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Biocatalytic alkylation: fitting enzymes for selective C-C bond formations

Project description

Selective and sustainable C-alkylation harnesses synthetic enzymes

Carbon is the main building block of organic compounds. Carbon-carbon bonds are fundamental linkages and among the least amenable to manipulation by synthetic chemists, their breaking and making often requiring catalysts. Alkylation of carbon (C-alkylation), the addition or substitution of an alkyl group consisting of carbon atoms bonded only to hydrogens, is one of the most important reactions. Application areas include organic chemistry, manufacturing of fuels and medicine. The EU-funded BioAlk project will build on work utilising enzymes, nature's catalysts, to facilitate the reaction. The goal is to significantly enhance selectivity to minimise undesirable products and maximise selective production of valuable and desired compounds.

Call for proposal

ERC-2020-STG
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Host institution

TECHNISCHE UNIVERSITEIT DELFT
Address
Stevinweg 1
2628 CN Delft
Netherlands

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Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 625 000

Beneficiaries (1)

TECHNISCHE UNIVERSITEIT DELFT
Netherlands
EU contribution
€ 1 625 000
Address
Stevinweg 1
2628 CN Delft

See on map

Activity type
Higher or Secondary Education Establishments