Novel contrast agents that stay visible longer enhance medical imaging
The ability to non-invasively visualise the human body has played a critical role in enhancing the diagnosis, treatment and outcomes of numerous diseases. Nuclear magnetic resonance (NMR) imaging is one of those powerful imaging techniques that helps clinicians see cells and tissues and observe physiological processes. Signal enhancement methods have been developed to overcome sensitivity challenges of NMR and molecules with highly enhanced signals have in recent years been introduced as contrast agents for biomedical imaging. However, these agents are only active for a couple of minutes. The EU-funded HyperULFNMR project is designing functional contrast molecules for a class of NMR devices that will have significantly longer lifetimes and simultaneously reveal molecular coupling patterns, spurring advances in both research and diagnostics.
Fields of science
Funding SchemeERC-STG - Starting Grant