RESTORING CARDIAC MECHANICAL FUNCTION BY POLYMERIC ARTIFICIAL MUSCULAR TISSUE

Project Information

REPAIR

Grant agreement ID: 952166

DOI 10.3030/952166

EC signature date 22 June 2020

Start date 1 September 2020

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 3 909 707,50

EU contribution € 3 909 707,50

Coordinated by

UNIVERSITA DEGLI STUDI DI FIRENZE
Italy

Deliverables

Websites, patent fillings, videos etc. (3)

Project Website
Preliminar Promotional material

Promotional material including updated results

Dissemination Kit for conferences and events

Dissemination Kit for conferences and events brochure summary explanantory videos

Open Research Data Pilot (2)

Data management plan.

Data management plan

Update of the data management plan

The data management plan will be updated

Publications

Peer reviewed articles (9)

Optical clearing in cardiac imaging: A comparative study

Author(s): Olianti C, Giardini F, Lazzeri E, Costantini I, Silvestri L, Coppini R, Cerbai E, Pavone FS, Sacconi L.
Published in: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2022, ISSN 0079-6107
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.pbiomolbio.2021.07.012

Quantification of Myocyte Disarray in Human Cardiac Tissue

Author(s): Giardini F, Lazzeri E, Vitale G, Ferrantini C, Costantini I, Pavone FS, Poggesi C, Bocchi L, Sacconi L.
Published in: Frontiers in Physiology, 2021, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.750364

Photoresponsive Polymer-Based Biomimetic ContractileUnits as Building Block for Artificial Muscles

Author(s): Giulia Vitale, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Chiara Tesi, Corrado Poggesi, Elisabetta Cerbai, Diederik S. Wiersma, Camilla Parmeggiani,* Cecilia Ferrantini,* and Leonardo Sacconi
Published in: Macromolecular Materials and Engineering, 2022, ISSN 1439-2054
Publisher: Wiley
DOI: 10.1002/mame.202200187

Mesoscopic Optical Imaging of Whole Mouse Heart

Author(s): Giardini F, Lazzeri E, Olianti C, Beconi G, Costantini I, Silvestri L, Cerbai E, Pavone FS, Sacconi L.
Published in: Journal of Visualized Experiments, 2021, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/62795

The Role of Crosslinker Molecular Structure on Mechanicaland Light-Actuation Properties in Liquid Crystalline Networks.

Author(s): Simone Donato, Daniele Martella, Martina Salzano de Luna, Giulia Arecchi, Silvia Querceto, Cecilia Ferrantini, Leonardo Sacconi, Pierre-Louis Brient, Camille Chatard, Alain Graillot, Diederik S. Wiersma, Camilla Parmeggiani
Published in: Macromol. Rapid Commun., 2023, ISSN 1022-1336
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/marc.202200958

Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1

Author(s): D’Alessandro, Elisa, Billy Scaf, Chantal Munts, Arne van Hunnik, Christopher J. Trevelyan, Sander Verheule, Henri M. H. Spronk, Neil A. Turner, Hugo ten Cate, Ulrich Schotten, and et al.
Published in: Cells, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10112958

Cell instructive Liquid Crystalline Networks for myotube formation

Author(s): Daniele Martella, Michele Mannelli, Roberta Squecco, Rachele Garella, Eglantina Idrizaj, Diego Antonioli, Michele Laus, Diederik S. Wiersma, Tania Gamberi, Paolo Paoli, Camilla Parmeggiani, Tania Fiaschi
Published in: iScience, 2021, ISSN 2589-0042
Publisher: CellPress
DOI: 10.1016/j.isci.2021.103077

Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM

Author(s): Josè Manuel Pioner, Giulia Vitale, Sonette Steczina, Marianna Langione, Francesca Margara, Lorenzo Santini, Francesco Giardini, Erica Lazzeri, Nicoletta Piroddi, Beatrice Scellini, Chiara Palandri, Maike Schuldt, Valentina Spinelli, Francesca Girolami, Francesco Mazzarotto, Jolanda van der Velden, Elisabetta Cerbai, Chiara Tesi, Iacopo Olivotto, Alfonso Bueno-Orovio, Leonardo Sacconi, Raffaele Co
Published in: Circulation Research, 2023, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.122.321956

Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations

Author(s): Josè Manuel Pioner, Giulia Vitale, Francesca Gentile, Beatrice Scellini, Nicoletta Piroddi, Elisabetta Cerbai, Iacopo Olivotto, Jil Tardiff, Raffaele Coppini, Chiara Tesi, Corrado Poggesi and Cecilia Ferrantini*
Published in: frontiers in physiology, 2022, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.864547