by

WAGENINGEN UNIVERSITY
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

RNA-guided RNA silencing by an Asgard archaeal Argonaute

Author(s): Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A. Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J. G. Ettema, Martin Jinek, Ian J. MacRae, Chirlmin Joo, Daan C. Swarts, Fabai Wu
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49452-1

Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA

Author(s): Pilar Bobadilla Ugarte, Stefanie Halter, Sumanth K. Mutte, Clint Heijstek, Theophile Niault, Ilya Terenin, Patrick Barendse, Balwina Koopal, Mark Roosjen, Sjef Boeren, Vasili Hauryliuk, Martin Jinek, Adrie H. Westphal, Daan C. Swarts
Published in: Molecular Cell, Issue 85, 2025, Page(s) 1920-1937.e10, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2025.03.025

Short prokaryotic Argonaute systems trigger cell death upon detection of invading DNA

Author(s): Balwina Koopal, Ana Potocnik, Sumanth K. Mutte, Cristian Aparicio-Maldonado, Simon Lindhoud, Jacques J.M. Vervoort, Stan J.J. Brouns, Daan C.Swarts
Published in: Cell, Issue Volume 185, Issue 9, 2022, Page(s) 1471-1486, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.03.012

A long look at short prokaryotic Argonautes

Author(s): Balwina Koopal; Sumanth K. Mutte; Daan C. Swarts
Published in: Trends in Cell Biology, Issue Volume 33, Issue 7, 2023, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2022.10.005

Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA

Author(s): Giada Finocchio, Balwina Koopal, Ana Potocnik, Clint Heijstek, Adrie H Westphal, Martin Jinek, Daan C Swarts
Published in: Nucleic Acids Research, Issue 52, 2024, Page(s) 2012-2029, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad1248

Argonaute proteins confer immunity in all domains of life

Author(s): Bobadilla Ugarte, Pilar; Barendse, Patrick; Swarts, Daan C.
Published in: Current Opinion in Microbiology, Issue Volume 74, 2023, ISSN 1369-5274
Publisher: Elsevier BV
DOI: 10.1016/j.mib.2023.102313

Non-peer reviewed articles (1)

Short prokaryotic Argonaute system repurposed as a nucleic acid detection tool.

Author(s): Ana Potocnik; Daan C. Swarts
Published in: Clinical and Translational Medicine, 2022, ISSN 2001-1326
Publisher: Wiley online library
DOI: 10.1002/ctm2.1059