Development of ultra-resolution imaging for brain synapse studies
Modern imaging technologies are unable to present the topology of proteins accurately as the best super-resolution tools’ limits are at 20–30 nm, which is several times more than the sizes of the individual proteins. The EU-funded ULTRARESOLUTION project aims to develop reliable ultra-resolution imaging with a true molecular resolution of 1–5 nm. The project will combine optics-based super-resolution technologies with the innovative physical expansion of the samples. This approach will be employed to decipher the functional organisation of key components in brain synapses. The final goal is to establish simple protocols to expand the application of ultra resolution to every biomedical laboratory.
Fields of science
Call for proposal
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Funding SchemeERC-SyG - Synergy grant